Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 1401 |
| Chain | Residue |
| A | THR1269 |
| A | GLN1273 |
| A | MET1291 |
| A | ALA1292 |
| A | ALA1293 |
| A | LYS1342 |
| A | HOH1674 |
| A | HOH1746 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 1402 |
| Chain | Residue |
| A | THR1184 |
| A | TRP1185 |
| A | GLN1298 |
| A | HOH1690 |
| A | HOH1744 |
| B | GLU1356 |
| B | EDO1403 |
| A | ARG1183 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue EDO A 1403 |
| Chain | Residue |
| A | PHE1212 |
| A | PRO1215 |
| A | ILE1217 |
| A | SER1355 |
| A | GLU1356 |
| A | EDO1409 |
| A | HOH1591 |
| A | HOH1695 |
| B | ARG1183 |
| B | HOH1621 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1404 |
| Chain | Residue |
| A | LYS1252 |
| A | LYS1254 |
| A | ARG1301 |
| A | GLU1360 |
| A | HOH1578 |
| A | HOH1739 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 1405 |
| Chain | Residue |
| A | GLU1200 |
| A | ALA1201 |
| A | LEU1202 |
| A | ILE1286 |
| A | TYR1314 |
| A | TYR1338 |
| A | HOH1665 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 1406 |
| Chain | Residue |
| A | TRP1185 |
| A | LYS1254 |
| A | LEU1299 |
| A | THR1300 |
| A | ARG1301 |
| A | EDO1408 |
| A | HOH1515 |
| A | HOH1535 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 1407 |
| Chain | Residue |
| A | LEU1299 |
| A | ARG1301 |
| A | EDO1408 |
| A | EDO1410 |
| A | HOH1533 |
| A | HOH1534 |
| B | EDO1404 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 1408 |
| Chain | Residue |
| A | TRP1185 |
| A | LEU1299 |
| A | SER1358 |
| A | EDO1406 |
| A | EDO1407 |
| A | EDO1410 |
| A | HOH1587 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 1409 |
| Chain | Residue |
| A | SER1355 |
| A | GLU1356 |
| A | ILE1357 |
| A | EDO1403 |
| A | EDO1410 |
| A | EDO1411 |
| A | HOH1591 |
| A | HOH1695 |
| B | ARG1183 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 1410 |
| Chain | Residue |
| A | GLU1356 |
| A | EDO1407 |
| A | EDO1408 |
| A | EDO1409 |
| A | HOH1534 |
| A | HOH1535 |
| B | EDO1404 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 1411 |
| Chain | Residue |
| A | THR1187 |
| A | LEU1188 |
| A | ILE1357 |
| A | EDO1409 |
| B | THR1184 |
| site_id | AD3 |
| Number of Residues | 11 |
| Details | binding site for residue EDO B 1401 |
| Chain | Residue |
| A | ARG1183 |
| B | GLN1192 |
| B | PRO1215 |
| B | ILE1217 |
| B | SER1355 |
| B | GLU1356 |
| B | HOH1614 |
| B | HOH1615 |
| B | HOH1706 |
| B | HOH1718 |
| B | HOH1719 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 1402 |
| Chain | Residue |
| B | HOH1534 |
| B | GLN1203 |
| B | HIS1204 |
| B | THR1205 |
| B | ALA1292 |
| B | ALA1293 |
| B | HOH1530 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 1403 |
| Chain | Residue |
| A | THR1184 |
| A | GLN1298 |
| A | EDO1402 |
| A | HOH1690 |
| A | HOH1696 |
| B | TRP1185 |
| B | THR1187 |
| B | HOH1545 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 1404 |
| Chain | Residue |
| A | EDO1407 |
| A | EDO1410 |
| B | ILE1182 |
| B | ARG1183 |
| B | TRP1185 |
