4ZCU

Structure of calcium-bound regulatory domain of the human ATP-Mg/Pi carrier in the P2 form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
B	0005509	molecular_function	calcium ion binding
C	0005509	molecular_function	calcium ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CA A 1001

Chain	Residue
A	ASP32
A	ASN34
A	ASP36
A	VAL38
A	GLU43
A	HOH1119

---

site_id	AC2
Number of Residues	6
Details	binding site for residue CA A 1002

Chain	Residue
A	LYS74
A	GLU79
A	HOH1112
A	ASP68
A	ASN70
A	ASP72

---

site_id	AC3
Number of Residues	6
Details	binding site for residue CA A 1003

Chain	Residue
A	ASP99
A	ASN101
A	ASP103
A	LYS105
A	GLU107
A	GLU110

---

site_id	AC4
Number of Residues	4
Details	binding site for residue CA A 1004

Chain	Residue
A	LYS105
A	ASP135
A	THR139
A	THR141

---

site_id	AC5
Number of Residues	3
Details	binding site for residue SO4 A 1005

Chain	Residue
A	GLY56
A	GLN57
A	GOL1008

---

site_id	AC6
Number of Residues	5
Details	binding site for residue SO4 A 1006

Chain	Residue
A	THR22
A	ARG23
A	TYR24
A	GLU25
A	MET81

---

site_id	AC7
Number of Residues	4
Details	binding site for residue SO4 A 1007

Chain	Residue
A	GLU107
A	ALA108
A	SER109
A	GLU124

---

site_id	AC8
Number of Residues	6
Details	binding site for residue GOL A 1008

Chain	Residue
A	GLY56
A	GLN57
A	ASP58
A	ALA59
A	SO41005
A	HOH1131

---

site_id	AC9
Number of Residues	6
Details	binding site for residue GOL A 1009

Chain	Residue
A	GLY37
A	ASP76
A	PHE77
A	THR121
A	GLN126
A	ASP173

---

site_id	AD1
Number of Residues	6
Details	binding site for residue CA B 1001

Chain	Residue
B	ASP32
B	ASN34
B	ASP36
B	VAL38
B	GLU43
B	HOH1126

---

site_id	AD2
Number of Residues	6
Details	binding site for residue CA B 1002

Chain	Residue
B	ASP68
B	ASN70
B	ASP72
B	LYS74
B	GLU79
B	HOH1114

---

site_id	AD3
Number of Residues	6
Details	binding site for residue CA B 1003

Chain	Residue
B	ASP99
B	ASN101
B	ASP103
B	LYS105
B	GLU107
B	GLU110

---

site_id	AD4
Number of Residues	3
Details	binding site for residue CA B 1004

Chain	Residue
B	ASP137
B	THR141
B	GLU146

---

site_id	AD5
Number of Residues	3
Details	binding site for residue SO4 B 1005

Chain	Residue
B	GLY56
B	GLN57
B	GOL1009

---

site_id	AD6
Number of Residues	5
Details	binding site for residue SO4 B 1006

Chain	Residue
B	THR22
B	ARG23
B	TYR24
B	GLU25
B	MET81

---

site_id	AD7
Number of Residues	4
Details	binding site for residue SO4 B 1007

Chain	Residue
B	GLU107
B	ALA108
B	SER109
B	GLU124

---

site_id	AD8
Number of Residues	6
Details	binding site for residue GOL B 1008

Chain	Residue
B	GLY37
B	ASP76
B	PHE77
B	GLN126
B	ASP173
B	HOH1118

---

site_id	AD9
Number of Residues	6
Details	binding site for residue GOL B 1009

Chain	Residue
B	GLY56
B	GLN57
B	ASP58
B	ALA59
B	SO41005
B	HOH1124

---

site_id	AE1
Number of Residues	6
Details	binding site for residue CA C 1001

Chain	Residue
C	ASP32
C	ASN34
C	ASP36
C	VAL38
C	GLU43
C	HOH1207

---

site_id	AE2
Number of Residues	5
Details	binding site for residue CA C 1002

Chain	Residue
C	ASP72
C	LYS74
C	GLU79
C	ASP68
C	ASN70

---

site_id	AE3
Number of Residues	6
Details	binding site for residue CA C 1003

Chain	Residue
C	ASP99
C	ASN101
C	ASP103
C	LYS105
C	GLU107
C	GLU110

---

site_id	AE4
Number of Residues	2
Details	binding site for residue CA C 1004

Chain	Residue
C	ASP135
C	THR141

---

site_id	AE5
Number of Residues	4
Details	binding site for residue SO4 C 1005

Chain	Residue
C	GLU107
C	ALA108
C	SER109
C	GLU124

---

site_id	AE6
Number of Residues	3
Details	binding site for residue SO4 C 1006

Chain	Residue
C	GLY56
C	GLN57
C	ASP58

---

site_id	AE7
Number of Residues	6
Details	binding site for residue GOL C 1007

Chain	Residue
C	GLY37
C	ASP76
C	PHE77
C	THR121
C	GLN126
C	ASP173

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DRNGDGVVDigEL

Chain	Residue	Details
A	ASP32-LEU44
A	ASP68-PHE80
A	ASP99-ILE111

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448, ECO:0000269|PubMed:24332718, ECO:0000269|PubMed:26164100, ECO:0007744|PDB:4N5X, ECO:0007744|PDB:4ZCU, ECO:0007744|PDB:4ZCV

Chain	Residue	Details
A	ASP32
A	ASP103
A	LYS105
A	GLU110
B	ASP32
B	ASN34
B	ASP36
B	ASP68
B	ASN70
B	ASP72
B	LYS74
A	ASN34
B	ASP99
B	ASN101
B	ASP103
B	LYS105
B	GLU110
C	ASP32
C	ASN34
C	ASP36
C	ASP68
C	ASN70
A	ASP36
C	ASP72
C	LYS74
C	ASP99
C	ASN101
C	ASP103
C	LYS105
C	GLU110
A	ASP68
A	ASN70
A	ASP72
A	LYS74
A	ASP99
A	ASN101

---

site_id	SWS_FT_FI2
Number of Residues	18
Details	BINDING: BINDING => ECO:0000269|PubMed:24332718, ECO:0000269|PubMed:26164100, ECO:0007744|PDB:4N5X, ECO:0007744|PDB:4ZCU, ECO:0007744|PDB:4ZCV

Chain	Residue	Details
A	VAL38
B	THR139
B	THR141
B	GLU146
C	VAL38
C	ASP135
C	ASP137
C	THR139
C	THR141
C	GLU146
A	ASP135
A	ASP137
A	THR139
A	THR141
A	GLU146
B	VAL38
B	ASP135
B	ASP137

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448, ECO:0000269|PubMed:24332718, ECO:0000269|PubMed:26164100, ECO:0007744|PDB:4ZCU, ECO:0007744|PDB:4ZCV

Chain	Residue	Details
A	GLU43
B	GLU43
C	GLU43

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448, ECO:0000269|PubMed:24332718, ECO:0000269|PubMed:26164100, ECO:0007744|PDB:4N5X, ECO:0007744|PDB:4ZCV

Chain	Residue	Details
A	GLU79
B	GLU79
C	GLU79

---