Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4XTS

Salmonella typhimurium AhpC T43A mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004601	molecular_function	peroxidase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006979	biological_process	response to oxidative stress
A	0008379	molecular_function	thioredoxin peroxidase activity
A	0016209	molecular_function	antioxidant activity
A	0016491	molecular_function	oxidoreductase activity
A	0033554	biological_process	cellular response to stress
A	0042744	biological_process	hydrogen peroxide catabolic process
A	0045454	biological_process	cell redox homeostasis
A	0051920	molecular_function	peroxiredoxin activity
A	0098869	biological_process	cellular oxidant detoxification
A	0102039	molecular_function	NADH-dependent peroxiredoxin activity
B	0004601	molecular_function	peroxidase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006979	biological_process	response to oxidative stress
B	0008379	molecular_function	thioredoxin peroxidase activity
B	0016209	molecular_function	antioxidant activity
B	0016491	molecular_function	oxidoreductase activity
B	0033554	biological_process	cellular response to stress
B	0042744	biological_process	hydrogen peroxide catabolic process
B	0045454	biological_process	cell redox homeostasis
B	0051920	molecular_function	peroxiredoxin activity
B	0098869	biological_process	cellular oxidant detoxification
B	0102039	molecular_function	NADH-dependent peroxiredoxin activity
C	0004601	molecular_function	peroxidase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006979	biological_process	response to oxidative stress
C	0008379	molecular_function	thioredoxin peroxidase activity
C	0016209	molecular_function	antioxidant activity
C	0016491	molecular_function	oxidoreductase activity
C	0033554	biological_process	cellular response to stress
C	0042744	biological_process	hydrogen peroxide catabolic process
C	0045454	biological_process	cell redox homeostasis
C	0051920	molecular_function	peroxiredoxin activity
C	0098869	biological_process	cellular oxidant detoxification
C	0102039	molecular_function	NADH-dependent peroxiredoxin activity
D	0004601	molecular_function	peroxidase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006979	biological_process	response to oxidative stress
D	0008379	molecular_function	thioredoxin peroxidase activity
D	0016209	molecular_function	antioxidant activity
D	0016491	molecular_function	oxidoreductase activity
D	0033554	biological_process	cellular response to stress
D	0042744	biological_process	hydrogen peroxide catabolic process
D	0045454	biological_process	cell redox homeostasis
D	0051920	molecular_function	peroxiredoxin activity
D	0098869	biological_process	cellular oxidant detoxification
D	0102039	molecular_function	NADH-dependent peroxiredoxin activity
E	0004601	molecular_function	peroxidase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006979	biological_process	response to oxidative stress
E	0008379	molecular_function	thioredoxin peroxidase activity
E	0016209	molecular_function	antioxidant activity
E	0016491	molecular_function	oxidoreductase activity
E	0033554	biological_process	cellular response to stress
E	0042744	biological_process	hydrogen peroxide catabolic process
E	0045454	biological_process	cell redox homeostasis
E	0051920	molecular_function	peroxiredoxin activity
E	0098869	biological_process	cellular oxidant detoxification
E	0102039	molecular_function	NADH-dependent peroxiredoxin activity
F	0004601	molecular_function	peroxidase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006979	biological_process	response to oxidative stress
F	0008379	molecular_function	thioredoxin peroxidase activity
F	0016209	molecular_function	antioxidant activity
F	0016491	molecular_function	oxidoreductase activity
F	0033554	biological_process	cellular response to stress
F	0042744	biological_process	hydrogen peroxide catabolic process
F	0045454	biological_process	cell redox homeostasis
F	0051920	molecular_function	peroxiredoxin activity
F	0098869	biological_process	cellular oxidant detoxification
F	0102039	molecular_function	NADH-dependent peroxiredoxin activity
G	0004601	molecular_function	peroxidase activity
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006979	biological_process	response to oxidative stress
G	0008379	molecular_function	thioredoxin peroxidase activity
G	0016209	molecular_function	antioxidant activity
G	0016491	molecular_function	oxidoreductase activity
G	0033554	biological_process	cellular response to stress
G	0042744	biological_process	hydrogen peroxide catabolic process
