4ZHH

Siderocalin-mediated recognition and cellular uptake of actinides

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002020	molecular_function	protease binding
A	0002376	biological_process	immune system process
A	0005506	molecular_function	iron ion binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0006811	biological_process	monoatomic ion transport
A	0006826	biological_process	iron ion transport
A	0006915	biological_process	apoptotic process
A	0006953	biological_process	acute-phase response
A	0006979	biological_process	response to oxidative stress
A	0007614	biological_process	short-term memory
A	0007616	biological_process	long-term memory
A	0009410	biological_process	response to xenobiotic stimulus
A	0009615	biological_process	response to virus
A	0009617	biological_process	response to bacterium
A	0009635	biological_process	response to herbicide
A	0009636	biological_process	response to toxic substance
A	0009637	biological_process	response to blue light
A	0009750	biological_process	response to fructose
A	0010040	biological_process	response to iron(II) ion
A	0010046	biological_process	response to mycotoxin
A	0010595	biological_process	positive regulation of endothelial cell migration
A	0010628	biological_process	positive regulation of gene expression
A	0015891	biological_process	siderophore transport
A	0031346	biological_process	positive regulation of cell projection organization
A	0031410	cellular_component	cytoplasmic vesicle
A	0031667	biological_process	response to nutrient levels
A	0031669	biological_process	cellular response to nutrient levels
A	0032496	biological_process	response to lipopolysaccharide
A	0035580	cellular_component	specific granule lumen
A	0036094	molecular_function	small molecule binding
A	0036295	biological_process	cellular response to increased oxygen levels
A	0042742	biological_process	defense response to bacterium
A	0042802	molecular_function	identical protein binding
A	0043065	biological_process	positive regulation of apoptotic process
A	0043525	biological_process	positive regulation of neuron apoptotic process
A	0045087	biological_process	innate immune response
A	0060205	cellular_component	cytoplasmic vesicle lumen
A	0070062	cellular_component	extracellular exosome
A	0070301	biological_process	cellular response to hydrogen peroxide
A	0071222	biological_process	cellular response to lipopolysaccharide
A	0071347	biological_process	cellular response to interleukin-1
A	0071354	biological_process	cellular response to interleukin-6
A	0071356	biological_process	cellular response to tumor necrosis factor
A	0071456	biological_process	cellular response to hypoxia
A	0071481	biological_process	cellular response to X-ray
A	0097192	biological_process	extrinsic apoptotic signaling pathway in absence of ligand
A	0110090	biological_process	positive regulation of hippocampal neuron apoptotic process
A	0110091	biological_process	negative regulation of hippocampal neuron apoptotic process
A	0120162	biological_process	positive regulation of cold-induced thermogenesis
A	0140315	molecular_function	iron ion sequestering activity
A	1903428	biological_process	positive regulation of reactive oxygen species biosynthetic process
A	1903981	molecular_function	enterobactin binding
A	1904373	biological_process	response to kainic acid
A	1904440	biological_process	positive regulation of iron ion import across plasma membrane
A	1904646	biological_process	cellular response to amyloid-beta
A	1905956	biological_process	positive regulation of endothelial tube morphogenesis
A	1990090	biological_process	cellular response to nerve growth factor stimulus
A	2000379	biological_process	positive regulation of reactive oxygen species metabolic process
B	0002020	molecular_function	protease binding
B	0002376	biological_process	immune system process
B	0005506	molecular_function	iron ion binding
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0006811	biological_process	monoatomic ion transport
B	0006826	biological_process	iron ion transport
B	0006915	biological_process	apoptotic process
B	0006953	biological_process	acute-phase response
B	0006979	biological_process	response to oxidative stress
B	0007614	biological_process	short-term memory
B	0007616	biological_process	long-term memory
B	0009410	biological_process	response to xenobiotic stimulus
B	0009615	biological_process	response to virus
B	0009617	biological_process	response to bacterium
B	0009635	biological_process	response to herbicide
B	0009636	biological_process	response to toxic substance
B	0009637	biological_process	response to blue light
B	0009750	biological_process	response to fructose
B	0010040	biological_process	response to iron(II) ion
B	0010046	biological_process	response to mycotoxin
B	0010595	biological_process	positive regulation of endothelial cell migration
B	0010628	biological_process	positive regulation of gene expression
B	0015891	biological_process	siderophore transport
B	0031346	biological_process	positive regulation of cell projection organization
B	0031410	cellular_component	cytoplasmic vesicle
B	0031667	biological_process	response to nutrient levels
B	0031669	biological_process	cellular response to nutrient levels
B	0032496	biological_process	response to lipopolysaccharide
B	0035580	cellular_component	specific granule lumen
B	0036094	molecular_function	small molecule binding
B	0036295	biological_process	cellular response to increased oxygen levels
