Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004623 | molecular_function | A2-type glycerophospholipase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005543 | molecular_function | phospholipid binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006644 | biological_process | phospholipid metabolic process |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0042130 | biological_process | negative regulation of T cell proliferation |
| A | 0050482 | biological_process | arachidonate secretion |
| A | 0090729 | molecular_function | toxin activity |
| B | 0004623 | molecular_function | A2-type glycerophospholipase activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0005543 | molecular_function | phospholipid binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006644 | biological_process | phospholipid metabolic process |
| B | 0016042 | biological_process | lipid catabolic process |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0042130 | biological_process | negative regulation of T cell proliferation |
| B | 0050482 | biological_process | arachidonate secretion |
| B | 0090729 | molecular_function | toxin activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue PE4 B 201 |
| Chain | Residue |
| A | PRO113 |
| B | GLY6 |
| B | PRO17 |
| B | TYR21 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue PE4 B 202 |
| Chain | Residue |
| B | TRP68 |
| B | PHE3 |
| B | LYS7 |
| B | LEU10 |
| B | GLN11 |
| B | TYR66 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue DHC B 203 |
| Chain | Residue |
| A | LEU111 |
| B | LYS15 |
| B | ASN16 |
| B | PRO80 |
| B | HOH307 |
| B | HOH314 |
| B | HOH357 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue DHC B 204 |
| Chain | Residue |
| B | LYS19 |
| B | THR55 |
| B | LYS105 |
| B | ARG108 |
| B | HOH307 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue PE4 A 201 |
| Chain | Residue |
| A | LEU2 |
| A | GLY6 |
| A | PRO17 |
| A | TYR21 |
| A | HOH307 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 202 |
| Chain | Residue |
| A | GLY32 |
| A | ARG33 |
| A | LYS52 |
| A | HOH343 |
| A | HOH346 |
| A | HOH364 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue DHC A 203 |
| Chain | Residue |
| A | THR72 |
| A | ILE94 |
| A | ARG97 |
| A | GLU98 |
| A | HOH303 |
| A | HOH309 |
| A | HOH359 |
| B | LYS35 |
| B | PRO36 |
| B | ARG42 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue DHC A 204 |
| Chain | Residue |
| A | LYS15 |
| A | LYS19 |
| A | LYS105 |
| A | ARG108 |
| A | HOH301 |
| A | HOH370 |
| B | THR55 |
| B | GLY56 |
Functional Information from PROSITE/UniProt
| site_id | PS00118 |
| Number of Residues | 8 |
| Details | PA2_HIS Phospholipase A2 histidine active site. CCYvHKcC |
| Chain | Residue | Details |
| B | CYS43-CYS50 | |
| site_id | PS00119 |
| Number of Residues | 11 |
| Details | PA2_ASP Phospholipase A2 aspartic acid active site. LCECDKAVaIC |
| Chain | Residue | Details |
| B | LEU85-CYS95 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Region: {"description":"Important for membrane-damaging activities in eukaryotes and bacteria; heparin-binding","evidences":[{"source":"UniProtKB","id":"P24605","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Site: {"description":"Important residue of the cationic membrane-docking site (MDoS)","evidences":[{"source":"UniProtKB","id":"I6L8L6","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Site: {"description":"Hydrophobic membrane-disruption site (MDiS)","evidences":[{"source":"UniProtKB","id":"I6L8L6","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Site: {"description":"Cationic membrane-docking site (MDoS)","evidences":[{"source":"UniProtKB","id":"I6L8L6","evidenceCode":"ECO:0000250"}]} |
