4ZAA

Structure of A. niger Fdc1 in complex with 4-vinyl guaiacol

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0009074	biological_process	aromatic amino acid family catabolic process
A	0016829	molecular_function	lyase activity
A	0016831	molecular_function	carboxy-lyase activity
A	0018966	biological_process	styrene metabolic process
A	0030145	molecular_function	manganese ion binding
A	0033494	biological_process	ferulate metabolic process
A	0042537	biological_process	benzene-containing compound metabolic process
A	0042802	molecular_function	identical protein binding
A	0046281	biological_process	cinnamic acid catabolic process
A	0046395	biological_process	carboxylic acid catabolic process
A	0046872	molecular_function	metal ion binding
A	0120254	biological_process	olefinic compound metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	26
Details	binding site for residue 4LU A 601

Chain	Residue
A	THR153
A	SER223
A	SER224
A	MET225
A	PRO226
A	GLU233
A	ILE327
A	LYS391
A	FZZ602
A	MN603
A	K604
A	ASN168
A	4M4606
A	CO2608
A	HOH724
A	HOH726
A	HOH742
A	HOH746
A	HOH747
A	SER170
A	ILE171
A	ALA172
A	ARG173
A	LEU185
A	GLN190
A	HIS191

---

site_id	AC2
Number of Residues	27
Details	binding site for residue FZZ A 602

Chain	Residue
A	THR153
A	ASN168
A	SER170
A	ILE171
A	ALA172
A	ARG173
A	LEU185
A	GLN190
A	HIS191
A	SER223
A	SER224
A	MET225
A	PRO226
A	GLU233
A	THR323
A	ILE327
A	LYS391
A	4LU601
A	MN603
A	K604
A	4M4606
A	CO2608
A	HOH724
A	HOH726
A	HOH740
A	HOH742
A	HOH746

---

site_id	AC3
Number of Residues	8
Details	binding site for residue MN A 603

Chain	Residue
A	ASN168
A	HIS191
A	GLU233
A	4LU601
A	FZZ602
A	K604
A	HOH724
A	HOH816

---

site_id	AC4
Number of Residues	8
Details	binding site for residue K A 604

Chain	Residue
A	TRP169
A	ALA222
A	SER223
A	MET225
A	GLU233
A	4LU601
A	FZZ602
A	MN603

---

site_id	AC5
Number of Residues	6
Details	binding site for residue K A 605

Chain	Residue
A	ARG421
A	ASP427
A	ASP459
A	LEU461
A	HOH1014
A	HOH1077

---

site_id	AC6
Number of Residues	10
Details	binding site for residue 4M4 A 606

Chain	Residue
A	LEU185
A	ILE187
A	GLN190
A	TYR394
A	THR395
A	PHE437
A	LEU439
A	4LU601
A	FZZ602
A	HOH1055

---

site_id	AC7
Number of Residues	10
Details	binding site for residue 4M4 A 607

Chain	Residue
A	ALA6
A	GLU15
A	ALA16
A	VAL19
A	ASP20
A	PRO29
A	ARG86
A	HOH820
A	HOH1027
A	HOH1162

---

site_id	AC8
Number of Residues	5
Details	binding site for residue CO2 A 608

Chain	Residue
A	FZZ602
A	ARG173
A	MET283
A	LEU439
A	4LU601

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_03196","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"26083754","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03196","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"26083754","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03196","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---