G	0045454	biological_process	cell redox homeostasis
G	0051920	molecular_function	peroxiredoxin activity
G	0098869	biological_process	cellular oxidant detoxification
G	0102039	molecular_function	NADH-dependent peroxiredoxin activity
H	0004601	molecular_function	peroxidase activity
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006979	biological_process	response to oxidative stress
H	0008379	molecular_function	thioredoxin peroxidase activity
H	0016209	molecular_function	antioxidant activity
H	0016491	molecular_function	oxidoreductase activity
H	0033554	biological_process	cellular response to stress
H	0042744	biological_process	hydrogen peroxide catabolic process
H	0045454	biological_process	cell redox homeostasis
H	0051920	molecular_function	peroxiredoxin activity
H	0098869	biological_process	cellular oxidant detoxification
H	0102039	molecular_function	NADH-dependent peroxiredoxin activity
I	0004601	molecular_function	peroxidase activity
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006979	biological_process	response to oxidative stress
I	0008379	molecular_function	thioredoxin peroxidase activity
I	0016209	molecular_function	antioxidant activity
I	0016491	molecular_function	oxidoreductase activity
I	0033554	biological_process	cellular response to stress
I	0042744	biological_process	hydrogen peroxide catabolic process
I	0045454	biological_process	cell redox homeostasis
I	0051920	molecular_function	peroxiredoxin activity
I	0098869	biological_process	cellular oxidant detoxification
I	0102039	molecular_function	NADH-dependent peroxiredoxin activity
J	0004601	molecular_function	peroxidase activity
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006979	biological_process	response to oxidative stress
J	0008379	molecular_function	thioredoxin peroxidase activity
J	0016209	molecular_function	antioxidant activity
J	0016491	molecular_function	oxidoreductase activity
J	0033554	biological_process	cellular response to stress
J	0042744	biological_process	hydrogen peroxide catabolic process
J	0045454	biological_process	cell redox homeostasis
J	0051920	molecular_function	peroxiredoxin activity
J	0098869	biological_process	cellular oxidant detoxification
J	0102039	molecular_function	NADH-dependent peroxiredoxin activity
K	0004601	molecular_function	peroxidase activity
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006979	biological_process	response to oxidative stress
K	0008379	molecular_function	thioredoxin peroxidase activity
K	0016209	molecular_function	antioxidant activity
K	0016491	molecular_function	oxidoreductase activity
K	0033554	biological_process	cellular response to stress
K	0042744	biological_process	hydrogen peroxide catabolic process
K	0045454	biological_process	cell redox homeostasis
K	0051920	molecular_function	peroxiredoxin activity
K	0098869	biological_process	cellular oxidant detoxification
K	0102039	molecular_function	NADH-dependent peroxiredoxin activity
L	0004601	molecular_function	peroxidase activity
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006979	biological_process	response to oxidative stress
L	0008379	molecular_function	thioredoxin peroxidase activity
L	0016209	molecular_function	antioxidant activity
L	0016491	molecular_function	oxidoreductase activity
L	0033554	biological_process	cellular response to stress
L	0042744	biological_process	hydrogen peroxide catabolic process
L	0045454	biological_process	cell redox homeostasis
L	0051920	molecular_function	peroxiredoxin activity
L	0098869	biological_process	cellular oxidant detoxification
L	0102039	molecular_function	NADH-dependent peroxiredoxin activity
M	0004601	molecular_function	peroxidase activity
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0006979	biological_process	response to oxidative stress
M	0008379	molecular_function	thioredoxin peroxidase activity
M	0016209	molecular_function	antioxidant activity
M	0016491	molecular_function	oxidoreductase activity
M	0033554	biological_process	cellular response to stress
M	0042744	biological_process	hydrogen peroxide catabolic process
M	0045454	biological_process	cell redox homeostasis
M	0051920	molecular_function	peroxiredoxin activity
M	0098869	biological_process	cellular oxidant detoxification
M	0102039	molecular_function	NADH-dependent peroxiredoxin activity
N	0004601	molecular_function	peroxidase activity
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0006979	biological_process	response to oxidative stress
N	0008379	molecular_function	thioredoxin peroxidase activity
