4YAR

2-Hydroxyethylphosphonate dioxygenase (HEPD) E176H

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0008198	molecular_function	ferrous iron binding
A	0016491	molecular_function	oxidoreductase activity
A	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
A	0017000	biological_process	antibiotic biosynthetic process
A	0032923	biological_process	organic phosphonate biosynthetic process
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0046872	molecular_function	metal ion binding
A	0051213	molecular_function	dioxygenase activity
A	0055114	biological_process	obsolete oxidation-reduction process
A	1901766	biological_process	phosphinothricin biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue CD A 501

Chain	Residue
A	HIS129
A	HIS176
A	HIS182
A	HOH695
A	HOH696
A	HOH697
A	HOH728

---

site_id	AC2
Number of Residues	2
Details	binding site for residue CD A 502

Chain	Residue
A	ASP66
A	ARG107

---

site_id	AC3
Number of Residues	1
Details	binding site for residue CD A 503

Chain	Residue
A	HIS75

---

site_id	AC4
Number of Residues	5
Details	binding site for residue CD A 504

Chain	Residue
A	HIS10
A	GLU131
A	ACT512
A	HOH604
A	HOH638

---

site_id	AC5
Number of Residues	6
Details	binding site for residue CD A 505

Chain	Residue
A	ASP32
A	ASP309
A	HOH601
A	HOH611
A	HOH624
A	HOH641

---

site_id	AC6
Number of Residues	4
Details	binding site for residue CD A 506

Chain	Residue
A	HIS94
A	HOH670
A	HOH705
A	HOH711

---

site_id	AC7
Number of Residues	5
Details	binding site for residue CD A 507

Chain	Residue
A	ASP142
A	HIS160
A	HIS163
A	ACT513
A	HOH803

---

site_id	AC8
Number of Residues	2
Details	binding site for residue CD A 508

Chain	Residue
A	ASP189
A	CD510

---

site_id	AC9
Number of Residues	2
Details	binding site for residue CD A 509

Chain	Residue
A	GLU80
A	HOH802

---

site_id	AD1
Number of Residues	4
Details	binding site for residue CD A 510

Chain	Residue
A	ASP189
A	GLU368
A	HIS397
A	CD508

---

site_id	AD2
Number of Residues	6
Details	binding site for residue NA A 511

Chain	Residue
A	GLN296
A	HIS330
A	HOH605
A	HOH702
A	HOH783
A	HOH806

---

site_id	AD3
Number of Residues	7
Details	binding site for residue ACT A 512

Chain	Residue
A	HIS10
A	ASN13
A	LEU130
A	GLU131
A	TYR179
A	CD504
A	HOH604

---

site_id	AD4
Number of Residues	6
Details	binding site for residue ACT A 513

Chain	Residue
A	ASP142
A	HIS160
A	HIS163
A	ASP373
A	CD507
A	HOH803

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	55
Details	Domain: {"description":"HTH cro/C1-type 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	56
Details	Domain: {"description":"HTH cro/C1-type 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	39
Details	DNA binding: {"description":"H-T-H motif","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PDB","id":"3GBF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	5
Details	Binding site: {"description":"in other chain","evidences":[{"source":"PDB","id":"3GBF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19516340","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21711001","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3G7D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GBF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RZZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---