4YJK
Crystal structure of C212S mutant of Shewanella oneidensis MR-1 uridine phosphorylase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004850 | molecular_function | uridine phosphorylase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0009166 | biological_process | nucleotide catabolic process |
| A | 0016763 | molecular_function | pentosyltransferase activity |
| A | 0044206 | biological_process | UMP salvage |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004850 | molecular_function | uridine phosphorylase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0009116 | biological_process | nucleoside metabolic process |
| B | 0009166 | biological_process | nucleotide catabolic process |
| B | 0016763 | molecular_function | pentosyltransferase activity |
| B | 0044206 | biological_process | UMP salvage |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004850 | molecular_function | uridine phosphorylase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0009116 | biological_process | nucleoside metabolic process |
| C | 0009166 | biological_process | nucleotide catabolic process |
| C | 0016763 | molecular_function | pentosyltransferase activity |
| C | 0044206 | biological_process | UMP salvage |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004850 | molecular_function | uridine phosphorylase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0009116 | biological_process | nucleoside metabolic process |
| D | 0009166 | biological_process | nucleotide catabolic process |
| D | 0016763 | molecular_function | pentosyltransferase activity |
| D | 0044206 | biological_process | UMP salvage |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0004850 | molecular_function | uridine phosphorylase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0009116 | biological_process | nucleoside metabolic process |
| E | 0009166 | biological_process | nucleotide catabolic process |
| E | 0016763 | molecular_function | pentosyltransferase activity |
| E | 0044206 | biological_process | UMP salvage |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0004850 | molecular_function | uridine phosphorylase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0009116 | biological_process | nucleoside metabolic process |
| F | 0009166 | biological_process | nucleotide catabolic process |
| F | 0016763 | molecular_function | pentosyltransferase activity |
| F | 0044206 | biological_process | UMP salvage |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue URA D 301 |
| Chain | Residue |
| D | THR91 |
| D | HOH529 |
| D | THR92 |
| D | GLY93 |
| D | PHE159 |
| D | GLN163 |
| D | ARG165 |
| D | GLU193 |
| D | MET194 |
| D | HOH427 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 D 302 |
| Chain | Residue |
| C | ARG45 |
| D | GLY23 |
| D | ARG27 |
| D | ARG88 |
| D | VAL89 |
| D | GLY90 |
| D | THR91 |
| D | HOH517 |
| D | HOH529 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 D 303 |
| Chain | Residue |
| D | ARG30 |
| D | SER237 |
| D | ALA238 |
| D | VAL239 |
| D | HOH528 |
| D | HOH538 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 D 304 |
| Chain | Residue |
| B | ARG175 |
| D | ARG175 |
| D | HOH545 |
| D | HOH546 |
| D | HOH547 |
| D | HOH549 |
| F | ARG175 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | binding site for residue URA F 301 |
| Chain | Residue |
| F | THR92 |
| F | GLY93 |
| F | PHE159 |
| F | GLN163 |
| F | ARG165 |
| F | TYR192 |
| F | GLU193 |
| F | MET194 |
| F | VAL218 |
| F | HOH429 |
| F | HOH518 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 F 302 |
| Chain | Residue |
| E | ARG45 |
| F | GLY23 |
| F | ARG27 |
| F | ARG88 |
| F | VAL89 |
| F | GLY90 |
| F | THR91 |
| F | HOH508 |
| F | HOH518 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | binding site for residue URA A 301 |
| Chain | Residue |
| A | THR91 |
| A | THR92 |
| A | GLY93 |
| A | PHE159 |
| A | GLN163 |
| A | ARG165 |
| A | TYR192 |
| A | GLU193 |
| A | MET194 |
| A | HOH447 |
| A | HOH549 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | GLY23 |
| A | ARG27 |
| A | ARG88 |
| A | VAL89 |
| A | GLY90 |
| A | THR91 |
| B | ARG45 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 C 301 |
| Chain | Residue |
| C | GLY23 |
| C | ARG27 |
| C | ARG88 |
| C | VAL89 |
| C | GLY90 |
| C | THR91 |
| C | HOH531 |
| C | HOH533 |
| D | ARG45 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 E 301 |
| Chain | Residue |
| A | ARG175 |
| C | ARG175 |
| E | ARG175 |
| E | HOH419 |
| E | HOH420 |
| E | HOH421 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 E 302 |
| Chain | Residue |
| E | ARG27 |
| E | ARG88 |
| E | THR91 |
| E | HOH506 |
| E | HOH515 |
| F | ARG45 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 B 301 |
| Chain | Residue |
| B | HOH504 |
| A | ARG45 |
| B | GLY23 |
| B | ARG27 |
| B | ARG88 |
| B | VAL89 |
| B | GLY90 |
| B | THR91 |
| B | HOH497 |
Functional Information from PROSITE/UniProt
| site_id | PS01232 |
| Number of Residues | 16 |
| Details | PNP_UDP_1 Purine and other phosphorylases family 1 signature. StGIGgPStSIaveEL |
| Chain | Residue | Details |
| D | SER63-LEU78 |
