4XP7

Crystal structure of Human tRNA dihydrouridine synthase 2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008033	biological_process	tRNA processing
A	0017150	molecular_function	tRNA dihydrouridine synthase activity
A	0050660	molecular_function	flavin adenine dinucleotide binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue FNR A 401

Chain	Residue
A	ALA17
A	ASN214
A	GLY215
A	GLY216
A	SER217
A	ALA242
A	ARG243
A	HOH520
A	HOH586
A	PRO18
A	MET19
A	VAL20
A	GLU43
A	GLN87
A	ASN113
A	LYS155
A	HIS183

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Functional Information from PROSITE/UniProt

site_id	PS01136
Number of Residues	19
Details	UPF0034 Uncharacterized protein family UPF0034 signature. IDVNmGCPkqy.Stkggm.GA

Chain	Residue	Details
A	ILE110-ALA128

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26143927","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26429968","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4WFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XP7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26429968","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4WFS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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