4YI9
Crystal structure of non-myristoylated E153A recoverin at 1.35 A resolution with a sodium ion bound to EF-hand 2 and calcium ion bound to EF-hand 3
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001750 | cellular_component | photoreceptor outer segment |
| A | 0001917 | cellular_component | photoreceptor inner segment |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0007601 | biological_process | visual perception |
| A | 0007602 | biological_process | phototransduction |
| A | 0009966 | biological_process | regulation of signal transduction |
| A | 0043204 | cellular_component | perikaryon |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051924 | biological_process | regulation of calcium ion transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 301 |
| Chain | Residue |
| A | ASP74 |
| A | ASN76 |
| A | ASP78 |
| A | THR80 |
| A | HOH433 |
| A | HOH460 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 302 |
| Chain | Residue |
| A | THR116 |
| A | GLU121 |
| A | HOH509 |
| A | ASP110 |
| A | ASP112 |
| A | ASN114 |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DANSDGTLDfkEY |
| Chain | Residue | Details |
| A | ASP74-TYR86 | |
| A | ASP110-VAL122 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 35 |
| Details | Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 35 |
| Details | Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 35 |
| Details | Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 35 |
| Details | Domain: {"description":"EF-hand 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Region: {"description":"Interaction with GRK1","evidences":[{"source":"PubMed","id":"21299498","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11980481","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YI8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11980481","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12686556","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17015448","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17020884","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24189072","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26584024","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7630423","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8242744","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OMR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OMV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1REC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I94","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI9","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11980481","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12686556","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17015448","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17020884","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24189072","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26584024","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7630423","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8242744","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OMV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1REC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I94","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI9","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11980481","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12686556","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17020884","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24189072","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26584024","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7630423","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8242744","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OMR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OMV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1REC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I94","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI9","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11980481","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12686556","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17015448","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17020884","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24189072","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26584024","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7630423","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8242744","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OMR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OMV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1REC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I94","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI9","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11980481","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12686556","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17015448","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17020884","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24189072","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26584024","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7630423","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OMR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OMV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I94","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4M2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4YI8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with GRK1","evidences":[{"source":"PubMed","id":"21299498","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Cysteine sulfenic acid (-SOH)","evidences":[{"source":"PubMed","id":"24189072","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25772009","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
