4XKP

Crystal structure of NikA from Staphylococcus aureus in complex with Ni(L-His)2 (co-crystallization with Ni(II) and BHI medium supernatant)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0015675	biological_process	nickel cation transport
A	0015833	biological_process	peptide transport
A	0042597	cellular_component	periplasmic space
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0055085	biological_process	transmembrane transport
A	1904680	molecular_function	peptide transmembrane transporter activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue NI A 501

Chain	Residue
A	HIS502
A	HIS503

---

site_id	AC2
Number of Residues	11
Details	binding site for residue HIS A 502

Chain	Residue
A	SER370
A	NI501
A	HIS503
A	HOH777
A	LEU17
A	ARG234
A	TYR322
A	ARG325
A	ILE354
A	GLU355
A	TYR369

---

site_id	AC3
Number of Residues	12
Details	binding site for residue HIS A 503

Chain	Residue
A	PHE134
A	ARG234
A	GLU355
A	SER370
A	PHE371
A	GLY372
A	ILE393
A	NI501
A	HIS502
A	HOH896
A	HOH907
A	HOH1003

---

site_id	AC4
Number of Residues	4
Details	binding site for residue GOL A 504

Chain	Residue
A	LYS54
A	LYS69
A	ASP70
A	ASN402

---

site_id	AC5
Number of Residues	7
Details	binding site for residue GOL A 505

Chain	Residue
A	GLU83
A	ALA110
A	GLN295
A	ASP338
A	LYS341
A	HOH645
A	HOH662

---

site_id	AC6
Number of Residues	7
Details	binding site for residue EPE A 506

Chain	Residue
A	ILE48
A	GLU49
A	LYS50
A	TYR56
A	TYR101
A	ASP390
A	HOH630

---

site_id	AC7
Number of Residues	9
Details	binding site for residue GOL A 507

Chain	Residue
A	ASP256
A	ARG261
A	THR277
A	PRO290
A	LYS291
A	THR293
A	SER431
A	HOH733
A	HOH744

---

site_id	AC8
Number of Residues	9
Details	binding site for residue GOL A 508

Chain	Residue
A	LYS32
A	LYS456
A	GLY461
A	ILE462
A	TYR463
A	HOH767
A	HOH862
A	HOH948
A	HOH951

---

site_id	AC9
Number of Residues	6
Details	binding site for residue GOL A 509

Chain	Residue
A	ASP260
A	GLY263
A	HIS267
A	VAL334
A	HOH612
A	HOH740

---

site_id	AD1
Number of Residues	6
Details	binding site for residue GOL A 510

Chain	Residue
A	THR109
A	ALA110
A	LYS114
A	LEU115
A	THR116
A	LYS245

---

site_id	AD2
Number of Residues	4
Details	binding site for residue GOL A 511

Chain	Residue
A	LYS318
A	LYS349
A	TYR357
A	HOH602

---

site_id	AD3
Number of Residues	4
Details	binding site for residue GOL A 512

Chain	Residue
A	LYS226
A	LYS453
A	ASN454
A	TYR455

---

site_id	AD4
Number of Residues	7
Details	binding site for residue GOL A 513

Chain	Residue
A	LYS143
A	LYS349
A	VAL351
A	ASP352
A	ASP353
A	HOH607
A	HOH897

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