4XK4

E. coli transcriptional regulator RUTR with dihydrouracil

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005515	molecular_function	protein binding
A	0006355	biological_process	regulation of DNA-templated transcription
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0045893	biological_process	positive regulation of DNA-templated transcription
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0005515	molecular_function	protein binding
B	0006355	biological_process	regulation of DNA-templated transcription
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0045893	biological_process	positive regulation of DNA-templated transcription
C	0000976	molecular_function	transcription cis-regulatory region binding
C	0003677	molecular_function	DNA binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0005515	molecular_function	protein binding
C	0006355	biological_process	regulation of DNA-templated transcription
C	0045892	biological_process	negative regulation of DNA-templated transcription
C	0045893	biological_process	positive regulation of DNA-templated transcription
D	0000976	molecular_function	transcription cis-regulatory region binding
D	0003677	molecular_function	DNA binding
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0005515	molecular_function	protein binding
D	0006355	biological_process	regulation of DNA-templated transcription
D	0045892	biological_process	negative regulation of DNA-templated transcription
D	0045893	biological_process	positive regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue DUC A 300

Chain	Residue
A	LEU74
A	TRP77
A	LYS101
A	TRP167
A	GLN171
A	HOH401
B	PHE176
B	GLN179

---

site_id	AC2
Number of Residues	8
Details	binding site for residue DUC B 300

Chain	Residue
A	GLN179
B	TRP77
B	LEU78
B	LYS101
B	TRP167
B	GLN171
B	HOH401
A	PHE176

---

site_id	AC3
Number of Residues	9
Details	binding site for residue DUC C 300

Chain	Residue
C	LEU74
C	TRP77
C	LYS101
C	PHE115
C	TRP167
C	GLN171
C	HOH401
D	PHE176
D	GLN179

---

site_id	AC4
Number of Residues	8
Details	binding site for residue DUC D 300

Chain	Residue
C	PHE176
C	GLN179
D	TRP77
D	LEU78
D	LYS101
D	TRP167
D	GLN171
D	HOH401

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	76
Details	DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00335

Chain	Residue	Details
A	THR39-TYR58
B	THR39-TYR58
C	THR39-TYR58
D	THR39-TYR58

---