B	0042742	biological_process	defense response to bacterium
B	0042802	molecular_function	identical protein binding
B	0043065	biological_process	positive regulation of apoptotic process
B	0043525	biological_process	positive regulation of neuron apoptotic process
B	0045087	biological_process	innate immune response
B	0060205	cellular_component	cytoplasmic vesicle lumen
B	0070062	cellular_component	extracellular exosome
B	0070301	biological_process	cellular response to hydrogen peroxide
B	0071222	biological_process	cellular response to lipopolysaccharide
B	0071347	biological_process	cellular response to interleukin-1
B	0071354	biological_process	cellular response to interleukin-6
B	0071356	biological_process	cellular response to tumor necrosis factor
B	0071456	biological_process	cellular response to hypoxia
B	0071481	biological_process	cellular response to X-ray
B	0097192	biological_process	extrinsic apoptotic signaling pathway in absence of ligand
B	0110090	biological_process	positive regulation of hippocampal neuron apoptotic process
B	0110091	biological_process	negative regulation of hippocampal neuron apoptotic process
B	0120162	biological_process	positive regulation of cold-induced thermogenesis
B	0140315	molecular_function	iron ion sequestering activity
B	1903428	biological_process	positive regulation of reactive oxygen species biosynthetic process
B	1903981	molecular_function	enterobactin binding
B	1904373	biological_process	response to kainic acid
B	1904440	biological_process	positive regulation of iron ion import across plasma membrane
B	1904646	biological_process	cellular response to amyloid-beta
B	1905956	biological_process	positive regulation of endothelial tube morphogenesis
B	1990090	biological_process	cellular response to nerve growth factor stimulus
B	2000379	biological_process	positive regulation of reactive oxygen species metabolic process
C	0002020	molecular_function	protease binding
C	0002376	biological_process	immune system process
C	0005506	molecular_function	iron ion binding
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0006811	biological_process	monoatomic ion transport
C	0006826	biological_process	iron ion transport
C	0006915	biological_process	apoptotic process
C	0006953	biological_process	acute-phase response
C	0006979	biological_process	response to oxidative stress
C	0007614	biological_process	short-term memory
C	0007616	biological_process	long-term memory
C	0009410	biological_process	response to xenobiotic stimulus
C	0009615	biological_process	response to virus
C	0009617	biological_process	response to bacterium
C	0009635	biological_process	response to herbicide
C	0009636	biological_process	response to toxic substance
C	0009637	biological_process	response to blue light
C	0009750	biological_process	response to fructose
C	0010040	biological_process	response to iron(II) ion
C	0010046	biological_process	response to mycotoxin
C	0010595	biological_process	positive regulation of endothelial cell migration
C	0010628	biological_process	positive regulation of gene expression
C	0015891	biological_process	siderophore transport
C	0031346	biological_process	positive regulation of cell projection organization
C	0031410	cellular_component	cytoplasmic vesicle
C	0031667	biological_process	response to nutrient levels
C	0031669	biological_process	cellular response to nutrient levels
C	0032496	biological_process	response to lipopolysaccharide
C	0035580	cellular_component	specific granule lumen
C	0036094	molecular_function	small molecule binding
C	0036295	biological_process	cellular response to increased oxygen levels
C	0042742	biological_process	defense response to bacterium
C	0042802	molecular_function	identical protein binding
C	0043065	biological_process	positive regulation of apoptotic process
C	0043525	biological_process	positive regulation of neuron apoptotic process
C	0045087	biological_process	innate immune response
C	0060205	cellular_component	cytoplasmic vesicle lumen
C	0070062	cellular_component	extracellular exosome
C	0070301	biological_process	cellular response to hydrogen peroxide
C	0071222	biological_process	cellular response to lipopolysaccharide
C	0071347	biological_process	cellular response to interleukin-1
C	0071354	biological_process	cellular response to interleukin-6
C	0071356	biological_process	cellular response to tumor necrosis factor
C	0071456	biological_process	cellular response to hypoxia
C	0071481	biological_process	cellular response to X-ray
C	0097192	biological_process	extrinsic apoptotic signaling pathway in absence of ligand
C	0110090	biological_process	positive regulation of hippocampal neuron apoptotic process
C	0110091	biological_process	negative regulation of hippocampal neuron apoptotic process
C	0120162	biological_process	positive regulation of cold-induced thermogenesis
C	0140315	molecular_function	iron ion sequestering activity
C	1903428	biological_process	positive regulation of reactive oxygen species biosynthetic process
C	1903981	molecular_function	enterobactin binding
C	1904373	biological_process	response to kainic acid
C	1904440	biological_process	positive regulation of iron ion import across plasma membrane
C	1904646	biological_process	cellular response to amyloid-beta
C	1905956	biological_process	positive regulation of endothelial tube morphogenesis
C	1990090	biological_process	cellular response to nerve growth factor stimulus
C	2000379	biological_process	positive regulation of reactive oxygen species metabolic process
