4Y18
Structure of BRCA1 BRCT domains in complex with Abraxas double phosphorylated peptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006281 | biological_process | DNA repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008270 | molecular_function | zinc ion binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006281 | biological_process | DNA repair |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008270 | molecular_function | zinc ion binding |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| C | 0005634 | cellular_component | nucleus |
| C | 0006281 | biological_process | DNA repair |
| C | 0006974 | biological_process | DNA damage response |
| C | 0008270 | molecular_function | zinc ion binding |
| D | 0003677 | molecular_function | DNA binding |
| D | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| D | 0005634 | cellular_component | nucleus |
| D | 0006281 | biological_process | DNA repair |
| D | 0006974 | biological_process | DNA damage response |
| D | 0008270 | molecular_function | zinc ion binding |
| E | 0003677 | molecular_function | DNA binding |
| E | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| E | 0005634 | cellular_component | nucleus |
| E | 0006281 | biological_process | DNA repair |
| E | 0006974 | biological_process | DNA damage response |
| E | 0008270 | molecular_function | zinc ion binding |
| F | 0003677 | molecular_function | DNA binding |
| F | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| F | 0005634 | cellular_component | nucleus |
| F | 0006281 | biological_process | DNA repair |
| F | 0006974 | biological_process | DNA damage response |
| F | 0008270 | molecular_function | zinc ion binding |
| G | 0003677 | molecular_function | DNA binding |
| G | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| G | 0005634 | cellular_component | nucleus |
| G | 0006281 | biological_process | DNA repair |
| G | 0006974 | biological_process | DNA damage response |
| G | 0008270 | molecular_function | zinc ion binding |
| H | 0003677 | molecular_function | DNA binding |
| H | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| H | 0005634 | cellular_component | nucleus |
| H | 0006281 | biological_process | DNA repair |
| H | 0006974 | biological_process | DNA damage response |
| H | 0008270 | molecular_function | zinc ion binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 792 |
| Details | Domain: {"description":"BRCT 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00033","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"26778126","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17525340","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17643121","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17643122","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26778126","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
