4YK7

Crystal structure of S-hydroxynitrile lyase from Manihot esculenta (His103Leu)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016829	molecular_function	lyase activity
A	0047606	molecular_function	(S)-hydroxynitrile lyase activity
A	0052891	molecular_function	aliphatic (S)-hydroxynitrile lyase activity
A	0052892	molecular_function	aromatic (S)-hydroxynitrile lyase activity
B	0003824	molecular_function	catalytic activity
B	0016829	molecular_function	lyase activity
B	0047606	molecular_function	(S)-hydroxynitrile lyase activity
B	0052891	molecular_function	aliphatic (S)-hydroxynitrile lyase activity
B	0052892	molecular_function	aromatic (S)-hydroxynitrile lyase activity
C	0003824	molecular_function	catalytic activity
C	0016829	molecular_function	lyase activity
C	0047606	molecular_function	(S)-hydroxynitrile lyase activity
C	0052891	molecular_function	aliphatic (S)-hydroxynitrile lyase activity
C	0052892	molecular_function	aromatic (S)-hydroxynitrile lyase activity
D	0003824	molecular_function	catalytic activity
D	0016829	molecular_function	lyase activity
D	0047606	molecular_function	(S)-hydroxynitrile lyase activity
D	0052891	molecular_function	aliphatic (S)-hydroxynitrile lyase activity
D	0052892	molecular_function	aromatic (S)-hydroxynitrile lyase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	948
Details	Domain: {"description":"AB hydrolase-1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"11173464","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"11316882","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11173464","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DWO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	4
Details	Site: {"description":"Increases basicity of active site His","evidences":[{"source":"PubMed","id":"11316882","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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