4YH1

Structure of Human Scp1 bound to cis-proline peptidomimetic CTD phospho-Ser5 peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016791	molecular_function	phosphatase activity
B	0016791	molecular_function	phosphatase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MG A 301

Chain	Residue
A	ASN96
A	ASP98
A	ASN207
A	HOH426
A	HOH450
C	HOH104

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site_id	AC2
Number of Residues	5
Details	binding site for residue MG B 301

Chain	Residue
B	HOH458
B	HOH466
B	ASN96
B	ASP98
B	ASN207

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: 4-aspartylphosphate intermediate => ECO:0000269|PubMed:15304220, ECO:0000269|PubMed:17157258

Chain	Residue	Details
A	LEU97
B	LEU97

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Proton donor => ECO:0000305|PubMed:15304220

Chain	Residue	Details
A	GLU99
B	GLU99

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site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:15304220

Chain	Residue	Details
B	GLU99
B	SER208
A	LEU97
A	GLU99
A	SER208
B	LEU97

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site_id	SWS_FT_FI4
Number of Residues	4
Details	SITE: Transition state stabilizer => ECO:0000305|PubMed:15304220

Chain	Residue	Details
B	ALA153
B	ASP191
A	ALA153
A	ASP191

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