4XKM
Crystal structure of Xylose Isomerase from an human intestinal tract microbe Bacteroides thetaiotaomicron
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0009045 | molecular_function | xylose isomerase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0042732 | biological_process | D-xylose metabolic process |
| A | 0042843 | biological_process | D-xylose catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0009045 | molecular_function | xylose isomerase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0042732 | biological_process | D-xylose metabolic process |
| B | 0042843 | biological_process | D-xylose catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0009045 | molecular_function | xylose isomerase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0042732 | biological_process | D-xylose metabolic process |
| C | 0042843 | biological_process | D-xylose catabolic process |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0009045 | molecular_function | xylose isomerase activity |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0042732 | biological_process | D-xylose metabolic process |
| D | 0042843 | biological_process | D-xylose catabolic process |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0000287 | molecular_function | magnesium ion binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005975 | biological_process | carbohydrate metabolic process |
| E | 0009045 | molecular_function | xylose isomerase activity |
| E | 0016853 | molecular_function | isomerase activity |
| E | 0042732 | biological_process | D-xylose metabolic process |
| E | 0042843 | biological_process | D-xylose catabolic process |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0000287 | molecular_function | magnesium ion binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005975 | biological_process | carbohydrate metabolic process |
| F | 0009045 | molecular_function | xylose isomerase activity |
| F | 0016853 | molecular_function | isomerase activity |
| F | 0042732 | biological_process | D-xylose metabolic process |
| F | 0042843 | biological_process | D-xylose catabolic process |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0000287 | molecular_function | magnesium ion binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005975 | biological_process | carbohydrate metabolic process |
| G | 0009045 | molecular_function | xylose isomerase activity |
| G | 0016853 | molecular_function | isomerase activity |
| G | 0042732 | biological_process | D-xylose metabolic process |
| G | 0042843 | biological_process | D-xylose catabolic process |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0000287 | molecular_function | magnesium ion binding |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0005975 | biological_process | carbohydrate metabolic process |
| H | 0009045 | molecular_function | xylose isomerase activity |
| H | 0016853 | molecular_function | isomerase activity |
| H | 0042732 | biological_process | D-xylose metabolic process |
| H | 0042843 | biological_process | D-xylose catabolic process |
| H | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 501 |
| Chain | Residue |
| A | GLU234 |
| A | GLU270 |
| A | ASP298 |
| A | ASP341 |
| A | HOH761 |
| A | HOH873 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MN A 502 |
| Chain | Residue |
| A | ASP311 |
| A | GLU270 |
| A | HIS273 |
| A | ASP309 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MN B 501 |
| Chain | Residue |
| B | GLU234 |
| B | GLU270 |
| B | ASP298 |
| B | ASP341 |
| B | HOH769 |
| B | HOH859 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue MN B 502 |
| Chain | Residue |
| B | GLU270 |
| B | HIS273 |
| B | ASP309 |
| B | ASP311 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MN C 501 |
| Chain | Residue |
| C | GLU234 |
| C | GLU270 |
| C | ASP298 |
| C | ASP341 |
| C | HOH752 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue MN C 502 |
| Chain | Residue |
| C | GLU270 |
| C | HIS273 |
| C | ASP309 |
| C | ASP311 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue MN D 501 |
| Chain | Residue |
| D | GLU234 |
| D | GLU270 |
| D | ASP298 |
| D | ASP341 |
| D | HOH780 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue MN D 502 |
| Chain | Residue |
| D | GLU270 |
| D | HIS273 |
| D | ASP309 |
| D | ASP311 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue MN E 501 |
| Chain | Residue |
| E | GLU234 |
| E | GLU270 |
| E | ASP298 |
| E | ASP341 |
| E | HOH720 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue MN E 502 |
| Chain | Residue |
| E | GLU270 |
| E | HIS273 |
| E | ASP309 |
| E | ASP311 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue MN F 501 |
| Chain | Residue |
| F | GLU234 |
| F | GLU270 |
| F | ASP298 |
| F | ASP341 |
| F | HOH744 |
| F | HOH821 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue MN F 502 |
| Chain | Residue |
| F | GLU270 |
| F | HIS273 |
| F | ASP309 |
| F | ASP311 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue MN G 501 |
| Chain | Residue |
| G | GLU234 |
| G | GLU270 |
| G | ASP298 |
| G | ASP341 |
| G | HOH799 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue MN G 502 |
| Chain | Residue |
| G | GLU270 |
| G | HIS273 |
| G | ASP309 |
| G | ASP311 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue MN H 501 |
| Chain | Residue |
| H | GLU234 |
| H | GLU270 |
| H | ASP298 |
| H | ASP341 |
| H | HOH758 |
| H | HOH886 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue MN H 502 |
| Chain | Residue |
| H | GLU270 |
| H | HIS273 |
| H | ASP309 |
| H | ASP311 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00455 |
| Chain | Residue | Details |
| A | HIS103 | |
| E | ASP106 | |
| F | HIS103 | |
| F | ASP106 | |
| G | HIS103 | |
| G | ASP106 | |
| H | HIS103 | |
| H | ASP106 | |
| A | ASP106 | |
| B | HIS103 | |
| B | ASP106 | |
| C | HIS103 | |
| C | ASP106 | |
| D | HIS103 | |
| D | ASP106 | |
| E | HIS103 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 56 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00455 |
| Chain | Residue | Details |
| A | GLU234 | |
| B | HIS273 | |
| B | ASP298 | |
| B | ASP309 | |
| B | ASP311 | |
| B | ASP341 | |
| C | GLU234 | |
| C | GLU270 | |
| C | HIS273 | |
| C | ASP298 | |
| C | ASP309 | |
| A | GLU270 | |
| C | ASP311 | |
| C | ASP341 | |
| D | GLU234 | |
| D | GLU270 | |
| D | HIS273 | |
| D | ASP298 | |
| D | ASP309 | |
| D | ASP311 | |
| D | ASP341 | |
| E | GLU234 | |
| A | HIS273 | |
| E | GLU270 | |
| E | HIS273 | |
| E | ASP298 | |
| E | ASP309 | |
| E | ASP311 | |
| E | ASP341 | |
| F | GLU234 | |
| F | GLU270 | |
| F | HIS273 | |
| F | ASP298 | |
| A | ASP298 | |
| F | ASP309 | |
| F | ASP311 | |
| F | ASP341 | |
| G | GLU234 | |
| G | GLU270 | |
| G | HIS273 | |
| G | ASP298 | |
| G | ASP309 | |
| G | ASP311 | |
| G | ASP341 | |
| A | ASP309 | |
| H | GLU234 | |
| H | GLU270 | |
| H | HIS273 | |
| H | ASP298 | |
| H | ASP309 | |
| H | ASP311 | |
| H | ASP341 | |
| A | ASP311 | |
| A | ASP341 | |
| B | GLU234 | |
| B | GLU270 |
