4Y2E
Crystal structure of the catalytic domain of human dual-specificity phosphatase 7 (C232S)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| A | 0017017 | molecular_function | MAP kinase tyrosine/serine/threonine phosphatase activity |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
| B | 0017017 | molecular_function | MAP kinase tyrosine/serine/threonine phosphatase activity |
| C | 0006470 | biological_process | protein dephosphorylation |
| C | 0016311 | biological_process | dephosphorylation |
| C | 0017017 | molecular_function | MAP kinase tyrosine/serine/threonine phosphatase activity |
| D | 0006470 | biological_process | protein dephosphorylation |
| D | 0016311 | biological_process | dephosphorylation |
| D | 0017017 | molecular_function | MAP kinase tyrosine/serine/threonine phosphatase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 A 301 |
| Chain | Residue |
| A | ASP201 |
| A | SER232 |
| A | LEU233 |
| A | ALA234 |
| A | GLY235 |
| A | ILE236 |
| A | SER237 |
| A | ARG238 |
| A | HOH469 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue PO4 B 301 |
| Chain | Residue |
| B | ASP201 |
| B | SER232 |
| B | LEU233 |
| B | ALA234 |
| B | GLY235 |
| B | ILE236 |
| B | SER237 |
| B | ARG238 |
| B | HOH468 |
| B | HOH570 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 C 301 |
| Chain | Residue |
| C | ASP201 |
| C | SER232 |
| C | LEU233 |
| C | ALA234 |
| C | GLY235 |
| C | ILE236 |
| C | SER237 |
| C | ARG238 |
| C | HOH469 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 D 301 |
| Chain | Residue |
| D | ASP201 |
| D | SER232 |
| D | LEU233 |
| D | ALA234 |
| D | GLY235 |
| D | ILE236 |
| D | SER237 |
| D | ARG238 |
| D | HOH468 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160 |
| Chain | Residue | Details |
| A | SER232 | |
| B | SER232 | |
| C | SER232 | |
| D | SER232 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26057789, ECO:0007744|PDB:4Y2E |
| Chain | Residue | Details |
| A | SER232 | |
| B | SER232 | |
| C | SER232 | |
| D | SER232 |
