4XK1
Crystal Structure of a Phosphoserine/phosphohydroxythreonine Aminotransferase (PSAT) from Pseudomonas aeruginosa with cofactor Pyridoxal Phosphate and bound Glutamate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004648 | molecular_function | O-phospho-L-serine:2-oxoglutarate aminotransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006563 | biological_process | L-serine metabolic process |
| A | 0006564 | biological_process | L-serine biosynthetic process |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0008615 | biological_process | pyridoxine biosynthetic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0004648 | molecular_function | O-phospho-L-serine:2-oxoglutarate aminotransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006563 | biological_process | L-serine metabolic process |
| B | 0006564 | biological_process | L-serine biosynthetic process |
| B | 0008483 | molecular_function | transaminase activity |
| B | 0008615 | biological_process | pyridoxine biosynthetic process |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue FMT A 401 |
| Chain | Residue |
| A | GLY34 |
| A | GLU39 |
| B | ASP17 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue FMT A 402 |
| Chain | Residue |
| A | PRO291 |
| A | ARG294 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue FMT B 401 |
| Chain | Residue |
| B | HOH532 |
| B | HOH534 |
| B | PRO163 |
| B | GLU164 |
| B | THR165 |
| B | ARG187 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue GLU B 402 |
| Chain | Residue |
| A | PHE6 |
| A | ASP17 |
| B | LEU28 |
| B | GLY34 |
| B | GLU39 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00160 |
| Chain | Residue | Details |
| A | ARG43 | |
| B | TRP103 | |
| B | THR153 | |
| B | ASP173 | |
| B | GLN196 | |
| B | ASN238 | |
| A | ALA77 | |
| A | TRP103 | |
| A | THR153 | |
| A | ASP173 | |
| A | GLN196 | |
| A | ASN238 | |
| B | ARG43 | |
| B | ALA77 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000255|HAMAP-Rule:MF_00160 |
| Chain | Residue | Details |
| A | LLP197 | |
| B | LLP197 |