N	0016209	molecular_function	antioxidant activity
N	0016491	molecular_function	oxidoreductase activity
N	0033554	biological_process	cellular response to stress
N	0042744	biological_process	hydrogen peroxide catabolic process
N	0045454	biological_process	cell redox homeostasis
N	0051920	molecular_function	peroxiredoxin activity
N	0098869	biological_process	cellular oxidant detoxification
N	0102039	molecular_function	NADH-dependent peroxiredoxin activity
O	0004601	molecular_function	peroxidase activity
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0006979	biological_process	response to oxidative stress
O	0008379	molecular_function	thioredoxin peroxidase activity
O	0016209	molecular_function	antioxidant activity
O	0016491	molecular_function	oxidoreductase activity
O	0033554	biological_process	cellular response to stress
O	0042744	biological_process	hydrogen peroxide catabolic process
O	0045454	biological_process	cell redox homeostasis
O	0051920	molecular_function	peroxiredoxin activity
O	0098869	biological_process	cellular oxidant detoxification
O	0102039	molecular_function	NADH-dependent peroxiredoxin activity
P	0004601	molecular_function	peroxidase activity
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0006979	biological_process	response to oxidative stress
P	0008379	molecular_function	thioredoxin peroxidase activity
P	0016209	molecular_function	antioxidant activity
P	0016491	molecular_function	oxidoreductase activity
P	0033554	biological_process	cellular response to stress
P	0042744	biological_process	hydrogen peroxide catabolic process
P	0045454	biological_process	cell redox homeostasis
P	0051920	molecular_function	peroxiredoxin activity
P	0098869	biological_process	cellular oxidant detoxification
P	0102039	molecular_function	NADH-dependent peroxiredoxin activity
Q	0004601	molecular_function	peroxidase activity
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0006979	biological_process	response to oxidative stress
Q	0008379	molecular_function	thioredoxin peroxidase activity
Q	0016209	molecular_function	antioxidant activity
Q	0016491	molecular_function	oxidoreductase activity
Q	0033554	biological_process	cellular response to stress
Q	0042744	biological_process	hydrogen peroxide catabolic process
Q	0045454	biological_process	cell redox homeostasis
Q	0051920	molecular_function	peroxiredoxin activity
Q	0098869	biological_process	cellular oxidant detoxification
Q	0102039	molecular_function	NADH-dependent peroxiredoxin activity
R	0004601	molecular_function	peroxidase activity
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0006979	biological_process	response to oxidative stress
R	0008379	molecular_function	thioredoxin peroxidase activity
R	0016209	molecular_function	antioxidant activity
R	0016491	molecular_function	oxidoreductase activity
R	0033554	biological_process	cellular response to stress
R	0042744	biological_process	hydrogen peroxide catabolic process
R	0045454	biological_process	cell redox homeostasis
R	0051920	molecular_function	peroxiredoxin activity
R	0098869	biological_process	cellular oxidant detoxification
R	0102039	molecular_function	NADH-dependent peroxiredoxin activity
S	0004601	molecular_function	peroxidase activity
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0006979	biological_process	response to oxidative stress
S	0008379	molecular_function	thioredoxin peroxidase activity
S	0016209	molecular_function	antioxidant activity
S	0016491	molecular_function	oxidoreductase activity
S	0033554	biological_process	cellular response to stress
S	0042744	biological_process	hydrogen peroxide catabolic process
S	0045454	biological_process	cell redox homeostasis
S	0051920	molecular_function	peroxiredoxin activity
S	0098869	biological_process	cellular oxidant detoxification
S	0102039	molecular_function	NADH-dependent peroxiredoxin activity
T	0004601	molecular_function	peroxidase activity
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0006979	biological_process	response to oxidative stress
T	0008379	molecular_function	thioredoxin peroxidase activity
T	0016209	molecular_function	antioxidant activity
T	0016491	molecular_function	oxidoreductase activity
T	0033554	biological_process	cellular response to stress
T	0042744	biological_process	hydrogen peroxide catabolic process
T	0045454	biological_process	cell redox homeostasis
T	0051920	molecular_function	peroxiredoxin activity
T	0098869	biological_process	cellular oxidant detoxification
T	0102039	molecular_function	NADH-dependent peroxiredoxin activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue CL A 202

