Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005764 | cellular_component | lysosome |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| A | 0051603 | biological_process | proteolysis involved in protein catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | SCH25 |
| A | TRP26 |
| A | GLY67 |
| A | GLY68 |
| A | HIS162 |
| A | ALA163 |
| A | HOH471 |
| A | HOH521 |
| A | HOH522 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | SER112 |
| A | GLU114 |
| A | GLY141 |
| A | ARG142 |
| A | HOH468 |
| A | HOH476 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | GLY150 |
| A | GLU172 |
| A | GLU190 |
| A | LYS195 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | ILE16 |
| A | ARG17 |
| A | ASN18 |
| A | ASN18 |
| A | GLY185 |
| A | GLY185 |
| A | THR186 |
| A | THR186 |
| A | HOH446 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 305 |
| Chain | Residue |
| A | TRP69 |
| A | GLN105 |
| A | HOH448 |
| A | HOH487 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue 16P A 306 |
| Chain | Residue |
| A | ASN18 |
| A | ASN18 |
| A | GLY20 |
| A | GLY20 |
| A | ARG21 |
| A | ARG21 |
| A | TYR91 |
| A | TRP184 |
| site_id | AC7 |
| Number of Residues | 19 |
| Details | binding site for Ligand residues SCH A 25 through TRP A 26 bound to SER A 24 |
| Chain | Residue |
| A | GLN19 |
| A | GLY23 |
| A | SER24 |
| A | ALA27 |
| A | PHE28 |
| A | SER29 |
| A | VAL30 |
| A | LEU53 |
| A | SER59 |
| A | GLY64 |
| A | GLY67 |
| A | GLY68 |
| A | HIS162 |
| A | ALA163 |
| A | VAL164 |
| A | ASN182 |
| A | SER183 |
| A | TRP184 |
| A | SO4301 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGrCGSCWAfSV |
| Chain | Residue | Details |
| A | GLN19-VAL30 | |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. LDHAVVAIGYG |
| Chain | Residue | Details |
| A | LEU160-GLY170 | |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWLvRNSWgtnWGerGYIkL |
| Chain | Residue | Details |
| A | TYR177-LEU196 | |
