4XJT
Human CD38 complexed with inhibitor 2 [4-[(2,6-dimethylbenzyl)amino]-2-methylquinoline-8-carboxamide]
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0061809 | molecular_function | NAD+ nucleosidase activity, cyclic ADP-ribose generating |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue 41Z A 401 |
| Chain | Residue |
| A | LYS129 |
| A | GLU146 |
| A | ASP155 |
| A | SER186 |
| A | TRP189 |
| A | THR221 |
| A | NA7402 |
| A | HOH523 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue NA7 A 402 |
| Chain | Residue |
| A | SER126 |
| A | ARG127 |
| A | TRP176 |
| A | SER193 |
| A | ASP219 |
| A | SER220 |
| A | THR221 |
| A | PHE222 |
| A | GLN226 |
| A | 41Z401 |
| A | HOH521 |
| A | HOH536 |
| A | HOH537 |
| A | HOH539 |
| A | TRP125 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"7961800","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