D	0002020	molecular_function	protease binding
D	0002376	biological_process	immune system process
D	0005506	molecular_function	iron ion binding
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0006811	biological_process	monoatomic ion transport
D	0006826	biological_process	iron ion transport
D	0006915	biological_process	apoptotic process
D	0006953	biological_process	acute-phase response
D	0006979	biological_process	response to oxidative stress
D	0007614	biological_process	short-term memory
D	0007616	biological_process	long-term memory
D	0009410	biological_process	response to xenobiotic stimulus
D	0009615	biological_process	response to virus
D	0009617	biological_process	response to bacterium
D	0009635	biological_process	response to herbicide
D	0009636	biological_process	response to toxic substance
D	0009637	biological_process	response to blue light
D	0009750	biological_process	response to fructose
D	0010040	biological_process	response to iron(II) ion
D	0010046	biological_process	response to mycotoxin
D	0010595	biological_process	positive regulation of endothelial cell migration
D	0010628	biological_process	positive regulation of gene expression
D	0015891	biological_process	siderophore transport
D	0031346	biological_process	positive regulation of cell projection organization
D	0031410	cellular_component	cytoplasmic vesicle
D	0031667	biological_process	response to nutrient levels
D	0031669	biological_process	cellular response to nutrient levels
D	0032496	biological_process	response to lipopolysaccharide
D	0035580	cellular_component	specific granule lumen
D	0036094	molecular_function	small molecule binding
D	0036295	biological_process	cellular response to increased oxygen levels
D	0042742	biological_process	defense response to bacterium
D	0042802	molecular_function	identical protein binding
D	0043065	biological_process	positive regulation of apoptotic process
D	0043525	biological_process	positive regulation of neuron apoptotic process
D	0045087	biological_process	innate immune response
D	0060205	cellular_component	cytoplasmic vesicle lumen
D	0070062	cellular_component	extracellular exosome
D	0070301	biological_process	cellular response to hydrogen peroxide
D	0071222	biological_process	cellular response to lipopolysaccharide
D	0071347	biological_process	cellular response to interleukin-1
D	0071354	biological_process	cellular response to interleukin-6
D	0071356	biological_process	cellular response to tumor necrosis factor
D	0071456	biological_process	cellular response to hypoxia
D	0071481	biological_process	cellular response to X-ray
D	0097192	biological_process	extrinsic apoptotic signaling pathway in absence of ligand
D	0110090	biological_process	positive regulation of hippocampal neuron apoptotic process
D	0110091	biological_process	negative regulation of hippocampal neuron apoptotic process
D	0120162	biological_process	positive regulation of cold-induced thermogenesis
D	0140315	molecular_function	iron ion sequestering activity
D	1903428	biological_process	positive regulation of reactive oxygen species biosynthetic process
D	1903981	molecular_function	enterobactin binding
D	1904373	biological_process	response to kainic acid
D	1904440	biological_process	positive regulation of iron ion import across plasma membrane
D	1904646	biological_process	cellular response to amyloid-beta
D	1905956	biological_process	positive regulation of endothelial tube morphogenesis
D	1990090	biological_process	cellular response to nerve growth factor stimulus
D	2000379	biological_process	positive regulation of reactive oxygen species metabolic process
E	0002020	molecular_function	protease binding
E	0002376	biological_process	immune system process
E	0005506	molecular_function	iron ion binding
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0006811	biological_process	monoatomic ion transport
E	0006826	biological_process	iron ion transport
E	0006915	biological_process	apoptotic process
E	0006953	biological_process	acute-phase response
E	0006979	biological_process	response to oxidative stress
E	0007614	biological_process	short-term memory
E	0007616	biological_process	long-term memory
E	0009410	biological_process	response to xenobiotic stimulus
E	0009615	biological_process	response to virus
E	0009617	biological_process	response to bacterium
E	0009635	biological_process	response to herbicide
E	0009636	biological_process	response to toxic substance
E	0009637	biological_process	response to blue light
E	0009750	biological_process	response to fructose
E	0010040	biological_process	response to iron(II) ion
E	0010046	biological_process	response to mycotoxin
E	0010595	biological_process	positive regulation of endothelial cell migration
E	0010628	biological_process	positive regulation of gene expression
E	0015891	biological_process	siderophore transport
E	0031346	biological_process	positive regulation of cell projection organization
E	0031410	cellular_component	cytoplasmic vesicle
E	0031667	biological_process	response to nutrient levels
E	0031669	biological_process	cellular response to nutrient levels
E	0032496	biological_process	response to lipopolysaccharide
E	0035580	cellular_component	specific granule lumen
E	0036094	molecular_function	small molecule binding
E	0036295	biological_process	cellular response to increased oxygen levels
E	0042742	biological_process	defense response to bacterium
E	0042802	molecular_function	identical protein binding
