Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4XKU

E coli BFR variant Y114F

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004322	molecular_function	ferroxidase activity
A	0005506	molecular_function	iron ion binding
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0006880	biological_process	intracellular sequestering of iron ion
A	0008199	molecular_function	ferric iron binding
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0020037	molecular_function	heme binding
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0046872	molecular_function	metal ion binding
A	0140315	molecular_function	iron ion sequestering activity
B	0004322	molecular_function	ferroxidase activity
B	0005506	molecular_function	iron ion binding
B	0005515	molecular_function	protein binding
B	0005829	cellular_component	cytosol
B	0006826	biological_process	iron ion transport
B	0006879	biological_process	intracellular iron ion homeostasis
B	0006880	biological_process	intracellular sequestering of iron ion
B	0008199	molecular_function	ferric iron binding
B	0016020	cellular_component	membrane
B	0016491	molecular_function	oxidoreductase activity
B	0020037	molecular_function	heme binding
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0046872	molecular_function	metal ion binding
B	0140315	molecular_function	iron ion sequestering activity
C	0004322	molecular_function	ferroxidase activity
C	0005506	molecular_function	iron ion binding
C	0005515	molecular_function	protein binding
C	0005829	cellular_component	cytosol
C	0006826	biological_process	iron ion transport
C	0006879	biological_process	intracellular iron ion homeostasis
C	0006880	biological_process	intracellular sequestering of iron ion
C	0008199	molecular_function	ferric iron binding
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0020037	molecular_function	heme binding
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0046872	molecular_function	metal ion binding
C	0140315	molecular_function	iron ion sequestering activity
D	0004322	molecular_function	ferroxidase activity
D	0005506	molecular_function	iron ion binding
D	0005515	molecular_function	protein binding
D	0005829	cellular_component	cytosol
D	0006826	biological_process	iron ion transport
D	0006879	biological_process	intracellular iron ion homeostasis
D	0006880	biological_process	intracellular sequestering of iron ion
D	0008199	molecular_function	ferric iron binding
D	0016020	cellular_component	membrane
D	0016491	molecular_function	oxidoreductase activity
D	0020037	molecular_function	heme binding
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0046872	molecular_function	metal ion binding
D	0140315	molecular_function	iron ion sequestering activity
E	0004322	molecular_function	ferroxidase activity
E	0005506	molecular_function	iron ion binding
E	0005515	molecular_function	protein binding
E	0005829	cellular_component	cytosol
E	0006826	biological_process	iron ion transport
E	0006879	biological_process	intracellular iron ion homeostasis
E	0006880	biological_process	intracellular sequestering of iron ion
E	0008199	molecular_function	ferric iron binding
E	0016020	cellular_component	membrane
E	0016491	molecular_function	oxidoreductase activity
E	0020037	molecular_function	heme binding
E	0042802	molecular_function	identical protein binding
E	0042803	molecular_function	protein homodimerization activity
E	0046872	molecular_function	metal ion binding
E	0140315	molecular_function	iron ion sequestering activity
F	0004322	molecular_function	ferroxidase activity
F	0005506	molecular_function	iron ion binding
F	0005515	molecular_function	protein binding
F	0005829	cellular_component	cytosol
F	0006826	biological_process	iron ion transport
F	0006879	biological_process	intracellular iron ion homeostasis
F	0006880	biological_process	intracellular sequestering of iron ion
F	0008199	molecular_function	ferric iron binding
F	0016020	cellular_component	membrane
F	0016491	molecular_function	oxidoreductase activity
F	0020037	molecular_function	heme binding
F	0042802	molecular_function	identical protein binding
F	0042803	molecular_function	protein homodimerization activity
F	0046872	molecular_function	metal ion binding
F	0140315	molecular_function	iron ion sequestering activity
G	0004322	molecular_function	ferroxidase activity
G	0005506	molecular_function	iron ion binding
G	0005515	molecular_function	protein binding
G	0005829	cellular_component	cytosol
G	0006826	biological_process	iron ion transport
G	0006879	biological_process	intracellular iron ion homeostasis
G	0006880	biological_process	intracellular sequestering of iron ion
G	0008199	molecular_function	ferric iron binding
G	0016020	cellular_component	membrane
G	0016491	molecular_function	oxidoreductase activity
G	0020037	molecular_function	heme binding
G	0042802	molecular_function	identical protein binding
G	0042803	molecular_function	protein homodimerization activity
G	0046872	molecular_function	metal ion binding
G	0140315	molecular_function	iron ion sequestering activity
H	0004322	molecular_function	ferroxidase activity
H	0005506	molecular_function	iron ion binding
H	0005515	molecular_function	protein binding
H	0005829	cellular_component	cytosol
H	0006826	biological_process	iron ion transport
H	0006879	biological_process	intracellular iron ion homeostasis
H	0006880	biological_process	intracellular sequestering of iron ion
H	0008199	molecular_function	ferric iron binding
H	0016020	cellular_component	membrane
H	0016491	molecular_function	oxidoreductase activity
H	0020037	molecular_function	heme binding
H	0042802	molecular_function	identical protein binding
H	0042803	molecular_function	protein homodimerization activity
H	0046872	molecular_function	metal ion binding
H	0140315	molecular_function	iron ion sequestering activity
I	0004322	molecular_function	ferroxidase activity
I	0005506	molecular_function	iron ion binding
I	0005515	molecular_function	protein binding
I	0005829	cellular_component	cytosol
I	0006826	biological_process	iron ion transport
I	0006879	biological_process	intracellular iron ion homeostasis
I	0006880	biological_process	intracellular sequestering of iron ion
I	0008199	molecular_function	ferric iron binding
I	0016020	cellular_component	membrane
I	0016491	molecular_function	oxidoreductase activity
I	0020037	molecular_function	heme binding
I	0042802	molecular_function	identical protein binding
I	0042803	molecular_function	protein homodimerization activity
I	0046872	molecular_function	metal ion binding
I	0140315	molecular_function	iron ion sequestering activity
J	0004322	molecular_function	ferroxidase activity
J	0005506	molecular_function	iron ion binding
J	0005515	molecular_function	protein binding
J	0005829	cellular_component	cytosol
J	0006826	biological_process	iron ion transport
J	0006879	biological_process	intracellular iron ion homeostasis
J	0006880	biological_process	intracellular sequestering of iron ion
J	0008199	molecular_function	ferric iron binding
J	0016020	cellular_component	membrane
J	0016491	molecular_function	oxidoreductase activity
J	0020037	molecular_function	heme binding
J	0042802	molecular_function	identical protein binding
J	0042803	molecular_function	protein homodimerization activity
J	0046872	molecular_function	metal ion binding
J	0140315	molecular_function	iron ion sequestering activity
K	0004322	molecular_function	ferroxidase activity
K	0005506	molecular_function	iron ion binding
K	0005515	molecular_function	protein binding
K	0005829	cellular_component	cytosol
K	0006826	biological_process	iron ion transport
K	0006879	biological_process	intracellular iron ion homeostasis
K	0006880	biological_process	intracellular sequestering of iron ion
K	0008199	molecular_function	ferric iron binding
K	0016020	cellular_component	membrane
K	0016491	molecular_function	oxidoreductase activity
K	0020037	molecular_function	heme binding
K	0042802	molecular_function	identical protein binding
K	0042803	molecular_function	protein homodimerization activity
K	0046872	molecular_function	metal ion binding
K	0140315	molecular_function	iron ion sequestering activity
L	0004322	molecular_function	ferroxidase activity
L	0005506	molecular_function	iron ion binding
L	0005515	molecular_function	protein binding
L	0005829	cellular_component	cytosol
L	0006826	biological_process	iron ion transport
L	0006879	biological_process	intracellular iron ion homeostasis
L	0006880	biological_process	intracellular sequestering of iron ion
L	0008199	molecular_function	ferric iron binding
L	0016020	cellular_component	membrane
L	0016491	molecular_function	oxidoreductase activity
L	0020037	molecular_function	heme binding
L	0042802	molecular_function	identical protein binding
L	0042803	molecular_function	protein homodimerization activity
L	0046872	molecular_function	metal ion binding
L	0140315	molecular_function	iron ion sequestering activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue SO4 B 201

