4YWS

Thermostable enolase from Chloroflexus aurantiacus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000015	cellular_component	phosphopyruvate hydratase complex
A	0000287	molecular_function	magnesium ion binding
A	0004634	molecular_function	phosphopyruvate hydratase activity
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0006096	biological_process	glycolytic process
A	0009986	cellular_component	cell surface
A	0016829	molecular_function	lyase activity
A	0046872	molecular_function	metal ion binding
B	0000015	cellular_component	phosphopyruvate hydratase complex
B	0000287	molecular_function	magnesium ion binding
B	0004634	molecular_function	phosphopyruvate hydratase activity
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0006096	biological_process	glycolytic process
B	0009986	cellular_component	cell surface
B	0016829	molecular_function	lyase activity
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue MG A 501

Chain	Residue
A	ASP243
A	GLU286
A	ASP313
A	LYS389
A	HOH623
A	HOH641
A	HOH649

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site_id	AC2
Number of Residues	4
Details	binding site for residue MG B 501

Chain	Residue
B	ASP313
B	HOH601
B	ASP243
B	GLU286

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Functional Information from PROSITE/UniProt

site_id	PS00164
Number of Residues	14
Details	ENOLASE Enolase signature. ILIKlNQIGSLTET

Chain	Residue	Details
A	ILE335-THR348

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00318

Chain	Residue	Details
A	GLU206
B	GLU206

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00318

Chain	Residue	Details
A	LYS338
B	LYS338

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site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0007744|PDB:4Z17

Chain	Residue	Details
A	GLY41
A	ASP313
A	ARG367
A	LYS389
B	GLY41
B	ASP313
B	ARG367
B	LYS389

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site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:26082925

Chain	Residue	Details
A	SER43
B	SER43

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site_id	SWS_FT_FI5
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:26082925, ECO:0007744|PDB:4Z17

Chain	Residue	Details
A	GLU165
A	LYS338
A	SER368
B	GLU165
B	LYS338
B	SER368

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site_id	SWS_FT_FI6
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:26082925, ECO:0007744|PDB:4Z1Y

Chain	Residue	Details
A	GLU206
B	GLU206

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site_id	SWS_FT_FI7
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00318, ECO:0000269|PubMed:26082925, ECO:0007744|PDB:4YWS, ECO:0007744|PDB:4Z17, ECO:0007744|PDB:4Z1Y

Chain	Residue	Details
A	ASP243
A	GLU286
B	ASP243
B	GLU286

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