Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0006584 | biological_process | catecholamine metabolic process |
| A | 0008171 | molecular_function | O-methyltransferase activity |
| A | 0016206 | molecular_function | catechol O-methyltransferase activity |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0006584 | biological_process | catecholamine metabolic process |
| B | 0008171 | molecular_function | O-methyltransferase activity |
| B | 0016206 | molecular_function | catechol O-methyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue 43J B 301 |
| Chain | Residue |
| A | LEU64 |
| B | GLU249 |
| B | MG302 |
| B | SAM303 |
| B | HOH420 |
| A | PRO69 |
| B | MET90 |
| B | ASP191 |
| B | HIS192 |
| B | TRP193 |
| B | LYS194 |
| B | ASP219 |
| B | ASN220 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 302 |
| Chain | Residue |
| B | ASP191 |
| B | ASP219 |
| B | ASN220 |
| B | 43J301 |
| B | HOH420 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | binding site for residue SAM B 303 |
| Chain | Residue |
| B | MET90 |
| B | ASN91 |
| B | VAL92 |
| B | GLY116 |
| B | ALA117 |
| B | TYR118 |
| B | TYR121 |
| B | SER122 |
| B | ILE139 |
| B | GLU140 |
| B | ILE141 |
| B | GLY167 |
| B | ALA168 |
| B | SER169 |
| B | GLN170 |
| B | ASP191 |
| B | HIS192 |
| B | TRP193 |
| B | 43J301 |
| B | HOH422 |
| B | HOH433 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue 43J A 301 |
| Chain | Residue |
| A | MET90 |
| A | ASP191 |
| A | HIS192 |
| A | TRP193 |
| A | LYS194 |
| A | ASP195 |
| A | ASP219 |
| A | ASN220 |
| A | GLU249 |
| A | MG302 |
| A | SAM303 |
| A | HOH417 |
| B | LEU64 |
| B | PRO69 |
| B | ARG151 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 302 |
| Chain | Residue |
| A | ASP191 |
| A | ASP219 |
| A | ASN220 |
| A | 43J301 |
| A | HOH417 |
| site_id | AC6 |
| Number of Residues | 20 |
| Details | binding site for residue SAM A 303 |
| Chain | Residue |
| A | MET90 |
| A | ASN91 |
| A | VAL92 |
| A | GLY116 |
| A | ALA117 |
| A | TYR118 |
| A | TYR121 |
| A | SER122 |
| A | ILE139 |
| A | GLU140 |
| A | ILE141 |
| A | GLY167 |
| A | SER169 |
| A | GLN170 |
| A | ASP191 |
| A | HIS192 |
| A | TRP193 |
| A | 43J301 |
| A | HOH418 |
| A | HOH431 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| B | VAL92 | |
| B | SER122 | |
| B | GLU140 | |
| B | ASP191 | |
| A | VAL92 | |
| A | SER122 | |
| A | GLU140 | |
| A | ASP191 | |
| Chain | Residue | Details |
| B | GLU114 | |
| B | ILE141 | |
| B | SER169 | |
| A | GLU114 | |
| A | ILE141 | |
| A | SER169 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | BINDING: |
| Chain | Residue | Details |
| B | GLY167 | |
| B | LYS194 | |
| B | ASN220 | |
| B | GLU249 | |
| A | GLY167 | |
| A | LYS194 | |
| A | ASN220 | |
| A | GLU249 | |
| Chain | Residue | Details |
| B | ASP219 | |
| A | ASP219 | |
