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4YP2

Cleavage of nicotinamide adenine dinucleotides by the ribosome inactivating protein from Momordica charantia

Functional Information from GO Data
ChainGOidnamespacecontents
B0006952biological_processdefense response
B0016787molecular_functionhydrolase activity
B0017148biological_processnegative regulation of translation
B0030598molecular_functionrRNA N-glycosylase activity
B0035821biological_processmodulation of process of another organism
B0090729molecular_functiontoxin activity
Functional Information from PROSITE/UniProt
site_idPS00275
Number of Residues17
DetailsSHIGA_RICIN Shiga/ricin ribosomal inactivating toxins active site signature. IqTTaEAARFKyIEqqI
ChainResidueDetails
BILE155-ILE171

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE:
ChainResidueDetails
BGLU160

site_idSWS_FT_FI2
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine
ChainResidueDetails
BASN227

Catalytic Information from CSA
site_idMCSA1
Number of Residues3
DetailsM-CSA 825
ChainResidueDetails
BILE71electrostatic stabiliser, hydrogen bond donor
BGLU160electrostatic stabiliser
BARG163activator, electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

226707

PDB entries from 2024-10-30

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