Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4YJK

Crystal structure of C212S mutant of Shewanella oneidensis MR-1 uridine phosphorylase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004850	molecular_function	uridine phosphorylase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0009116	biological_process	nucleoside metabolic process
A	0009164	biological_process	nucleoside catabolic process
A	0009166	biological_process	nucleotide catabolic process
A	0016757	molecular_function	glycosyltransferase activity
A	0016763	molecular_function	pentosyltransferase activity
A	0044206	biological_process	UMP salvage
A	0047847	molecular_function	deoxyuridine phosphorylase activity
B	0003824	molecular_function	catalytic activity
B	0004850	molecular_function	uridine phosphorylase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0009116	biological_process	nucleoside metabolic process
B	0009164	biological_process	nucleoside catabolic process
B	0009166	biological_process	nucleotide catabolic process
B	0016757	molecular_function	glycosyltransferase activity
B	0016763	molecular_function	pentosyltransferase activity
B	0044206	biological_process	UMP salvage
B	0047847	molecular_function	deoxyuridine phosphorylase activity
C	0003824	molecular_function	catalytic activity
C	0004850	molecular_function	uridine phosphorylase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0009116	biological_process	nucleoside metabolic process
C	0009164	biological_process	nucleoside catabolic process
C	0009166	biological_process	nucleotide catabolic process
C	0016757	molecular_function	glycosyltransferase activity
C	0016763	molecular_function	pentosyltransferase activity
C	0044206	biological_process	UMP salvage
C	0047847	molecular_function	deoxyuridine phosphorylase activity
D	0003824	molecular_function	catalytic activity
D	0004850	molecular_function	uridine phosphorylase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0009116	biological_process	nucleoside metabolic process
D	0009164	biological_process	nucleoside catabolic process
D	0009166	biological_process	nucleotide catabolic process
D	0016757	molecular_function	glycosyltransferase activity
D	0016763	molecular_function	pentosyltransferase activity
D	0044206	biological_process	UMP salvage
D	0047847	molecular_function	deoxyuridine phosphorylase activity
E	0003824	molecular_function	catalytic activity
E	0004850	molecular_function	uridine phosphorylase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0009116	biological_process	nucleoside metabolic process
E	0009164	biological_process	nucleoside catabolic process
E	0009166	biological_process	nucleotide catabolic process
E	0016757	molecular_function	glycosyltransferase activity
E	0016763	molecular_function	pentosyltransferase activity
E	0044206	biological_process	UMP salvage
E	0047847	molecular_function	deoxyuridine phosphorylase activity
F	0003824	molecular_function	catalytic activity
F	0004850	molecular_function	uridine phosphorylase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0009116	biological_process	nucleoside metabolic process
F	0009164	biological_process	nucleoside catabolic process
F	0009166	biological_process	nucleotide catabolic process
F	0016757	molecular_function	glycosyltransferase activity
F	0016763	molecular_function	pentosyltransferase activity
F	0044206	biological_process	UMP salvage
F	0047847	molecular_function	deoxyuridine phosphorylase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue URA D 301

Chain	Residue
D	THR91
D	HOH529
D	THR92
D	GLY93
D	PHE159
D	GLN163
D	ARG165
D	GLU193
D	MET194
D	HOH427

site_id	AC2
Number of Residues	9
Details	binding site for residue SO4 D 302

Chain	Residue
C	ARG45
D	GLY23
D	ARG27
D	ARG88
D	VAL89
D	GLY90
D	THR91
D	HOH517
D	HOH529

site_id	AC3
Number of Residues	6
Details	binding site for residue SO4 D 303

Chain	Residue
D	ARG30
D	SER237
D	ALA238
D	VAL239
D	HOH528
D	HOH538

site_id	AC4
Number of Residues	7
Details	binding site for residue SO4 D 304

Chain	Residue
B	ARG175
D	ARG175
D	HOH545
D	HOH546
D	HOH547
D	HOH549
F	ARG175

site_id	AC5
Number of Residues	11
Details	binding site for residue URA F 301

Chain	Residue
F	THR92
F	GLY93
F	PHE159
F	GLN163
F	ARG165
F	TYR192
F	GLU193
F	MET194
F	VAL218
F	HOH429
F	HOH518

site_id	AC6
Number of Residues	9
Details	binding site for residue SO4 F 302

Chain	Residue
E	ARG45
F	GLY23
F	ARG27
F	ARG88
F	VAL89
F	GLY90
F	THR91
F	HOH508
F	HOH518

site_id	AC7
Number of Residues	11
Details	binding site for residue URA A 301

Chain	Residue
A	THR91
A	THR92
A	GLY93
A	PHE159
A	GLN163
A	ARG165
A	TYR192
A	GLU193
A	MET194
A	HOH447
A	HOH549

site_id	AC8
Number of Residues	7
Details	binding site for residue SO4 A 302

Chain	Residue
A	GLY23
A	ARG27
A	ARG88
A	VAL89
A	GLY90
A	THR91
B	ARG45

site_id	AC9
Number of Residues	9
Details	binding site for residue SO4 C 301

Chain	Residue
C	GLY23
C	ARG27
C	ARG88
C	VAL89
C	GLY90
C	THR91
C	HOH531
C	HOH533
D	ARG45

site_id	AD1
Number of Residues	6
Details	binding site for residue SO4 E 301

Chain	Residue
A	ARG175
C	ARG175
E	ARG175
E	HOH419
E	HOH420
E	HOH421

site_id	AD2
Number of Residues	6
Details	binding site for residue SO4 E 302

Chain	Residue
E	ARG27
E	ARG88
E	THR91
E	HOH506
E	HOH515
F	ARG45

site_id	AD3
Number of Residues	9
Details	binding site for residue SO4 B 301

Chain	Residue
B	HOH504
A	ARG45
B	GLY23
B	ARG27
B	ARG88
B	VAL89
B	GLY90
B	THR91
B	HOH497

Functional Information from PROSITE/UniProt

site_id	PS01232
Number of Residues	16
Details	PNP_UDP_1 Purine and other phosphorylases family 1 signature. StGIGgPStSIaveEL

Chain	Residue	Details
D	SER63-LEU78

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)