Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004129 | molecular_function | cytochrome-c oxidase activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0009060 | biological_process | aerobic respiration |
| A | 0015990 | biological_process | electron transport coupled proton transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016966 | molecular_function | nitric oxide reductase activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0022904 | biological_process | respiratory electron transport chain |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0009055 | molecular_function | electron transfer activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016966 | molecular_function | nitric oxide reductase activity |
| B | 0020037 | molecular_function | heme binding |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue HEM A 501 |
| Chain | Residue |
| A | GLN23 |
| A | GLU122 |
| A | HIS336 |
| A | PHE339 |
| A | VAL344 |
| A | MET380 |
| A | ARG419 |
| A | VAL427 |
| A | CA503 |
| A | HEM504 |
| B | ALA73 |
| A | VAL24 |
| B | TYR74 |
| A | GLY27 |
| A | LEU28 |
| A | LEU30 |
| A | TYR34 |
| A | ARG50 |
| A | HIS53 |
| A | LEU57 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 503 |
| Chain | Residue |
| A | GLU122 |
| A | HEM501 |
| A | HEM504 |
| B | GLY72 |
| B | TYR74 |
| site_id | AC3 |
| Number of Residues | 25 |
| Details | binding site for residue HEM A 504 |
| Chain | Residue |
| A | GLU122 |
| A | PHE123 |
| A | TRP190 |
| A | VAL197 |
| A | GLU198 |
| A | HIS245 |
| A | HIS246 |
| A | GLU267 |
| A | PHE271 |
| A | ALA309 |
| A | GLY313 |
| A | PHE314 |
| A | HIS316 |
| A | THR317 |
| A | ASN322 |
| A | HIS326 |
| A | GLY327 |
| A | THR331 |
| A | HIS334 |
| A | ALA338 |
| A | PHE339 |
| A | TYR343 |
| A | HEM501 |
| A | CA503 |
| A | HOH609 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue FE A 505 |
| Chain | Residue |
| A | HIS194 |
| A | GLU198 |
| A | HIS245 |
| A | HIS246 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | binding site for residue HEC B 201 |
| Chain | Residue |
| A | ASN47 |
| A | MET406 |
| B | GLY61 |
| B | CYS62 |
| B | CYS65 |
| B | HIS66 |
| B | ALA76 |
| B | PRO77 |
| B | LEU79 |
| B | ARG85 |
| B | TRP86 |
| B | LEU99 |
| B | TRP102 |
| B | ARG113 |
| B | ARG114 |
| B | GLN115 |
| B | MET116 |
| B | PRO117 |
| B | HOH303 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue CU B 202 |
| Chain | Residue |
| B | GLU49 |
| B | HIS52 |
| B | GLU124 |
| B | HOH304 |
Functional Information from PROSITE/UniProt
| site_id | PS00077 |
| Number of Residues | 57 |
| Details | COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WYVVHLwVegtwelvmasvlaflmlkltgvdreiiekwlylivatalfsgilgtgHH |
| Chain | Residue | Details |
| A | TRP190-HIS246 | |
