Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | ALA203 |
| A | VAL204 |
| A | GLY207 |
| A | THR208 |
| A | LYS210 |
| A | GOL404 |
| A | HOH2355 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | GLY301 |
| A | ILE302 |
| A | HOH867 |
| A | HOH948 |
| A | HOH1038 |
| A | HOH1071 |
| A | SER297 |
| A | ALA298 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | THR6 |
| A | PRO166 |
| A | GLY167 |
| A | THR168 |
| A | HOH1450 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | TYR202 |
| A | LYS210 |
| A | ALA234 |
| A | GOL401 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | GLN22 |
| A | GLY24 |
| A | THR25 |
| A | THR93 |
| A | VAL94 |
| A | SER95 |
| A | HOH1706 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue ACT A 406 |
| Chain | Residue |
| A | ILE183 |
| A | THR184 |
| A | TYR185 |
| A | SER287 |
| A | SER289 |
| A | HOH2331 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 407 |
| Chain | Residue |
| A | CYS255 |
| A | ASP279 |
| A | GLY281 |
| A | CYS290 |
| A | HOH2095 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 408 |
| Chain | Residue |
| A | VAL156 |
| A | SER284 |
| A | THR285 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 409 |
| Chain | Residue |
| A | ASP160 |
| A | GLY162 |
| A | PRO166 |
| A | GLY167 |
| A | LYS330 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 410 |
| Chain | Residue |
| A | PHE253 |
| A | PRO254 |
| A | SER289 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 411 |
| Chain | Residue |
| A | ALA187 |
| A | SER189 |
| A | THR198 |
| A | ASP215 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 412 |
| Chain | Residue |
| A | ASP81 |
| A | GLY82 |
| A | SER83 |
| A | SER113 |
| A | SER114 |
| A | SER115 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 413 |
| Chain | Residue |
| A | SER233 |
| A | ALA237 |
| A | TYR251 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 414 |
| Chain | Residue |
| A | GLY37 |
| A | SER78 |
| A | HOH678 |
| site_id | AD6 |
| Number of Residues | 10 |
| Details | binding site for residue HIC A 415 |
| Chain | Residue |
| A | ASP35 |
| A | TYR79 |
| A | ASP81 |
| A | PHE116 |
| A | LEU125 |
| A | GLY221 |
| A | THR222 |
| A | THR223 |
| A | HOH501 |
| A | HOH629 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
| Chain | Residue | Details |
| A | LEU32-VAL43 | |
| A | GLY216-LEU227 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | ASP35 | |
| A | SER199 | |
