Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004807 | molecular_function | triose-phosphate isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006094 | biological_process | gluconeogenesis |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0019563 | biological_process | glycerol catabolic process |
| A | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
| B | 0004807 | molecular_function | triose-phosphate isomerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006094 | biological_process | gluconeogenesis |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0019563 | biological_process | glycerol catabolic process |
| B | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue 13P A 301 |
| Chain | Residue |
| A | ASN10 |
| A | GLY238 |
| A | GLY239 |
| A | SO4302 |
| A | HOH451 |
| A | HOH456 |
| A | HOH537 |
| A | HOH548 |
| A | HOH551 |
| A | HOH552 |
| A | LYS12 |
| A | HIS97 |
| A | GLU169 |
| A | ALA173 |
| A | ILE174 |
| A | GLY175 |
| A | SER217 |
| A | LEU236 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | LYS12 |
| A | ALA173 |
| A | ILE174 |
| A | GLY175 |
| A | GLY216 |
| A | SER217 |
| A | GLY238 |
| A | GLY239 |
| A | 13P301 |
| A | HOH451 |
| A | HOH456 |
| A | HOH537 |
| A | HOH548 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | GLU50 |
| A | ASN51 |
| B | GLU50 |
| B | ASN51 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | ARG116 |
| A | ILE156 |
| A | PHE160 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | SER204 |
| A | GLU208 |
| A | HOH401 |
| B | ARG136 |
| B | GLN184 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | SER146 |
| A | SER147 |
| A | ARG150 |
| A | GLU151 |
| A | HOH463 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | LYS4 |
| A | SER162 |
| A | LEU164 |
| A | ILE210 |
| A | SER211 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 308 |
| Chain | Residue |
| A | PRO220 |
| A | ASP221 |
| A | ASN222 |
| A | ILE223 |
| A | GLN224 |
| A | ASP225 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 309 |
| Chain | Residue |
| A | LEU104 |
| A | HOH553 |
| B | GLY105 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 310 |
| Chain | Residue |
| A | GLU143 |
| A | PHE191 |
| A | HOH419 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 311 |
| Chain | Residue |
| B | LEU133 |
| B | TRP172 |
| B | GLN184 |
| site_id | AD3 |
| Number of Residues | 17 |
| Details | binding site for residue 13P B 301 |
| Chain | Residue |
| B | ASN10 |
| B | LYS12 |
| B | HIS97 |
| B | GLU169 |
| B | ALA173 |
| B | ILE174 |
| B | GLY175 |
| B | SER217 |
| B | LEU236 |
| B | GLY238 |
| B | GLY239 |
| B | SO4302 |
| B | HOH444 |
| B | HOH501 |
| B | HOH532 |
| B | HOH533 |
| B | HOH534 |
| site_id | AD4 |
| Number of Residues | 12 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| B | ALA173 |
| B | ILE174 |
| B | GLY175 |
| B | SER217 |
| B | GLY238 |
| B | GLY239 |
| B | 13P301 |
| B | HOH444 |
| B | HOH501 |
| B | HOH532 |
| B | HOH533 |
| B | HOH534 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | PHE160 |
| B | HOH450 |
| B | HOH524 |
| B | ARG116 |
| B | LYS120 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| A | ARG136 |
| A | GLN184 |
| B | GLY202 |
| B | EDO305 |
| B | HOH405 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 305 |
| Chain | Residue |
| A | TRP172 |
| A | LYS178 |
| A | GLN184 |
| B | EDO304 |
| B | HOH404 |
| site_id | AD8 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 306 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 307 |
| Chain | Residue |
| B | HIS70 |
| B | PHE117 |
| B | HOH539 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 308 |
| Chain | Residue |
| A | HOH431 |
| A | HOH553 |
| B | PHE103 |
Functional Information from PROSITE/UniProt
| site_id | PS00171 |
| Number of Residues | 11 |
| Details | TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG |
| Chain | Residue | Details |
| A | ALA167-GLY177 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Electrophile","evidences":[{"source":"HAMAP-Rule","id":"MF_00147","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00147","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00147","evidenceCode":"ECO:0000255"}]} |
