4ZN0

Structure of the NADPH-dependent thioredoxin reductase from Methanosarcina mazei

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0016491	molecular_function	oxidoreductase activity
A	0019430	biological_process	removal of superoxide radicals
A	0045454	biological_process	cell redox homeostasis
B	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0016491	molecular_function	oxidoreductase activity
B	0019430	biological_process	removal of superoxide radicals
B	0045454	biological_process	cell redox homeostasis
C	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0016491	molecular_function	oxidoreductase activity
C	0019430	biological_process	removal of superoxide radicals
C	0045454	biological_process	cell redox homeostasis
D	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0016491	molecular_function	oxidoreductase activity
D	0019430	biological_process	removal of superoxide radicals
D	0045454	biological_process	cell redox homeostasis

Functional Information from PROSITE/UniProt

site_id	PS00573
Number of Residues	21
Details	PYRIDINE_REDOX_2 Pyridine nucleotide-disulphide oxidoreductases class-II active site. CaiCDGpf..FrnkiVaVVGGGN

Chain	Residue	Details
A	CYS133-ASN153

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