4Y4L
Crystal structure of yeast Thi4-C205S
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008198 | molecular_function | ferrous iron binding |
| A | 0009228 | biological_process | thiamine biosynthetic process |
| A | 0016763 | molecular_function | pentosyltransferase activity |
| A | 0052837 | biological_process | thiazole biosynthetic process |
| A | 0160205 | molecular_function | cysteine-dependent adenosine diphosphate thiazole synthase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008198 | molecular_function | ferrous iron binding |
| B | 0009228 | biological_process | thiamine biosynthetic process |
| B | 0016763 | molecular_function | pentosyltransferase activity |
| B | 0052837 | biological_process | thiazole biosynthetic process |
| B | 0160205 | molecular_function | cysteine-dependent adenosine diphosphate thiazole synthase activity |
| C | 0005506 | molecular_function | iron ion binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0008198 | molecular_function | ferrous iron binding |
| C | 0009228 | biological_process | thiamine biosynthetic process |
| C | 0016763 | molecular_function | pentosyltransferase activity |
| C | 0052837 | biological_process | thiazole biosynthetic process |
| C | 0160205 | molecular_function | cysteine-dependent adenosine diphosphate thiazole synthase activity |
| D | 0005506 | molecular_function | iron ion binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0008198 | molecular_function | ferrous iron binding |
| D | 0009228 | biological_process | thiamine biosynthetic process |
| D | 0016763 | molecular_function | pentosyltransferase activity |
| D | 0052837 | biological_process | thiazole biosynthetic process |
| D | 0160205 | molecular_function | cysteine-dependent adenosine diphosphate thiazole synthase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 32 |
| Details | binding site for residue 48N A 401 |
| Chain | Residue |
| A | GLY72 |
| A | GLY105 |
| A | CYS169 |
| A | VAL170 |
| A | ASP207 |
| A | PRO208 |
| A | THR234 |
| A | THR235 |
| A | GLY236 |
| A | HIS237 |
| A | PHE241 |
| A | GLY74 |
| A | GLY290 |
| A | MET291 |
| A | ARG301 |
| A | MET302 |
| A | GLY303 |
| A | THR305 |
| A | PHE306 |
| A | MET309 |
| A | HOH503 |
| A | HOH522 |
| A | SER75 |
| A | HOH527 |
| A | HOH530 |
| A | HOH532 |
| A | SER76 |
| A | ILE96 |
| A | GLU97 |
| A | SER98 |
| A | SER99 |
| A | GLY104 |
| site_id | AC2 |
| Number of Residues | 35 |
| Details | binding site for residue 48N B 401 |
| Chain | Residue |
| B | VAL71 |
| B | GLY72 |
| B | GLY74 |
| B | SER75 |
| B | SER76 |
| B | ILE96 |
| B | GLU97 |
| B | SER98 |
| B | SER99 |
| B | GLY104 |
| B | GLY105 |
| B | CYS169 |
| B | VAL170 |
| B | ASP207 |
| B | PRO208 |
| B | THR234 |
| B | THR235 |
| B | GLY236 |
| B | HIS237 |
| B | PHE241 |
| B | GLY290 |
| B | MET291 |
| B | ARG301 |
| B | MET302 |
| B | GLY303 |
| B | THR305 |
| B | PHE306 |
| B | MET309 |
| B | HOH502 |
| B | HOH509 |
| B | HOH524 |
| B | HOH525 |
| B | HOH532 |
| B | HOH541 |
| B | HOH573 |
| site_id | AC3 |
| Number of Residues | 33 |
| Details | binding site for residue 48N C 401 |
| Chain | Residue |
| C | HOH551 |
| C | GLY72 |
| C | GLY74 |
| C | SER75 |
| C | SER76 |
| C | ILE96 |
| C | GLU97 |
| C | SER98 |
| C | SER99 |
| C | GLY104 |
| C | GLY105 |
| C | CYS169 |
| C | VAL170 |
| C | ASP207 |
| C | PRO208 |
| C | THR234 |
| C | THR235 |
| C | GLY236 |
| C | HIS237 |
| C | PHE241 |
| C | PHE244 |
| C | GLY290 |
| C | MET291 |
| C | ARG301 |
| C | MET302 |
| C | GLY303 |
| C | THR305 |
| C | PHE306 |
| C | MET309 |
| C | HOH501 |
| C | HOH519 |
| C | HOH522 |
| C | HOH532 |
| site_id | AC4 |
| Number of Residues | 32 |
| Details | binding site for residue 48N D 401 |
| Chain | Residue |
| D | GLY72 |
| D | GLY74 |
| D | SER75 |
| D | SER76 |
| D | ILE96 |
| D | GLU97 |
| D | SER98 |
| D | SER99 |
| D | GLY104 |
| D | GLY105 |
| D | CYS169 |
| D | VAL170 |
| D | ASP207 |
| D | PRO208 |
| D | THR234 |
| D | THR235 |
| D | GLY236 |
| D | HIS237 |
| D | PHE241 |
| D | GLY290 |
| D | MET291 |
| D | ARG301 |
| D | MET302 |
| D | GLY303 |
| D | THR305 |
| D | PHE306 |
| D | MET309 |
| D | HOH501 |
| D | HOH525 |
| D | HOH527 |
| D | HOH539 |
| D | HOH567 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"2,3-didehydroalanine (Cys)","evidences":[{"source":"PubMed","id":"22031445","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
