Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005764 | cellular_component | lysosome |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| A | 0051603 | biological_process | proteolysis involved in protein catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | GLY20 |
| A | LYS21 |
| A | CYS22 |
| A | ARG81 |
| A | ALA93 |
| A | ARG94 |
| A | THR104 |
| A | HOH448 |
| A | HOH581 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | LEU1 |
| A | LEU1 |
| A | LYS125 |
| A | LYS125 |
| A | HOH434 |
| A | HOH493 |
| A | HOH493 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | LYS39 |
| A | THR44 |
| A | LEU45 |
| A | HOH433 |
| A | HOH547 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | ASP71 |
| A | TYR113 |
| A | ASP115 |
| A | HOH411 |
| A | HOH565 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 305 |
| Chain | Residue |
| A | ASP55 |
| A | ASP62 |
| A | LYS95 |
| A | ALA97 |
| A | CYS98 |
| A | HOH515 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 306 |
| Chain | Residue |
| A | PRO2 |
| A | GLU3 |
| A | THR4 |
| A | HOH431 |
| A | HOH486 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 307 |
| Chain | Residue |
| A | ASP18 |
| A | ASP18 |
| A | GLY185 |
| A | THR186 |
| A | HOH465 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 308 |
| Chain | Residue |
| A | PRO117 |
| A | ALA118 |
| A | HOH419 |
| A | HOH459 |
| A | HOH474 |
| A | HOH511 |
| A | HOH600 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | binding site for Ligand residues SCH A 25 through TRP A 26 bound to SER A 24 |
| Chain | Residue |
| A | GLN19 |
| A | GLY23 |
| A | SER24 |
| A | VAL27 |
| A | PHE28 |
| A | SER29 |
| A | VAL30 |
| A | LEU53 |
| A | PRO58 |
| A | SER59 |
| A | GLY64 |
| A | GLY67 |
| A | GLY68 |
| A | MET70 |
| A | HIS162 |
| A | ALA163 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGkCGSCWVfSV |
| Chain | Residue | Details |
| A | GLN19-VAL30 | |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. NDHAVVVVGYG |
| Chain | Residue | Details |
| A | ASN160-GLY170 | |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWLvRNSWgtkWGeeGYMkL |
| Chain | Residue | Details |
| A | TYR177-LEU196 | |
