4Z43
Crystal structure of Tryptophan 7-halogenase (PrnA) Mutant E450K
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 32 |
| Details | binding site for residue FAD A 601 |
| Chain | Residue |
| A | GLY12 |
| A | VAL47 |
| A | GLY48 |
| A | ALA50 |
| A | GLU186 |
| A | VAL187 |
| A | CYS217 |
| A | SER218 |
| A | GLY219 |
| A | ARG221 |
| A | LEU223 |
| A | GLY13 |
| A | GLY336 |
| A | LEU337 |
| A | PHE341 |
| A | PRO344 |
| A | GLY349 |
| A | ILE350 |
| A | CL603 |
| A | HOH703 |
| A | HOH705 |
| A | HOH714 |
| A | GLY14 |
| A | HOH715 |
| A | HOH738 |
| A | HOH742 |
| A | THR15 |
| A | ALA16 |
| A | SER39 |
| A | ILE42 |
| A | ARG44 |
| A | ILE45 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 602 |
| Chain | Residue |
| A | MET236 |
| A | ARG323 |
| A | ASP386 |
| A | ARG389 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 603 |
| Chain | Residue |
| A | PRO344 |
| A | SER347 |
| A | THR348 |
| A | GLY349 |
| A | FAD601 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"16195462","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16195462","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18979475","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2APG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AQJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AR8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JKC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16195462","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2APG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AR8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16195462","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2APG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AQJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AR8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16195462","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2AR8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16195462","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2AQJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16195462","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18979475","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2AQJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JKC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Site: {"description":"Role in guiding and activating HOCl"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for activity","evidences":[{"source":"PubMed","id":"16195462","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"18979475","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
