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4Y3W

Endothiapepsin in complex with fragment 35

Functional Information from GO Data
ChainGOidnamespacecontents
A0004190molecular_functionaspartic-type endopeptidase activity
A0006508biological_processproteolysis
Functional Information from PDB Data
site_idAC1
Number of Residues7
Detailsbinding site for residue GOL A 401
ChainResidue
AVAL272
APRO274
ATYR277
AALA312
ASER329
ALYS330
AHOH1340

site_idAC2
Number of Residues6
Detailsbinding site for residue 46Q A 402
ChainResidue
ASER115
APHE116
AGLU118
AASP119
AALA16
AASP81

site_idAC3
Number of Residues5
Detailsbinding site for residue 46Q A 403
ChainResidue
AASP15
APHE280
APRO282
AILE283
APHE291

site_idAC4
Number of Residues3
Detailsbinding site for residue EDO A 404
ChainResidue
AALA187
ATRP197
ATHR198

Functional Information from PROSITE/UniProt
site_idPS00141
Number of Residues12
DetailsASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV
ChainResidueDetails
ALEU32-VAL43
AGLY216-LEU227

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE:
ChainResidueDetails
AASP35
ASER199

226707

PDB entries from 2024-10-30

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