4Z6Y

Structure of the TBC1D7-TSC1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005096	molecular_function	GTPase activator activity
A	0005515	molecular_function	protein binding
A	0005765	cellular_component	lysosomal membrane
A	0005829	cellular_component	cytosol
A	0009267	biological_process	cellular response to starvation
A	0031267	molecular_function	small GTPase binding
A	0031398	biological_process	positive regulation of protein ubiquitination
A	0031410	cellular_component	cytoplasmic vesicle
A	0032007	biological_process	negative regulation of TOR signaling
A	0033596	cellular_component	TSC1-TSC2 complex
A	0036064	cellular_component	ciliary basal body
A	0043547	biological_process	positive regulation of GTPase activity
A	0062078	molecular_function	TSC1-TSC2 complex binding
A	0070848	biological_process	response to growth factor
A	0090630	biological_process	activation of GTPase activity
A	1902018	biological_process	negative regulation of cilium assembly
A	1904262	biological_process	negative regulation of TORC1 signaling
B	0005096	molecular_function	GTPase activator activity
B	0005515	molecular_function	protein binding
B	0005765	cellular_component	lysosomal membrane
B	0005829	cellular_component	cytosol
B	0009267	biological_process	cellular response to starvation
B	0031267	molecular_function	small GTPase binding
B	0031398	biological_process	positive regulation of protein ubiquitination
B	0031410	cellular_component	cytoplasmic vesicle
B	0032007	biological_process	negative regulation of TOR signaling
B	0033596	cellular_component	TSC1-TSC2 complex
B	0036064	cellular_component	ciliary basal body
B	0043547	biological_process	positive regulation of GTPase activity
B	0062078	molecular_function	TSC1-TSC2 complex binding
B	0070848	biological_process	response to growth factor
B	0090630	biological_process	activation of GTPase activity
B	1902018	biological_process	negative regulation of cilium assembly
B	1904262	biological_process	negative regulation of TORC1 signaling
E	0005096	molecular_function	GTPase activator activity
E	0005515	molecular_function	protein binding
E	0005765	cellular_component	lysosomal membrane
E	0005829	cellular_component	cytosol
E	0009267	biological_process	cellular response to starvation
E	0031267	molecular_function	small GTPase binding
E	0031398	biological_process	positive regulation of protein ubiquitination
E	0031410	cellular_component	cytoplasmic vesicle
E	0032007	biological_process	negative regulation of TOR signaling
E	0033596	cellular_component	TSC1-TSC2 complex
E	0036064	cellular_component	ciliary basal body
E	0043547	biological_process	positive regulation of GTPase activity
E	0062078	molecular_function	TSC1-TSC2 complex binding
E	0070848	biological_process	response to growth factor
E	0090630	biological_process	activation of GTPase activity
E	1902018	biological_process	negative regulation of cilium assembly
E	1904262	biological_process	negative regulation of TORC1 signaling
G	0005096	molecular_function	GTPase activator activity
G	0005515	molecular_function	protein binding
G	0005765	cellular_component	lysosomal membrane
G	0005829	cellular_component	cytosol
G	0009267	biological_process	cellular response to starvation
G	0031267	molecular_function	small GTPase binding
G	0031398	biological_process	positive regulation of protein ubiquitination
G	0031410	cellular_component	cytoplasmic vesicle
G	0032007	biological_process	negative regulation of TOR signaling
G	0033596	cellular_component	TSC1-TSC2 complex
G	0036064	cellular_component	ciliary basal body
G	0043547	biological_process	positive regulation of GTPase activity
G	0062078	molecular_function	TSC1-TSC2 complex binding
G	0070848	biological_process	response to growth factor
G	0090630	biological_process	activation of GTPase activity
G	1902018	biological_process	negative regulation of cilium assembly
G	1904262	biological_process	negative regulation of TORC1 signaling

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	724
Details	Domain: {"description":"Rab-GAP TBC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00163","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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