Chain	Residue
B	ARG117
D	ARG117
D	HOH320
F	ARG117
B	HOH407
B	HOH425
B	HOH409
B	HOH361
B	HOH442
B	HOH377
B	HOH335
B	HOH346

site_id	AC2
Number of Residues	8
Details	binding site for residue SO4 D 201

Chain	Residue
A	HOH394
D	GLY145
D	LEU146
D	GLN147
D	HOH327
D	HOH330
D	HOH303
D	HOH333

site_id	AC3
Number of Residues	11
Details	binding site for residue SO4 E 201

Chain	Residue
A	ARG117
A	HOH318
E	ARG117
E	HOH361
E	HOH382
E	HOH434
E	HOH435
E	HOH466
I	ARG117
I	HOH225
I	HOH331

site_id	AC4
Number of Residues	6
Details	binding site for residue SO4 E 202

Chain	Residue
B	GLY145
B	LEU146
B	GLN147
B	HOH401
E	HOH310
E	HOH389

site_id	AC5
Number of Residues	4
Details	binding site for residue SO4 E 203

Chain	Residue
E	GLY145
E	LEU146
E	GLN147
E	HOH301

site_id	AC6
Number of Residues	7
Details	binding site for residue SO4 F 201

Chain	Residue
F	HOH356
F	HOH361
F	HOH421
F	HOH329
I	GLY145
I	LEU146
I	GLN147

site_id	AC7
Number of Residues	7
Details	binding site for residue SO4 F 202

Chain	Residue
C	HOH282
F	GLY145
F	LEU146
F	GLN147
F	HOH384
F	HOH452
F	HOH311

site_id	AC8
Number of Residues	12
Details	binding site for residue SO4 G 201

Chain	Residue
C	ARG117
C	HOH220
G	ARG117
G	HOH352
G	HOH384
G	HOH395
G	HOH420
G	HOH431
G	HOH434
G	HOH447
K	ARG117
K	HOH324