E	0043065	biological_process	positive regulation of apoptotic process
E	0043525	biological_process	positive regulation of neuron apoptotic process
E	0045087	biological_process	innate immune response
E	0060205	cellular_component	cytoplasmic vesicle lumen
E	0070062	cellular_component	extracellular exosome
E	0070301	biological_process	cellular response to hydrogen peroxide
E	0071222	biological_process	cellular response to lipopolysaccharide
E	0071347	biological_process	cellular response to interleukin-1
E	0071354	biological_process	cellular response to interleukin-6
E	0071356	biological_process	cellular response to tumor necrosis factor
E	0071456	biological_process	cellular response to hypoxia
E	0071481	biological_process	cellular response to X-ray
E	0097192	biological_process	extrinsic apoptotic signaling pathway in absence of ligand
E	0110090	biological_process	positive regulation of hippocampal neuron apoptotic process
E	0110091	biological_process	negative regulation of hippocampal neuron apoptotic process
E	0120162	biological_process	positive regulation of cold-induced thermogenesis
E	0140315	molecular_function	iron ion sequestering activity
E	1903428	biological_process	positive regulation of reactive oxygen species biosynthetic process
E	1903981	molecular_function	enterobactin binding
E	1904373	biological_process	response to kainic acid
E	1904440	biological_process	positive regulation of iron ion import across plasma membrane
E	1904646	biological_process	cellular response to amyloid-beta
E	1905956	biological_process	positive regulation of endothelial tube morphogenesis
E	1990090	biological_process	cellular response to nerve growth factor stimulus
E	2000379	biological_process	positive regulation of reactive oxygen species metabolic process
F	0002020	molecular_function	protease binding
F	0002376	biological_process	immune system process
F	0005506	molecular_function	iron ion binding
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0006811	biological_process	monoatomic ion transport
F	0006826	biological_process	iron ion transport
F	0006915	biological_process	apoptotic process
F	0006953	biological_process	acute-phase response
F	0006979	biological_process	response to oxidative stress
F	0007614	biological_process	short-term memory
F	0007616	biological_process	long-term memory
F	0009410	biological_process	response to xenobiotic stimulus
F	0009615	biological_process	response to virus
F	0009617	biological_process	response to bacterium
F	0009635	biological_process	response to herbicide
F	0009636	biological_process	response to toxic substance
F	0009637	biological_process	response to blue light
F	0009750	biological_process	response to fructose
F	0010040	biological_process	response to iron(II) ion
F	0010046	biological_process	response to mycotoxin
F	0010595	biological_process	positive regulation of endothelial cell migration
F	0010628	biological_process	positive regulation of gene expression
F	0015891	biological_process	siderophore transport
F	0031346	biological_process	positive regulation of cell projection organization
F	0031410	cellular_component	cytoplasmic vesicle
F	0031667	biological_process	response to nutrient levels
F	0031669	biological_process	cellular response to nutrient levels
F	0032496	biological_process	response to lipopolysaccharide
F	0035580	cellular_component	specific granule lumen
F	0036094	molecular_function	small molecule binding
F	0036295	biological_process	cellular response to increased oxygen levels
F	0042742	biological_process	defense response to bacterium
F	0042802	molecular_function	identical protein binding
F	0043065	biological_process	positive regulation of apoptotic process
F	0043525	biological_process	positive regulation of neuron apoptotic process
F	0045087	biological_process	innate immune response
F	0060205	cellular_component	cytoplasmic vesicle lumen
F	0070062	cellular_component	extracellular exosome
F	0070301	biological_process	cellular response to hydrogen peroxide
F	0071222	biological_process	cellular response to lipopolysaccharide
F	0071347	biological_process	cellular response to interleukin-1
F	0071354	biological_process	cellular response to interleukin-6
F	0071356	biological_process	cellular response to tumor necrosis factor
F	0071456	biological_process	cellular response to hypoxia
F	0071481	biological_process	cellular response to X-ray
F	0097192	biological_process	extrinsic apoptotic signaling pathway in absence of ligand
F	0110090	biological_process	positive regulation of hippocampal neuron apoptotic process
F	0110091	biological_process	negative regulation of hippocampal neuron apoptotic process
F	0120162	biological_process	positive regulation of cold-induced thermogenesis
F	0140315	molecular_function	iron ion sequestering activity
F	1903428	biological_process	positive regulation of reactive oxygen species biosynthetic process
F	1903981	molecular_function	enterobactin binding
F	1904373	biological_process	response to kainic acid
F	1904440	biological_process	positive regulation of iron ion import across plasma membrane
F	1904646	biological_process	cellular response to amyloid-beta
F	1905956	biological_process	positive regulation of endothelial tube morphogenesis
F	1990090	biological_process	cellular response to nerve growth factor stimulus
F	2000379	biological_process	positive regulation of reactive oxygen species metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	binding site for residue SM A 201

