Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0005576 | cellular_component | extracellular region |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 301 |
| Chain | Residue |
| A | ASP70 |
| A | ASN72 |
| A | GLN75 |
| A | GLU77 |
| A | GLU80 |
| A | HOH557 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue 4O4 A 302 |
| Chain | Residue |
| A | TYR99 |
| A | PHE174 |
| A | ASP189 |
| A | ALA190 |
| A | GLN192 |
| A | SER195 |
| A | VAL213 |
| A | TRP215 |
| A | GLY216 |
| A | GLY219 |
| A | GLY226 |
| A | TYR228 |
| A | HOH495 |
| A | LYS96 |
| A | GLU97 |
| A | THR98 |
Functional Information from PROSITE/UniProt
| site_id | PS00010 |
| Number of Residues | 12 |
| Details | ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CkDglgeYtCtC |
| Chain | Residue | Details |
| B | CYS-26-CYS-15 | |
| site_id | PS00011 |
| Number of Residues | 26 |
| Details | GLA_1 Vitamin K-dependent carboxylation domain. EcmEEtCsyeearEvfedsdktne.FW |
| Chain | Residue | Details |
| B | GLU-71-TRP-46 | |
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. CtCleGfeGKnC |
| Chain | Residue | Details |
| B | CYS-17-CYS-6 | |
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| A | LEU53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAcqGDSGGPHV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
| site_id | PS01186 |
| Number of Residues | 12 |
| Details | EGF_2 EGF-like domain signature 2. CtCleGFegkn....C |
| Chain | Residue | Details |
| B | CYS-17-CYS-6 | |
| B | CYS21-CYS36 | |
| site_id | PS01187 |
| Number of Residues | 25 |
| Details | EGF_CA Calcium-binding EGF-like domain signature. DgDQCetsp..........Cqnqgk..CkDglgeYtC |
| Chain | Residue | Details |
| B | ASP-41-CYS-17 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| B | GLU-55 | |
| B | GLU-48 | |
| A | ASP102 | |
| A | SER195 | |
| B | GLU-71 | |
| B | GLU-68 | |
| B | GLU-67 | |
| B | GLU-62 | |
| B | GLU-61 | |
| B | GLU-58 | |
| Chain | Residue | Details |
| B | ASP-24 | |
