4Y2W
Crystal structure of a thermostable alanine racemase from Thermoanaerobacter tengcongensis MB4
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006522 | biological_process | alanine metabolic process |
| A | 0008784 | molecular_function | alanine racemase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0030632 | biological_process | D-alanine biosynthetic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006522 | biological_process | alanine metabolic process |
| B | 0008784 | molecular_function | alanine racemase activity |
| B | 0009252 | biological_process | peptidoglycan biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0030632 | biological_process | D-alanine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 A 401 |
| Chain | Residue |
| A | TYR44 |
| A | ASN208 |
| A | ALA209 |
| A | ARG224 |
| A | GLY226 |
| A | ILE227 |
| B | ALA402 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue ALA A 402 |
| Chain | Residue |
| A | CYS315 |
| A | MET316 |
| B | ARG138 |
| B | PO4401 |
| A | TYR268 |
| A | TYR287 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 B 401 |
| Chain | Residue |
| A | ALA402 |
| B | TYR44 |
| B | ASN208 |
| B | ALA209 |
| B | ARG224 |
| B | GLY226 |
| B | ILE227 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue ALA B 402 |
| Chain | Residue |
| A | GLN360 |
| A | PO4401 |
| B | TYR268 |
| B | TYR287 |
| B | MET316 |
Functional Information from PROSITE/UniProt
| site_id | PS00395 |
| Number of Residues | 11 |
| Details | ALANINE_RACEMASE Alanine racemase pyridoxal-phosphate attachment site. AViKGDAYGHG |
| Chain | Residue | Details |
| A | ALA37-GLY47 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor; specific for D-alanine","evidences":[{"source":"HAMAP-Rule","id":"MF_01201","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor; specific for L-alanine","evidences":[{"source":"HAMAP-Rule","id":"MF_01201","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01201","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"HAMAP-Rule","id":"MF_01201","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
