4ZBB

Crystal structure of the glutathione transferase URE2P8 from Phanerochaete chrysosporium complexed with glutathionyl-S-dinitrobenzene.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004364	molecular_function	glutathione transferase activity
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0016740	molecular_function	transferase activity
B	0004364	molecular_function	glutathione transferase activity
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0016740	molecular_function	transferase activity
C	0004364	molecular_function	glutathione transferase activity
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0016740	molecular_function	transferase activity
D	0004364	molecular_function	glutathione transferase activity
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0016740	molecular_function	transferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	24
Details	binding site for residue GDN A 300

Chain	Residue
A	HIS13
A	GLU74
A	SER75
A	GLY120
A	VAL123
A	TRP176
A	GDN301
A	HOH459
A	HOH460
A	HOH465
A	HOH467
A	SER16
A	HOH478
B	THR113
B	ACT302
B	HOH492
B	HOH526
A	HIS18
A	VAL40
A	GLN45
A	LYS46
A	ARG58
A	THR59
A	PRO60

---

site_id	AC2
Number of Residues	10
Details	binding site for residue GDN A 301

Chain	Residue
A	HIS13
A	ALA15
A	TYR128
A	TRP176
A	MET179
A	PHE183
A	GDN300
A	HOH406
A	HOH471
A	HOH488

---

site_id	AC3
Number of Residues	8
Details	binding site for residue ACT A 302

Chain	Residue
A	TYR118
A	ARG139
A	ACT303
A	HOH466
B	ARG58
B	GLN121
B	GDN300
B	HOH417

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ACT A 303

Chain	Residue
A	ARG139
A	GLU143
A	ACT302
A	HOH542

---

site_id	AC5
Number of Residues	5
Details	binding site for residue CL A 304

Chain	Residue
A	HIS13
A	SER16
A	GLY19
A	THR59
A	PRO60

---

site_id	AC6
Number of Residues	26
Details	binding site for residue GDN C 300

Chain	Residue
C	HIS13
C	SER16
C	HIS18
C	VAL40
C	GLN45
C	LYS46
C	ARG58
C	THR59
C	PRO60
C	GLU74
C	SER75
C	GLY120
C	VAL123
C	TYR128
C	TRP176
C	GDN301
C	HOH431
C	HOH433
C	HOH470
C	HOH503
C	HOH505
C	HOH513
C	HOH517
C	HOH541
D	THR113
D	ACT302

---

site_id	AC7
Number of Residues	13
Details	binding site for residue GDN C 301

Chain	Residue
C	HIS13
C	ALA15
C	TRP124
C	TYR128
C	TRP176
C	MET179
C	PHE183
C	MET220
C	GDN300
C	HOH402
C	HOH489
C	HOH502
C	HOH554

---

site_id	AC8
Number of Residues	6
Details	binding site for residue ACT C 302

Chain	Residue
C	ARG139
C	GLU143
C	ACT304
C	HOH434
C	HOH524
D	GDN300

---

site_id	AC9
Number of Residues	9
Details	binding site for residue GOL C 303

Chain	Residue
C	ASN157
C	HOH407
C	HOH417
C	HOH420
C	HOH425
C	HOH501
A	LYS91
A	ARG206
C	SER156

---

site_id	AD1
Number of Residues	8
Details	binding site for residue ACT C 304

Chain	Residue
C	TYR118
C	ARG139
C	ACT302
D	ARG58
D	GLN121
D	GDN300
D	HOH434
D	HOH509

---

site_id	AD2
Number of Residues	4
Details	binding site for residue CL C 305

Chain	Residue
C	HIS13
C	SER16
C	GLY19
C	THR59

---

site_id	AD3
Number of Residues	24
Details	binding site for residue GDN B 300

Chain	Residue
A	THR113
A	ACT302
A	HOH466
A	HOH482
B	HIS13
B	SER16
B	HIS18
B	VAL40
B	GLN45
B	LYS46
B	ARG58
B	THR59
B	PRO60
B	GLU74
B	SER75
B	GLY120
B	VAL123
B	TRP176
B	GDN301
B	HOH417
B	HOH466
B	HOH494
B	HOH501
B	HOH516

---

site_id	AD4
Number of Residues	19
Details	binding site for residue GDN B 301

Chain	Residue
A	HOH542
B	HIS13
B	LYS14
B	ALA15
B	SER16
B	ALA41
B	TRP124
B	TYR128
B	TRP176
B	MET179
B	PHE183
B	ARG216
B	MET220
B	GDN300
B	HOH434
B	HOH489
B	HOH511
B	HOH530
B	HOH549

---

site_id	AD5
Number of Residues	8
Details	binding site for residue ACT B 302

Chain	Residue
A	ARG58
A	GLN121
A	GDN300
A	HOH460
B	TYR118
B	ARG139
B	ACT303
B	HOH492

---

site_id	AD6
Number of Residues	5
Details	binding site for residue ACT B 303

Chain	Residue
B	ARG139
B	GLU143
B	ACT302
B	HOH418
B	HOH573

---

site_id	AD7
Number of Residues	4
Details	binding site for residue CL B 304

Chain	Residue
B	HIS13
B	SER16
B	GLY19
B	THR59

---

site_id	AD8
Number of Residues	26
Details	binding site for residue GDN D 300

Chain	Residue
C	THR113
C	ACT302
C	ACT304
C	HOH496
D	HIS13
D	SER16
D	HIS18
D	VAL40
D	GLN45
D	LYS46
D	ARG58
D	THR59
D	PRO60
D	GLU74
D	SER75
D	GLY120
D	VAL123
D	TRP176
D	GDN301
D	HOH434
D	HOH467
D	HOH497
D	HOH498
D	HOH500
D	HOH503
D	HOH509

---

site_id	AD9
Number of Residues	15
Details	binding site for residue GDN D 301

Chain	Residue
B	PRO48
B	HOH642
D	HIS13
D	ALA15
D	SER16
D	ALA41
D	TYR128
D	TRP176
D	MET179
D	PHE183
D	GDN300
D	HOH403
D	HOH444
D	HOH490
D	HOH499

---

site_id	AE1
Number of Residues	9
Details	binding site for residue ACT D 302

Chain	Residue
C	ARG58
C	GLY120
C	GLN121
C	GDN300
C	HOH433
C	HOH505
D	TYR118
D	ARG139
D	ACT306

---

site_id	AE2
Number of Residues	6
Details	binding site for residue CL D 303

Chain	Residue
D	LEU12
D	HIS13
D	SER16
D	GLY19
D	THR59
D	PRO60

---

site_id	AE3
Number of Residues	4
Details	binding site for residue ACT D 304

Chain	Residue
C	LYS132
D	ALA95
D	GLU131
D	HOH538

---

site_id	AE4
Number of Residues	7
Details	binding site for residue GOL D 305

Chain	Residue
C	LYS85
C	LYS132
D	GLY97
D	THR98
D	ASP99
D	TYR102
D	HOH516

---

site_id	AE5
Number of Residues	4
Details	binding site for residue ACT D 306

Chain	Residue
D	ARG139
D	GLU143
D	ACT302
D	HOH416

---