4ZMR
Structural characterization of the full-length response regulator spr1814 in complex with a phosphate analogue reveals a novel conformational plasticity of the linker region
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000156 | molecular_function | phosphorelay response regulator activity |
| A | 0000160 | biological_process | phosphorelay signal transduction system |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0032993 | cellular_component | protein-DNA complex |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000156 | molecular_function | phosphorelay response regulator activity |
| B | 0000160 | biological_process | phosphorelay signal transduction system |
| B | 0000976 | molecular_function | transcription cis-regulatory region binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0032993 | cellular_component | protein-DNA complex |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 201 |
| Chain | Residue |
| A | ASP8 |
| A | ASP53 |
| A | GLU55 |
| A | BEF202 |
| A | HOH322 |
| A | HOH393 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue BEF A 202 |
| Chain | Residue |
| A | THR81 |
| A | THR82 |
| A | PHE83 |
| A | LYS103 |
| A | MG201 |
| A | HOH322 |
| A | HOH393 |
| A | HOH409 |
| A | ASP53 |
| A | VAL54 |
| A | GLU55 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 201 |
| Chain | Residue |
| B | ASP8 |
| B | ASP53 |
| B | GLU55 |
| B | BEF202 |
| B | HOH325 |
| B | HOH389 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue BEF B 202 |
| Chain | Residue |
| B | ASP53 |
| B | VAL54 |
| B | GLU55 |
| B | THR81 |
| B | THR82 |
| B | PHE83 |
| B | LYS103 |
| B | MG201 |
| B | HOH325 |
| B | HOH389 |
| B | HOH413 |
Functional Information from PROSITE/UniProt
| site_id | PS00622 |
| Number of Residues | 28 |
| Details | HTH_LUXR_1 LuxR-type HTH domain signature. GlsNqeIAdqLyLsngTIrnYvtNIlsK |
| Chain | Residue | Details |
| A | GLY153-LYS180 |
