Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4XK9

Crystal structure of A-AChBP in complex with pinnatoxin G

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
F	0004888	molecular_function	transmembrane signaling receptor activity
F	0005216	molecular_function	monoatomic ion channel activity
F	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
F	0006811	biological_process	monoatomic ion transport
F	0016020	cellular_component	membrane
F	0034220	biological_process	monoatomic ion transmembrane transport
G	0004888	molecular_function	transmembrane signaling receptor activity
G	0005216	molecular_function	monoatomic ion channel activity
G	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
G	0006811	biological_process	monoatomic ion transport
G	0016020	cellular_component	membrane
G	0034220	biological_process	monoatomic ion transmembrane transport
H	0004888	molecular_function	transmembrane signaling receptor activity
H	0005216	molecular_function	monoatomic ion channel activity
H	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
H	0006811	biological_process	monoatomic ion transport
H	0016020	cellular_component	membrane
H	0034220	biological_process	monoatomic ion transmembrane transport
I	0004888	molecular_function	transmembrane signaling receptor activity
I	0005216	molecular_function	monoatomic ion channel activity
I	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
I	0006811	biological_process	monoatomic ion transport
I	0016020	cellular_component	membrane
I	0034220	biological_process	monoatomic ion transmembrane transport
J	0004888	molecular_function	transmembrane signaling receptor activity
J	0005216	molecular_function	monoatomic ion channel activity
J	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
J	0006811	biological_process	monoatomic ion transport
J	0016020	cellular_component	membrane
J	0034220	biological_process	monoatomic ion transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue 41J A 301

Chain	Residue
A	TYR93
E	TYR55
E	ILE118
E	ASP164
E	SER167
E	HOH450
A	SER146
A	TRP147
A	VAL148
A	TYR188
A	TYR195
A	HOH413
A	HOH472
E	THR36

site_id	AC2
Number of Residues	3
Details	binding site for residue CL A 302

Chain	Residue
A	MET19
A	ILE85
A	TRP86

site_id	AC3
Number of Residues	13
Details	binding site for residue 41J B 301

Chain	Residue
A	THR36
A	TYR55
A	ARG79
A	SER167
A	HOH408
B	TYR93
B	SER146
B	TRP147
B	VAL148
B	TYR188
B	TYR195
B	HOH450
B	HOH465

site_id	AC4
Number of Residues	2
Details	binding site for residue CL B 302

Chain	Residue
B	MET19
B	TRP86

site_id	AC5
Number of Residues	14
Details	binding site for residue 41J C 301

Chain	Residue
B	THR36
B	TYR55
B	ILE118
B	SER167
B	HOH405
C	TYR93
C	SER146
C	TRP147
C	VAL148
C	TYR188
C	CYS190
C	TYR195
C	HOH434
C	HOH449

site_id	AC6
Number of Residues	3
Details	binding site for residue CL C 302

Chain	Residue
C	MET19
C	ILE85
C	TRP86

site_id	AC7
Number of Residues	12
Details	binding site for residue 41J D 301

Chain	Residue
C	THR36
C	TYR55
C	ARG79
C	SER167
D	TYR93
D	SER146
D	TRP147
D	VAL148
D	TYR188
D	TYR195
D	HOH440
D	HOH447

site_id	AC8
Number of Residues	10
Details	binding site for residue 41J E 301

Chain	Residue
D	THR36
D	ILE118
D	HOH415
E	TYR93
E	SER146
E	TRP147
E	VAL148
E	TYR188
E	TYR195
E	HOH461

site_id	AC9
Number of Residues	1
Details	binding site for residue CL E 302

Chain	Residue
E	TRP86

site_id	AD1
Number of Residues	10
Details	binding site for residue 41J F 301

Chain	Residue
F	TYR93
F	SER146
F	TRP147
F	VAL148
F	TYR188
F	TYR195
J	THR36
J	TYR55
J	ILE118
J	SER167

site_id	AD2
Number of Residues	10
Details	binding site for residue 41J G 301

Chain	Residue
F	THR36
F	TYR55
F	HOH412
G	TYR93
G	SER146
G	TRP147
G	VAL148
G	TYR188
G	TYR195
G	HOH484

site_id	AD3
Number of Residues	2
Details	binding site for residue CL G 302

Chain	Residue
G	MET19
G	TRP86

site_id	AD4
Number of Residues	12
Details	binding site for residue 41J H 301

Chain	Residue
H	TYR93
H	SER146
H	TRP147
H	VAL148
H	TYR188
H	TYR195
H	HOH462
G	THR36
G	TYR55
G	ILE118
G	SER167
G	HOH431

site_id	AD5
Number of Residues	2
Details	binding site for residue CL H 302

Chain	Residue
H	TRP86
H	HOH442

site_id	AD6
Number of Residues	11
Details	binding site for residue 41J I 301

Chain	Residue
H	THR36
H	ARG79
H	ILE118
H	SER167
H	HOH447
I	TYR93
I	SER146
I	TRP147
I	VAL148
I	TYR188
I	TYR195

site_id	AD7
Number of Residues	10
Details	binding site for residue 41J J 301

Chain	Residue
I	THR36
I	TYR55
I	ILE118
J	TYR93
J	SER146
J	TRP147
J	VAL148
J	TYR188
J	TYR195
J	HOH416

site_id	AD8
Number of Residues	2
Details	binding site for residue CL J 302

Chain	Residue
J	MET19
J	TRP86

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)