Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004097 | molecular_function | catechol oxidase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0004097 | molecular_function | catechol oxidase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| C | 0004097 | molecular_function | catechol oxidase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| D | 0004097 | molecular_function | catechol oxidase activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| E | 0004097 | molecular_function | catechol oxidase activity |
| E | 0016491 | molecular_function | oxidoreductase activity |
| F | 0004097 | molecular_function | catechol oxidase activity |
| F | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue CU A 601 |
| Chain | Residue |
| A | HIS93 |
| A | CYS97 |
| A | HIS116 |
| A | HIS125 |
| A | HS8252 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue RCO A 602 |
| Chain | Residue |
| C | ALA73 |
| C | ARG76 |
| C | PRO171 |
| C | HOH786 |
| A | ALA73 |
| A | ARG76 |
| A | ALA168 |
| A | HOH702 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue RCO A 603 |
| Chain | Residue |
| A | GLY303 |
| A | HOH718 |
| A | HOH839 |
| D | ASP221 |
| D | GLY303 |
| D | VAL305 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue RCO A 604 |
| Chain | Residue |
| A | GLN202 |
| A | HOH751 |
| A | HOH814 |
| C | LEU208 |
| G | THR442 |
| G | PRO444 |
| G | TYR449 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 605 |
| Chain | Residue |
| A | ASP178 |
| A | HIS181 |
| A | TYR191 |
| A | GLY193 |
| A | ASP195 |
| A | HOH723 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue CU B 601 |
| Chain | Residue |
| B | HIS93 |
| B | CYS97 |
| B | HIS116 |
| B | HIS125 |
| B | HS8252 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue RCO B 602 |
| Chain | Residue |
| B | GLN201 |
| B | VAL204 |
| B | LEU208 |
| D | SER209 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue RCO B 603 |
| Chain | Residue |
| B | PRO302 |
| B | GLY303 |
| B | GOL604 |
| B | HOH760 |
| F | ASP221 |
| F | GLY303 |
| F | VAL305 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 604 |
| Chain | Residue |
| B | ILE307 |
| B | THR308 |
| B | ASP309 |
| B | RCO603 |
| B | HOH810 |
| F | VAL220 |
| F | PRO302 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 605 |
| Chain | Residue |
| B | ASP42 |
| B | PHE43 |
| B | GLN44 |
| B | TYR130 |
| B | ASP321 |
| B | HOH707 |
| B | HOH737 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 606 |
| Chain | Residue |
| B | PHE43 |
| B | LYS332 |
| B | ASP333 |
| B | HOH903 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue CU C 601 |
| Chain | Residue |
| C | HIS93 |
| C | CYS97 |
| C | HIS116 |
| C | HIS125 |
| C | HS8252 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue RCO C 602 |
| Chain | Residue |
| A | GLN201 |
| A | VAL204 |
| C | SER209 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue RCO C 603 |
| Chain | Residue |
| C | ASP221 |
| C | GLY303 |
| C | VAL305 |
| C | HOH709 |
| C | HOH734 |
| E | ASP221 |
| E | PRO302 |
| E | GLY303 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue GOL C 604 |
| Chain | Residue |
| A | HOH789 |
| C | TYR212 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 605 |
| Chain | Residue |
| C | GLN44 |
| C | TYR130 |
| C | ASP321 |
| C | HOH705 |
| C | HOH749 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue CU D 601 |
| Chain | Residue |
| D | HIS93 |
| D | CYS97 |
| D | HIS116 |
| D | HIS125 |
| D | HS8252 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue RCO D 602 |
| Chain | Residue |
| B | TYR212 |