Chain	Residue
A	4OL202

---

site_id	AC2
Number of Residues	17
Details	binding site for residue 4OL A 202

Chain	Residue
A	PHE123
A	LYS125
A	LYS134
A	SM201
A	HOH307
A	HOH322
A	HOH339
A	HOH344
A	HOH372
A	ALA40
A	ILE41
A	TYR52
A	SER68
A	TRP79
A	ARG81
A	TYR100
A	TYR106

---

site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 A 203

Chain	Residue
A	ILE8
A	ASN164
A	HIS165
A	HOH304
B	LYS75

---

site_id	AC4
Number of Residues	4
Details	binding site for residue GOL A 204

Chain	Residue
A	GLN117
A	HIS118
A	HOH302
E	ASN116

---

site_id	AC5
Number of Residues	5
Details	binding site for residue CL A 205

Chain	Residue
A	THR54
A	ARG81
A	TYR138
A	HOH348
A	HOH388

---

site_id	AC6
Number of Residues	1
Details	binding site for residue SM B 201

Chain	Residue
B	4OL202

---

site_id	AC7
Number of Residues	16
Details	binding site for residue 4OL B 202

Chain	Residue
B	ALA40
B	ILE41
B	TYR52
B	SER68
B	LEU70
B	TRP79
B	TYR100
B	TYR106
B	LYS125
B	LYS134
B	SM201
B	HOH302
B	HOH319
B	HOH323
B	HOH325
B	HOH340

---

site_id	AC8
Number of Residues	2
Details	binding site for residue SO4 B 203

Chain	Residue
B	ASN114
D	GLN117

---

site_id	AC9
Number of Residues	4
Details	binding site for residue CL B 204

Chain	Residue
B	THR54
B	TYR138
B	HOH356
B	HOH374

---

site_id	AD1
Number of Residues	1
Details	binding site for residue SM C 201

Chain	Residue
C	4OL202

---

site_id	AD2
Number of Residues	18
Details	binding site for residue 4OL C 202

Chain	Residue
C	ALA40
C	ILE41
C	TYR52
C	SER68
C	TRP79
C	ARG81
C	TYR100
C	TYR106
C	LYS125
C	LYS134
C	SM201
C	HOH301
C	HOH311
C	HOH314
C	HOH326
C	HOH340
C	HOH342
D	HOH305

