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4Y4L

Crystal structure of yeast Thi4-C205S

Functional Information from GO Data
ChainGOidnamespacecontents
A0000002biological_processmitochondrial genome maintenance
A0005506molecular_functioniron ion binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0008198molecular_functionferrous iron binding
A0009228biological_processthiamine biosynthetic process
A0016740molecular_functiontransferase activity
A0016763molecular_functionpentosyltransferase activity
A0046872molecular_functionmetal ion binding
A0052837biological_processthiazole biosynthetic process
B0000002biological_processmitochondrial genome maintenance
B0005506molecular_functioniron ion binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0008198molecular_functionferrous iron binding
B0009228biological_processthiamine biosynthetic process
B0016740molecular_functiontransferase activity
B0016763molecular_functionpentosyltransferase activity
B0046872molecular_functionmetal ion binding
B0052837biological_processthiazole biosynthetic process
C0000002biological_processmitochondrial genome maintenance
C0005506molecular_functioniron ion binding
C0005634cellular_componentnucleus
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0008198molecular_functionferrous iron binding
C0009228biological_processthiamine biosynthetic process
C0016740molecular_functiontransferase activity
C0016763molecular_functionpentosyltransferase activity
C0046872molecular_functionmetal ion binding
C0052837biological_processthiazole biosynthetic process
D0000002biological_processmitochondrial genome maintenance
D0005506molecular_functioniron ion binding
D0005634cellular_componentnucleus
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0008198molecular_functionferrous iron binding
D0009228biological_processthiamine biosynthetic process
D0016740molecular_functiontransferase activity
D0016763molecular_functionpentosyltransferase activity
D0046872molecular_functionmetal ion binding
D0052837biological_processthiazole biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues32
Detailsbinding site for residue 48N A 401
ChainResidue
AGLY72
AGLY105
ACYS169
AVAL170
AASP207
APRO208
ATHR234
ATHR235
AGLY236
AHIS237
APHE241
AGLY74
AGLY290
AMET291
AARG301
AMET302
AGLY303
ATHR305
APHE306
AMET309
AHOH503
AHOH522
ASER75
AHOH527
AHOH530
AHOH532
ASER76
AILE96
AGLU97
ASER98
ASER99
AGLY104

site_idAC2
Number of Residues35
Detailsbinding site for residue 48N B 401
ChainResidue
BVAL71
BGLY72
BGLY74
BSER75
BSER76
BILE96
BGLU97
BSER98
BSER99
BGLY104
BGLY105
BCYS169
BVAL170
BASP207
BPRO208
BTHR234
BTHR235
BGLY236
BHIS237
BPHE241
BGLY290
BMET291
BARG301
BMET302
BGLY303
BTHR305
BPHE306
BMET309
BHOH502
BHOH509
BHOH524
BHOH525
BHOH532
BHOH541
BHOH573

site_idAC3
Number of Residues33
Detailsbinding site for residue 48N C 401
ChainResidue
CHOH551
CGLY72
CGLY74
CSER75
CSER76
CILE96
CGLU97
CSER98
CSER99
CGLY104
CGLY105
CCYS169
CVAL170
CASP207
CPRO208
CTHR234
CTHR235
CGLY236
CHIS237
CPHE241
CPHE244
CGLY290
CMET291
CARG301
CMET302
CGLY303
CTHR305
CPHE306
CMET309
CHOH501
CHOH519
CHOH522
CHOH532

site_idAC4
Number of Residues32
Detailsbinding site for residue 48N D 401
ChainResidue
DGLY72
DGLY74
DSER75
DSER76
DILE96
DGLU97
DSER98
DSER99
DGLY104
DGLY105
DCYS169
DVAL170
DASP207
DPRO208
DTHR234
DTHR235
DGLY236
DHIS237
DPHE241
DGLY290
DMET291
DARG301
DMET302
DGLY303
DTHR305
DPHE306
DMET309
DHOH501
DHOH525
DHOH527
DHOH539
DHOH567

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues32
DetailsBINDING:
ChainResidueDetails
BASP207
BHIS237
BMET291
BARG301
CSER76
CGLU97
CGLY105
CVAL170
CASP207
CHIS237
CMET291
CARG301
DSER76
DGLU97
DGLY105
DVAL170
DASP207
DHIS237
DMET291
DARG301
AVAL170
AASP207
AHIS237
AMET291
AARG301
BSER76
BGLU97
BGLY105
BVAL170
ASER76
AGLU97
AGLY105

site_idSWS_FT_FI2
Number of Residues4
DetailsMOD_RES: 2,3-didehydroalanine (Cys) => ECO:0000269|PubMed:22031445
ChainResidueDetails
ASER205
BSER205
CSER205
DSER205

221051

PDB entries from 2024-06-12

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