4Z68

Hybrid structural analysis of the Arp2/3 regulator Arpin identifies its acidic tail as a primary binding epitope

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
A	0016055	biological_process	Wnt signaling pathway
A	0032212	biological_process	positive regulation of telomere maintenance via telomerase
A	0051225	biological_process	spindle assembly

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue SO4 A 701

Chain	Residue
A	ASN537
A	ARG538
A	VAL539
A	SER540
A	LYS557
A	HOH802
A	HOH814

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site_id	AC2
Number of Residues	4
Details	binding site for residue SO4 A 702

Chain	Residue
A	HIS614
A	ARG623
A	GLU576
A	LYS592

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: (3S)-3-hydroxyasparagine; by HIF1AN; partial => ECO:0000269|PubMed:18936059

Chain	Residue	Details
A	ASN518
A	ASN586

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: (3S)-3-hydroxyhistidine; by HIF1AN; partial => ECO:0000269|PubMed:21251231

Chain	Residue	Details
A	HIS553

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