Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0006584 | biological_process | catecholamine metabolic process |
| A | 0008171 | molecular_function | O-methyltransferase activity |
| A | 0016206 | molecular_function | catechol O-methyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue 43H A 301 |
| Chain | Residue |
| A | ALA67 |
| A | ASN220 |
| A | LEU248 |
| A | GLU249 |
| A | MG302 |
| A | SAM303 |
| A | MES304 |
| A | HOH406 |
| A | PRO69 |
| A | TRP88 |
| A | PHE155 |
| A | ASP191 |
| A | HIS192 |
| A | TRP193 |
| A | LYS194 |
| A | ASP219 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 302 |
| Chain | Residue |
| A | ASP191 |
| A | ASP219 |
| A | ASN220 |
| A | 43H301 |
| A | HOH459 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for residue SAM A 303 |
| Chain | Residue |
| A | MET90 |
| A | ASN91 |
| A | VAL92 |
| A | GLY116 |
| A | ALA117 |
| A | TYR118 |
| A | TYR121 |
| A | SER122 |
| A | ILE139 |
| A | GLU140 |
| A | ILE141 |
| A | GLY167 |
| A | SER169 |
| A | GLN170 |
| A | ASP191 |
| A | HIS192 |
| A | TRP193 |
| A | 43H301 |
| A | HOH462 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue MES A 304 |
| Chain | Residue |
| A | GLY70 |
| A | ASP154 |
| A | PHE155 |
| A | GLY157 |
| A | 43H301 |
| A | HOH414 |
| A | HOH539 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01019","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18486144","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01019","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18486144","evidenceCode":"ECO:0000269"}]} |
