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4Y36

Endothiapepsin in complex with fragment 4

Functional Information from GO Data
ChainGOidnamespacecontents
A0004190molecular_functionaspartic-type endopeptidase activity
A0006508biological_processproteolysis
Functional Information from PDB Data
site_idAC1
Number of Residues6
Detailsbinding site for residue GOL A 401
ChainResidue
AVAL272
ATYR277
AALA312
ASER329
ALYS330
AHOH1340

site_idAC2
Number of Residues5
Detailsbinding site for residue EDO A 402
ChainResidue
AASP215
AHOH974
AALA187
ATRP197
ATHR198

site_idAC3
Number of Residues4
Detailsbinding site for residue EDO A 403
ChainResidue
AGLY221
ATHR222
ATHR223
AHOH629

site_idAC4
Number of Residues2
Detailsbinding site for residue EDO A 404
ChainResidue
APRO26
AALA27

site_idAC5
Number of Residues3
Detailsbinding site for residue PGE A 405
ChainResidue
AASP15
APHE280
AHOH744

site_idAC6
Number of Residues7
Detailsbinding site for residue 45L A 406
ChainResidue
AASP35
AGLY37
ATYR79
AGLY80
AILE217
AASP219
AILE302

Functional Information from PROSITE/UniProt
site_idPS00141
Number of Residues12
DetailsASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV
ChainResidueDetails
ALEU32-VAL43
AGLY216-LEU227

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE:
ChainResidueDetails
AASP35
ASER199

226707

PDB entries from 2024-10-30

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