---

site_id	AD3
Number of Residues	5
Details	binding site for residue SO4 C 203

Chain	Residue
A	GLN117
C	ASN114
C	HOH303
C	HOH306
C	HOH322

---

site_id	AD4
Number of Residues	4
Details	binding site for residue CL C 204

Chain	Residue
C	THR54
C	ARG81
C	TYR138
C	HOH359

---

site_id	AD5
Number of Residues	2
Details	binding site for residue CL C 205

Chain	Residue
C	SER112
C	HIS118

---

site_id	AD6
Number of Residues	1
Details	binding site for residue SM D 201

Chain	Residue
D	4OL202

---

site_id	AD7
Number of Residues	14
Details	binding site for residue 4OL D 202

Chain	Residue
D	HOH338
D	ALA40
D	ILE41
D	TYR52
D	SER68
D	TRP79
D	ARG81
D	TYR106
D	LYS125
D	LYS134
D	SM201
D	HOH304
D	HOH307
D	HOH319

---

site_id	AD8
Number of Residues	3
Details	binding site for residue GOL D 203

Chain	Residue
D	ASN114
D	HIS118
F	ASN116

---

site_id	AD9
Number of Residues	4
Details	binding site for residue CL D 204

Chain	Residue
D	THR54
D	ARG81
D	TYR138
D	HOH333

---

site_id	AE1
Number of Residues	2
Details	binding site for residue GOL D 205

Chain	Residue
D	LYS59
D	GLU60

---

site_id	AE2
Number of Residues	4
Details	binding site for residue GOL D 206

Chain	Residue
C	LYS75
D	ASN164
D	HIS165
D	HOH315

---

site_id	AE3
Number of Residues	3
Details	binding site for residue CL D 207

Chain	Residue
D	SER112
D	HIS118
D	ALA119

---

site_id	AE4
Number of Residues	1
Details	binding site for residue SM E 201

Chain	Residue
E	4OL202

---

site_id	AE5
Number of Residues	15
Details	binding site for residue 4OL E 202

Chain	Residue
E	ALA40
E	ILE41
E	TYR52
E	SER68
E	LEU70
E	TRP79
E	TYR106
E	PHE123
E	LYS125
E	LYS134
E	SM201
E	HOH301
E	HOH310
E	HOH321
E	HOH334

---

site_id	AE6
Number of Residues	4
Details	binding site for residue SO4 E 203

Chain	Residue
D	ARG154
E	THR145
E	SER146
E	HOH335

---

site_id	AE7
Number of Residues	3
Details	binding site for residue CL E 204

Chain	Residue
E	THR54
E	ARG81
E	TYR138

---

site_id	AE8
Number of Residues	1
Details	binding site for residue GOL E 205

Chain	Residue
E	LYS73

---

site_id	AE9
Number of Residues	1
Details	binding site for residue SM F 201

Chain	Residue
F	4OL202

---

site_id	AF1
Number of Residues	17
Details	binding site for residue 4OL F 202

Chain	Residue
F	ALA40
F	ILE41
F	TYR52
F	SER68
F	LEU70
F	TRP79
F	ARG81
F	TYR106
F	LYS125
F	LYS134
F	SM201
F	HOH303
F	HOH313
F	HOH314
F	HOH316
F	HOH349
F	HOH356

---

site_id	AF2
Number of Residues	4
Details	binding site for residue SO4 F 203

Chain	Residue
E	LYS75
F	PRO162
F	ASN164
F	HIS165

---

site_id	AF3
Number of Residues	3
Details	binding site for residue CL F 204

Chain	Residue
F	THR54
F	ARG81
F	TYR138

---

Functional Information from PROSITE/UniProt

site_id	PS00213
Number of Residues	14
Details	LIPOCALIN Lipocalin signature. NFQdnQFQGKWYVV

Chain	Residue	Details
A	ASN21-VAL34

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PDB","id":"1X89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1X8U","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CMP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15642259","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1X89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1X8U","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"10684642","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15084671","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16740002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7683678","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DFV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QQS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---