| B | LEU215 |
| D | TYR212 |
| D | HOH830 |
| site_id | AE1 |
| Number of Residues | 10 |
| Details | binding site for residue RCO D 603 |
| Chain | Residue |
| B | ARG76 |
| B | ALA168 |
| B | SER169 |
| B | PRO171 |
| D | ALA73 |
| D | ALA168 |
| D | SER169 |
| D | HOH703 |
| D | HOH725 |
| B | ALA73 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 604 |
| Chain | Residue |
| B | ALA77 |
| D | ARG27 |
| D | ARG76 |
| D | ASP174 |
| D | GLN175 |
| D | TYR278 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue CU E 601 |
| Chain | Residue |
| E | HIS93 |
| E | CYS97 |
| E | HIS116 |
| E | HIS125 |
| E | HS8252 |
| site_id | AE4 |
| Number of Residues | 7 |
| Details | binding site for residue RCO E 602 |
| Chain | Residue |
| E | GLN202 |
| E | HOH731 |
| F | PRO155 |
| F | LEU208 |
| K | THR442 |
| K | PRO444 |
| K | TYR449 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue RCO E 603 |
| Chain | Residue |
| E | GLN201 |
| E | VAL204 |
| F | ALA205 |
| F | LEU208 |
| F | SER209 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue ACT K 501 |
| Chain | Residue |
| F | ARG291 |
| F | GLU346 |
| K | GLY439 |
| K | THR442 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue CU F 700 |
| Chain | Residue |
| F | HIS93 |
| F | CYS97 |
| F | HIS116 |
| F | HIS125 |
| F | HS8252 |
| site_id | AE8 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide CYS B 97 and HIS B 116 |
| Chain | Residue |
| B | HIS93 |
| B | CYS94 |
| B | ALA95 |
| B | TYR96 |
| B | ASN98 |
| B | GLY99 |
| B | GLN114 |
| B | ILE115 |
| B | ASN117 |
| B | SER118 |
| B | HIS125 |
| B | GLU248 |
| B | HS8252 |
| B | PHE273 |
| B | CU601 |
| B | HOH716 |
| B | HOH758 |
| site_id | AE9 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide CYS C 97 and HIS C 116 |
| Chain | Residue |
| C | HIS93 |
| C | CYS94 |
| C | ALA95 |
| C | TYR96 |
| C | ASN98 |
| C | GLY99 |
| C | GLN114 |
| C | ILE115 |
| C | ASN117 |
| C | SER118 |
| C | HIS125 |
| C | GLU248 |
| C | HS8252 |
| C | PHE273 |
| C | CU601 |
| C | HOH724 |
| C | HOH825 |
| site_id | AF1 |
| Number of Residues | 16 |
| Details | binding site for Di-peptide CYS D 97 and HIS D 116 |
| Chain | Residue |
| D | HIS93 |
| D | CYS94 |
| D | ALA95 |
| D | TYR96 |
| D | ASN98 |
| D | GLN114 |
| D | ILE115 |
| D | ASN117 |
| D | SER118 |
| D | HIS125 |
| D | GLU248 |
| D | HS8252 |
| D | PHE273 |
| D | CU601 |
| D | HOH741 |
| D | HOH797 |
| site_id | AF2 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide CYS E 97 and HIS E 116 |
| Chain | Residue |
| E | HIS93 |
| E | CYS94 |
| E | ALA95 |
| E | TYR96 |
| E | ASN98 |
| E | GLN114 |
| E | ILE115 |
| E | ASN117 |
| E | SER118 |
| E | HIS125 |
| E | GLU248 |
| E | HS8252 |
| E | PHE273 |
| E | CU601 |
| E | HOH712 |
| E | HOH756 |
| E | HOH886 |
| site_id | AF3 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide CYS F 97 and HIS F 116 |
| Chain | Residue |
| F | HIS93 |
| F | CYS94 |
| F | ALA95 |
| F | TYR96 |
| F | ASN98 |
| F | GLY99 |
| F | GLN114 |
| F | ILE115 |
| F | ASN117 |
| F | SER118 |
| F | HIS125 |
| F | GLU248 |
| F | HS8252 |
| F | PHE273 |
| F | CU700 |
| F | HOH812 |
| F | HOH864 |
| F | HOH916 |
Functional Information from PROSITE/UniProt
| site_id | PS00497 |
| Number of Residues | 18 |
| Details | TYROSINASE_1 Tyrosinase CuA-binding region signature. Hnswl.FFpFHRwyLyfyE |
| Chain | Residue | Details |
| A | HIS116-GLU133 | |
| site_id | PS00498 |
| Number of Residues | 12 |
| Details | TYROSINASE_2 Tyrosinase and hemocyanins CuB-binding region signature. DPvFYihHanvD |
| Chain | Residue | Details |
| A | ASP279-ASP290 | |
