4YWE
Crystal Structure of a Putative Aldehyde Dehydrogenase from Burkholderia cenocepacia
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| H | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | THR39 |
| A | ALA40 |
| A | GLU208 |
| A | HOH871 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 502 |
| Chain | Residue |
| A | GLY452 |
| A | GLY455 |
| A | HOH891 |
| B | HIS242 |
| B | HOH722 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 503 |
| Chain | Residue |
| A | VAL24 |
| A | ASP91 |
| A | ASP177 |
| A | HOH814 |
| A | HOH829 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 504 |
| Chain | Residue |
| A | HIS242 |
| A | HOH797 |
| B | GLY452 |
| B | GLY455 |
| B | HOH949 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 501 |
| Chain | Residue |
| B | GLU65 |
| B | ARG72 |
| B | HOH725 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 502 |
| Chain | Residue |
| A | ARG426 |
| B | GLU138 |
| B | HOH630 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 503 |
| Chain | Residue |
| B | VAL24 |
| B | ASP91 |
| B | ASP177 |
| B | HOH735 |
| B | HOH756 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 501 |
| Chain | Residue |
| C | GLY206 |
| C | GLY210 |
| C | ALA211 |
| C | VAL234 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 502 |
| Chain | Residue |
| C | VAL245 |
| C | HOH614 |
| D | PRO244 |
| D | VAL245 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue MG C 503 |
| Chain | Residue |
| C | PRO217 |
| C | HOH685 |
| C | HOH839 |
| C | HOH852 |
| C | HOH926 |
| C | HOH950 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue CA C 504 |
| Chain | Residue |
| C | VAL24 |
| C | ASP91 |
| C | ASP177 |
| C | HOH755 |
| C | HOH854 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue CA D 501 |
| Chain | Residue |
| B | HOH675 |
| B | HOH790 |
| B | HOH842 |
| D | ASP338 |
| D | ASP342 |
| D | HOH619 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue CA D 502 |
| Chain | Residue |
| D | VAL24 |
| D | ASP91 |
| D | ASP177 |
| D | HOH744 |
| D | HOH826 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue MG E 501 |
| Chain | Residue |
| E | PRO217 |
| E | HOH784 |
| E | HOH875 |
| E | HOH935 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue CA E 502 |
| Chain | Residue |
| E | VAL24 |
| E | ASP91 |
| E | ASP177 |
| E | HOH672 |
| E | HOH836 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO F 501 |
| Chain | Residue |
| F | ASN325 |
| F | ALA326 |
| F | LYS327 |
| F | PHE361 |
| F | HOH801 |
| F | HOH839 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO F 502 |
| Chain | Residue |
| F | ALA400 |
| F | HOH848 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO F 503 |
| Chain | Residue |
| F | SER62 |
| F | HOH764 |
| G | GLU445 |
| G | HOH682 |
| H | GLN128 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue CA F 504 |
| Chain | Residue |
| F | ASP338 |
| F | ASP342 |
| F | HOH613 |
| F | HOH627 |
| H | HOH772 |
| H | HOH848 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue CA F 505 |
| Chain | Residue |
| F | VAL24 |
| F | ASP91 |
| F | ASP177 |
| F | HOH778 |
| F | HOH819 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO G 501 |
| Chain | Residue |
| G | PRO244 |
| G | VAL245 |
| G | HOH605 |
| G | HOH743 |
| H | VAL245 |
| H | HIS456 |
| site_id | AE4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO G 502 |
| Chain | Residue |
| G | ALA4 |
| G | ALA33 |
| G | THR34 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO G 503 |
| Chain | Residue |
| G | ARG51 |
| G | ASP220 |
| G | HOH708 |
| G | HOH759 |
| G | HOH837 |
| H | ARG429 |
| H | EDO501 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO G 504 |
| Chain | Residue |
| G | ALA212 |
| G | ARG215 |
| G | HOH684 |
| site_id | AE7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO G 505 |
| Chain | Residue |
| G | GLN363 |
| G | ALA364 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue CA G 506 |
| Chain | Residue |
| G | VAL24 |
| G | ASP91 |
| G | ASP177 |
| G | HOH749 |
| G | HOH796 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue CA G 507 |
| Chain | Residue |
| G | HIS242 |
| G | HOH760 |
| H | GLY452 |
| H | GLY455 |
| H | HOH919 |
| site_id | AF1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO H 501 |
| Chain | Residue |
| G | EDO503 |
| H | ASN403 |
| H | THR405 |
| H | PRO406 |
| H | TYR407 |
| H | ARG429 |
| H | GLY452 |
| H | HOH608 |
| site_id | AF2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO H 502 |
| Chain | Residue |
| H | LEU14 |
| H | LEU18 |
| H | HOH669 |
| H | HOH868 |
| site_id | AF3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO H 503 |
| Chain | Residue |
| H | SER62 |
| H | GLU65 |
| H | ARG68 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO H 504 |
| Chain | Residue |
| H | ILE155 |
| H | ARG158 |
| H | LYS460 |
| H | HOH628 |
| H | HOH825 |
| site_id | AF5 |
| Number of Residues | 5 |
| Details | binding site for residue CA H 505 |
| Chain | Residue |
| H | VAL24 |
| H | ASP91 |
| H | ASP177 |
| H | HOH737 |
| H | HOH853 |
Functional Information from PROSITE/UniProt
| site_id | PS00070 |
| Number of Residues | 12 |
| Details | ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. VqNGGQTCSAGS |
| Chain | Residue | Details |
| A | VAL275-SER286 |
| site_id | PS00687 |
| Number of Residues | 8 |
| Details | ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. LELGGKSP |
| Chain | Residue | Details |
| A | LEU247-PRO254 |
