Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| B | 0005576 | cellular_component | extracellular region |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | LYS164 |
| A | PRO168 |
| A | GLY169 |
| A | GLN233 |
| A | NA312 |
| A | HOH418 |
| A | HOH429 |
| A | HOH503 |
| A | HOH550 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | ASN34 |
| A | GLY36 |
| A | TYR37 |
| A | ILE70 |
| A | ASN71 |
| A | SER159 |
| A | SER161 |
| A | SER162 |
| A | EDO303 |
| A | HOH440 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | ARG64 |
| A | ILE70 |
| A | ASN71 |
| A | VAL73 |
| A | SER161 |
| A | SER162 |
| A | EDO302 |
| A | HOH416 |
| A | HOH471 |
| A | HOH507 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | CYS124 |
| A | ALA125 |
| A | PHE176 |
| A | GLN203 |
| A | LYS223 |
| A | CYS225 |
| A | EDO308 |
| A | HOH518 |
| A | HOH651 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | ASN92 |
| A | THR95 |
| A | ASN97 |
| A | HOH414 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | TYR20 |
| A | CYS22 |
| A | THR26 |
| A | HOH666 |
| A | HOH674 |
| A | HOH742 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | ILE45 |
| A | ASN46 |
| A | LYS232 |
| A | HOH621 |
| A | HOH678 |
| A | HOH708 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 308 |
| Chain | Residue |
| A | ALA127 |
| A | ILE157 |
| A | LEU158 |
| A | EDO304 |
| A | HOH411 |
| A | HOH631 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 309 |
| Chain | Residue |
| A | GLU67 |
| A | ASN69 |
| A | VAL72 |
| A | GLU77 |
| A | HOH506 |
| A | HOH507 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue NA A 310 |
| Chain | Residue |
| A | GLN214 |
| A | LYS215 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 311 |
| Chain | Residue |
| A | TYR37 |
| A | LYS58 |
| A | HOH402 |
| A | HOH476 |
| B | ILE7 |
| B | PRO8 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 312 |
| Chain | Residue |
| A | SO4301 |
| A | HOH462 |
| A | HOH570 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue NH4 A 313 |
| Chain | Residue |
| A | SER162 |
| A | HOH404 |
| A | HOH606 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL51-CYS56 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP186-VAL197 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 220 |
| Details | Domain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Reactive bond","evidences":[{"source":"UniProtKB","id":"P81705","evidenceCode":"ECO:0000250"}]} |
