Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004097 | molecular_function | catechol oxidase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0004097 | molecular_function | catechol oxidase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CU A 601 |
| Chain | Residue |
| A | HIS96 |
| A | HIS119 |
| A | HIS128 |
| A | CU602 |
| A | O603 |
| A | O604 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CU A 602 |
| Chain | Residue |
| A | CU601 |
| A | O603 |
| A | O604 |
| A | HIS255 |
| A | HIS259 |
| A | HIS289 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue O A 603 |
| Chain | Residue |
| A | HIS96 |
| A | HIS119 |
| A | HIS128 |
| A | HIS259 |
| A | PHE276 |
| A | PHE285 |
| A | HIS289 |
| A | CU601 |
| A | CU602 |
| A | O604 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue O A 604 |
| Chain | Residue |
| A | HIS119 |
| A | PHE124 |
| A | HIS128 |
| A | HIS255 |
| A | HIS289 |
| A | CU601 |
| A | CU602 |
| A | O603 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 605 |
| Chain | Residue |
| A | VAL247 |
| A | SER249 |
| A | ALA252 |
| A | GLY455 |
| A | ALA473 |
| A | ARG474 |
| A | HOH780 |
| A | HOH874 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 606 |
| Chain | Residue |
| A | ASP181 |
| A | ASN183 |
| A | HIS184 |
| A | TYR194 |
| A | GLY196 |
| A | LYS197 |
| A | ASP198 |
| A | HOH732 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | binding site for residue TEW A 607 |
| Chain | Residue |
| A | LYS62 |
| A | LYS154 |
| A | GLU157 |
| A | PRO158 |
| A | LYS159 |
| A | ASN350 |
| A | LYS352 |
| A | PRO356 |
| A | HOH733 |
| A | HOH776 |
| A | HOH803 |
| A | HOH849 |
| A | HOH857 |
| A | HOH950 |
| A | HOH965 |
| A | HOH1000 |
| B | LYS52 |
| B | LYS53 |
| B | PRO202 |
| B | ASP203 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue TEW A 608 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue W A 609 |
| Chain | Residue |
| B | W606 |
| B | W607 |
| B | TE611 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue CU B 601 |
| Chain | Residue |
| B | HIS96 |
| B | HIS119 |
| B | HIS128 |
| B | CU602 |
| B | O603 |
| B | O604 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue CU B 602 |
| Chain | Residue |
| B | HIS255 |
| B | HIS259 |
| B | HIS289 |
| B | CU601 |
| B | O603 |
| B | O604 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue O B 603 |
| Chain | Residue |
| B | HIS96 |
| B | HIS255 |
| B | HIS259 |
| B | PHE276 |
| B | PHE285 |
| B | HIS289 |
| B | CU601 |
| B | CU602 |
| B | O604 |
| site_id | AD4 |
| Number of Residues | 9 |
| Details | binding site for residue O B 604 |
| Chain | Residue |
| B | CU602 |
| B | O603 |
| B | HIS96 |
| B | HIS119 |
| B | PHE124 |
| B | HIS128 |
| B | HIS255 |
| B | HIS289 |
| B | CU601 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 605 |
| Chain | Residue |
| B | VAL247 |
| B | SER249 |
| B | ALA252 |
| B | GLY455 |
| B | ALA473 |
| B | ARG474 |
| B | PHE475 |
| B | HOH839 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue W B 606 |
| Chain | Residue |
| A | W609 |
| B | W610 |
| B | TE611 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue W B 607 |
| Chain | Residue |
| A | W609 |
| B | W608 |
| B | TE611 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue W B 608 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue W B 609 |
| Chain | Residue |
| B | ASN350 |
| B | W610 |
| B | W612 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue W B 610 |
| Chain | Residue |
| B | ASN350 |
| B | W606 |
| B | W609 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue TE B 611 |
| Chain | Residue |
| A | W609 |
| B | W606 |
| B | W607 |
| B | W608 |
| B | W612 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue W B 612 |
| Chain | Residue |
| B | LYS62 |
| B | LYS159 |
| B | W609 |
| B | TE611 |
| site_id | AE4 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide CYS B 100 and HIS B 119 |
| Chain | Residue |
| B | HIS96 |
| B | CYS97 |
| B | ALA98 |
| B | TYR99 |
| B | ASN101 |
| B | GLY102 |
| B | GLN117 |
| B | ILE118 |
| B | ASN120 |
| B | SER121 |
| B | HIS128 |
| B | GLU251 |
| B | PHE276 |
| B | CU601 |
| B | O604 |
| B | HOH817 |
| B | HOH973 |
Functional Information from PROSITE/UniProt
| site_id | PS00497 |
| Number of Residues | 18 |
| Details | TYROSINASE_1 Tyrosinase CuA-binding region signature. Hnswl.FFpFHRwyLyfyE |
| Chain | Residue | Details |
| A | HIS119-GLU136 | |
| site_id | PS00498 |
| Number of Residues | 12 |
| Details | TYROSINASE_2 Tyrosinase and hemocyanins CuB-binding region signature. DPvFYihHanvD |
| Chain | Residue | Details |
| A | ASP282-ASP293 | |