site_id	AC9
Number of Residues	10
Details	binding site for residue SO4 H 201

Chain	Residue
H	ARG117
H	HOH474
H	HOH495
H	HOH538
H	HOH518
J	ARG117
J	HOH218
L	ARG117
L	HOH415
L	HOH346

site_id	AD1
Number of Residues	7
Details	binding site for residue SO4 H 202

Chain	Residue
C	GLY145
C	LEU146
C	GLN147
H	HOH419
H	HOH421
H	HOH458
H	HOH471

site_id	AD2
Number of Residues	6
Details	binding site for residue SO4 H 203

Chain	Residue
H	GLY145
H	LEU146
H	GLN147
H	HOH454
H	HOH479
H	HOH408

site_id	AD3
Number of Residues	9
Details	binding site for residue SO4 K 201

Chain	Residue
D	HOH416
D	HOH406
K	GLY145
K	LEU146
K	GLN147
K	HOH341
K	HOH333
K	HOH301
K	HOH354

site_id	AD4
Number of Residues	6
Details	binding site for residue SO4 L 201

Chain	Residue
G	GLY145
G	LEU146
G	GLN147
L	HOH318
L	HOH327
L	HOH368

site_id	AD5
Number of Residues	6
Details	binding site for residue SO4 L 202

Chain	Residue
G	HOH385
L	GLY145
L	LEU146
L	GLN147
L	HOH319
L	HOH334

site_id	AD6
Number of Residues	4
Details	binding site for residue SO4 A 201

Chain	Residue
A	GLY145
A	LEU146
A	GLN147
A	HOH315

Functional Information from PROSITE/UniProt

site_id	PS00549
Number of Residues	19
Details	BACTERIOFERRITIN Bacterioferritin signature. MkGdtkVInyLnklLgneL

Chain	Residue	Details
A	MET1-LEU19

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	96
Details	BINDING: BINDING => ECO:0000255\|PROSITE-ProRule:PRU00085, ECO:0000269\|PubMed:17077480

Chain	Residue	Details
A	GLU18
B	HIS46
B	ASP50
B	GLU51
B	HIS54
B	GLU94
B	GLU127
B	HIS130
C	GLU18
C	HIS46
C	ASP50
A	HIS46
C	GLU51
C	HIS54
C	GLU94
C	GLU127
C	HIS130
D	GLU18
D	HIS46
D	ASP50
D	GLU51
D	HIS54
A	ASP50
D	GLU94
D	GLU127
D	HIS130
E	GLU18
E	HIS46
E	ASP50
E	GLU51
E	HIS54
E	GLU94
E	GLU127
A	GLU51
E	HIS130
F	GLU18
F	HIS46
F	ASP50
F	GLU51
F	HIS54
F	GLU94
F	GLU127
F	HIS130
G	GLU18
A	HIS54
G	HIS46
G	ASP50
G	GLU51
G	HIS54
G	GLU94
G	GLU127
G	HIS130
H	GLU18
H	HIS46
H	ASP50
A	GLU94
H	GLU51
H	HIS54
H	GLU94
H	GLU127
H	HIS130
I	GLU18
I	HIS46
I	ASP50
I	GLU51
I	HIS54
A	GLU127
I	GLU94
I	GLU127
I	HIS130
J	GLU18
J	HIS46
J	ASP50
J	GLU51
J	HIS54
J	GLU94
J	GLU127
A	HIS130
J	HIS130
K	GLU18
K	HIS46
K	ASP50
K	GLU51
K	HIS54
K	GLU94
K	GLU127
K	HIS130
L	GLU18
B	GLU18
L	HIS46
L	ASP50
L	GLU51
L	HIS54
L	GLU94
L	GLU127
L	HIS130

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: axial binding residue => ECO:0000255\|PROSITE-ProRule:PRU00085, ECO:0000269\|PubMed:17077480

Chain	Residue	Details
A	MET52
J	MET52
K	MET52
L	MET52
B	MET52
C	MET52
D	MET52
E	MET52
F	MET52
G	MET52
H	MET52
I	MET52

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)