Chain	Residue
A	ARG105
A	HOH301

site_id	AC2
Number of Residues	1
Details	binding site for residue CL B 201

Chain	Residue
B	LEU2

site_id	AC3
Number of Residues	3
Details	binding site for residue CL C 201

Chain	Residue
C	SER1
C	LEU2
C	HOH311

site_id	AC4
Number of Residues	1
Details	binding site for residue CL C 202

Chain	Residue
C	ARG105

site_id	AC5
Number of Residues	1
Details	binding site for residue CL D 201

Chain	Residue
D	LEU2

site_id	AC6
Number of Residues	1
Details	binding site for residue CL E 201

Chain	Residue
E	HOH314

site_id	AC7
Number of Residues	2
Details	binding site for residue CL F 201

Chain	Residue
F	SER1
F	LEU2

site_id	AC8
Number of Residues	1
Details	binding site for residue CL G 201

Chain	Residue
G	LEU2

site_id	AC9
Number of Residues	3
Details	binding site for residue CL H 201

Chain	Residue
H	SER1
H	LEU2
I	HOH306

site_id	AD1
Number of Residues	3
Details	binding site for residue CL H 202

Chain	Residue
G	HOH320
H	THR100
H	ARG105

site_id	AD2
Number of Residues	2
Details	binding site for residue CL I 201

Chain	Residue
I	LEU2
I	HOH301

site_id	AD3
Number of Residues	1
Details	binding site for residue CL J 201

Chain	Residue
J	ARG105

site_id	AD4
Number of Residues	2
Details	binding site for residue CL J 202

Chain	Residue
J	LEU2
J	HOH310

site_id	AD5
Number of Residues	3
Details	binding site for residue CL K 201

Chain	Residue
K	SER1
K	LEU2
K	HOH308

site_id	AD6
Number of Residues	3
Details	binding site for residue CL K 202

Chain	Residue
K	ARG105
K	MET110
P	HOH302

site_id	AD7
Number of Residues	3
Details	binding site for residue CL L 201

Chain	Residue
K	HOH308
L	SER1
L	LEU2

site_id	AD8
Number of Residues	1
Details	binding site for residue CL L 202

Chain	Residue
M	ARG105

site_id	AD9
Number of Residues	1
Details	binding site for residue CL M 201

Chain	Residue
M	LEU2

site_id	AE1
Number of Residues	2
Details	binding site for residue CL N 201

Chain	Residue
N	LEU2
N	HOH311

site_id	AE2
Number of Residues	1
Details	binding site for residue CL O 201

Chain	Residue
O	LEU2

site_id	AE3
Number of Residues	2
Details	binding site for residue CL O 202

Chain	Residue
N	ARG105
N	HOH314

site_id	AE4
Number of Residues	3
Details	binding site for residue CL P 201

Chain	Residue
P	SER1
P	LEU2
Q	HOH219

site_id	AE5
Number of Residues	2
Details	binding site for residue CL R 201

Chain	Residue
R	LEU2
R	ILE133

site_id	AE6
Number of Residues	4
Details	binding site for residue CL R 202

Chain	Residue
Q	HOH215
R	ARG105
R	MET110
R	HOH315

site_id	AE7
Number of Residues	2
Details	binding site for residue CL S 201

Chain	Residue
S	SER1
S	LEU2

site_id	AE8
Number of Residues	2
Details	binding site for residue CL T 201

Chain	Residue
T	SER1
T	LEU2

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	ACT_SITE: Cysteine sulfenic acid (-SOH) intermediate => ECO:0000305\|PubMed:18986167

Chain	Residue	Details
A	CYS46
J	CYS46
K	CYS46
L	CYS46
M	CYS46
N	CYS46
O	CYS46
P	CYS46
Q	CYS46
R	CYS46
S	CYS46
B	CYS46
T	CYS46
C	CYS46
D	CYS46
E	CYS46
F	CYS46
G	CYS46
H	CYS46
I	CYS46

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)