4XKM

Crystal structure of Xylose Isomerase from an human intestinal tract microbe Bacteroides thetaiotaomicron

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0005737	cellular_component	cytoplasm
A	0005975	biological_process	carbohydrate metabolic process
A	0009045	molecular_function	xylose isomerase activity
A	0016853	molecular_function	isomerase activity
A	0042732	biological_process	D-xylose metabolic process
A	0042843	biological_process	D-xylose catabolic process
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0005737	cellular_component	cytoplasm
B	0005975	biological_process	carbohydrate metabolic process
B	0009045	molecular_function	xylose isomerase activity
B	0016853	molecular_function	isomerase activity
B	0042732	biological_process	D-xylose metabolic process
B	0042843	biological_process	D-xylose catabolic process
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0005737	cellular_component	cytoplasm
C	0005975	biological_process	carbohydrate metabolic process
C	0009045	molecular_function	xylose isomerase activity
C	0016853	molecular_function	isomerase activity
C	0042732	biological_process	D-xylose metabolic process
C	0042843	biological_process	D-xylose catabolic process
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0005737	cellular_component	cytoplasm
D	0005975	biological_process	carbohydrate metabolic process
D	0009045	molecular_function	xylose isomerase activity
D	0016853	molecular_function	isomerase activity
D	0042732	biological_process	D-xylose metabolic process
D	0042843	biological_process	D-xylose catabolic process
D	0046872	molecular_function	metal ion binding
E	0000287	molecular_function	magnesium ion binding
E	0005737	cellular_component	cytoplasm
E	0005975	biological_process	carbohydrate metabolic process
E	0009045	molecular_function	xylose isomerase activity
E	0016853	molecular_function	isomerase activity
E	0042732	biological_process	D-xylose metabolic process
E	0042843	biological_process	D-xylose catabolic process
E	0046872	molecular_function	metal ion binding
F	0000287	molecular_function	magnesium ion binding
F	0005737	cellular_component	cytoplasm
F	0005975	biological_process	carbohydrate metabolic process
F	0009045	molecular_function	xylose isomerase activity
F	0016853	molecular_function	isomerase activity
F	0042732	biological_process	D-xylose metabolic process
F	0042843	biological_process	D-xylose catabolic process
F	0046872	molecular_function	metal ion binding
G	0000287	molecular_function	magnesium ion binding
G	0005737	cellular_component	cytoplasm
G	0005975	biological_process	carbohydrate metabolic process
G	0009045	molecular_function	xylose isomerase activity
G	0016853	molecular_function	isomerase activity
G	0042732	biological_process	D-xylose metabolic process
G	0042843	biological_process	D-xylose catabolic process
G	0046872	molecular_function	metal ion binding
H	0000287	molecular_function	magnesium ion binding
H	0005737	cellular_component	cytoplasm
H	0005975	biological_process	carbohydrate metabolic process
H	0009045	molecular_function	xylose isomerase activity
H	0016853	molecular_function	isomerase activity
H	0042732	biological_process	D-xylose metabolic process
H	0042843	biological_process	D-xylose catabolic process
H	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MN A 501

Chain	Residue
A	GLU234
A	GLU270
A	ASP298
A	ASP341
A	HOH761
A	HOH873

---

site_id	AC2
Number of Residues	4
Details	binding site for residue MN A 502

Chain	Residue
A	ASP311
A	GLU270
A	HIS273
A	ASP309

---

site_id	AC3
Number of Residues	6
Details	binding site for residue MN B 501

Chain	Residue
B	GLU234
B	GLU270
B	ASP298
B	ASP341
B	HOH769
B	HOH859

---

site_id	AC4
Number of Residues	4
Details	binding site for residue MN B 502

Chain	Residue
B	GLU270
B	HIS273
B	ASP309
B	ASP311

---

site_id	AC5
Number of Residues	5
Details	binding site for residue MN C 501

Chain	Residue
C	GLU234
C	GLU270
C	ASP298
C	ASP341
C	HOH752

---

site_id	AC6
Number of Residues	4
Details	binding site for residue MN C 502

Chain	Residue
C	GLU270
C	HIS273
C	ASP309
C	ASP311

---

site_id	AC7
Number of Residues	5
Details	binding site for residue MN D 501

Chain	Residue
D	GLU234
D	GLU270
D	ASP298
D	ASP341
D	HOH780

---

site_id	AC8
Number of Residues	4
Details	binding site for residue MN D 502

Chain	Residue
D	GLU270
D	HIS273
D	ASP309
D	ASP311

---

site_id	AC9
Number of Residues	5
Details	binding site for residue MN E 501

Chain	Residue
E	GLU234
E	GLU270
E	ASP298
E	ASP341
E	HOH720

---

site_id	AD1
Number of Residues	4
Details	binding site for residue MN E 502

Chain	Residue
E	GLU270
E	HIS273
E	ASP309
E	ASP311

---

site_id	AD2
Number of Residues	6
Details	binding site for residue MN F 501

Chain	Residue
F	GLU234
F	GLU270
F	ASP298
F	ASP341
F	HOH744
F	HOH821

---

site_id	AD3
Number of Residues	4
Details	binding site for residue MN F 502

Chain	Residue
F	GLU270
F	HIS273
F	ASP309
F	ASP311

---

site_id	AD4
Number of Residues	5
Details	binding site for residue MN G 501

Chain	Residue
G	GLU234
G	GLU270
G	ASP298
G	ASP341
G	HOH799

---

site_id	AD5
Number of Residues	4
Details	binding site for residue MN G 502

Chain	Residue
G	GLU270
G	HIS273
G	ASP309
G	ASP311

---

site_id	AD6
Number of Residues	6
Details	binding site for residue MN H 501

Chain	Residue
H	GLU234
H	GLU270
H	ASP298
H	ASP341
H	HOH758
H	HOH886

---

site_id	AD7
Number of Residues	4
Details	binding site for residue MN H 502

Chain	Residue
H	GLU270
H	HIS273
H	ASP309
H	ASP311

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00455","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	56
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00455","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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