4XJ3
Crystal structure of Vibrio cholerae DncV GTP bound form
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0140701 | molecular_function | 3',3'-cyclic GMP-AMP synthase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | binding site for residue MG A 1001 |
Chain | Residue |
A | ASP131 |
A | ASP133 |
A | MG1002 |
A | GTP1012 |
A | HOH1320 |
site_id | AC2 |
Number of Residues | 7 |
Details | binding site for residue MG A 1002 |
Chain | Residue |
A | HOH1322 |
A | HOH1323 |
A | HOH1327 |
A | ASP131 |
A | MG1001 |
A | GTP1012 |
A | GTP1013 |
site_id | AC3 |
Number of Residues | 7 |
Details | binding site for residue EDO A 1003 |
Chain | Residue |
A | LYS277 |
A | HIS278 |
A | LYS281 |
A | ASP318 |
A | ALA319 |
A | SER320 |
A | HOH1110 |
site_id | AC4 |
Number of Residues | 6 |
Details | binding site for residue EDO A 1004 |
Chain | Residue |
A | ALA292 |
A | GLN293 |
A | ASN394 |
A | MET395 |
A | GLY398 |
A | HOH1230 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue EDO A 1005 |
Chain | Residue |
A | ARG290 |
A | GLY297 |
A | GLY298 |
A | HOH1271 |
site_id | AC6 |
Number of Residues | 5 |
Details | binding site for residue EDO A 1006 |
Chain | Residue |
A | TRP267 |
A | ALA306 |
A | ASN310 |
A | GLU342 |
A | PRO344 |
site_id | AC7 |
Number of Residues | 2 |
Details | binding site for residue EDO A 1007 |
Chain | Residue |
A | HIS317 |
A | GLU324 |
site_id | AC8 |
Number of Residues | 4 |
Details | binding site for residue EDO A 1008 |
Chain | Residue |
A | GLU129 |
A | ASP291 |
A | GTP1012 |
A | HOH1210 |
site_id | AC9 |
Number of Residues | 6 |
Details | binding site for residue EDO A 1009 |
Chain | Residue |
A | MET3 |
A | TRP5 |
A | GLU381 |
A | SER382 |
A | ALA383 |
A | LEU409 |
site_id | AD1 |
Number of Residues | 6 |
Details | binding site for residue EDO A 1010 |
Chain | Residue |
A | PHE64 |
A | TRP294 |
A | ASP295 |
A | VAL296 |
A | HOH1122 |
A | HOH1203 |
site_id | AD2 |
Number of Residues | 8 |
Details | binding site for residue EDO A 1011 |
Chain | Residue |
A | LEU24 |
A | LYS29 |
A | PHE115 |
A | ASP118 |
A | LEU120 |
A | ARG284 |
A | HOH1189 |
A | HOH1332 |
site_id | AD3 |
Number of Residues | 27 |
Details | binding site for residue GTP A 1012 |
Chain | Residue |
A | GLN112 |
A | GLY113 |
A | SER114 |
A | TYR117 |
A | ASP131 |
A | ASP133 |
A | PRO261 |
A | LYS287 |
A | SER301 |
A | ASP348 |
A | LEU352 |
A | MG1001 |
A | MG1002 |
A | EDO1008 |
A | GTP1013 |
A | HOH1190 |
A | HOH1206 |
A | HOH1215 |
A | HOH1268 |
A | HOH1292 |
A | HOH1301 |
A | HOH1314 |
A | HOH1321 |
A | HOH1322 |
A | HOH1326 |
A | HOH1327 |
A | HOH1363 |
site_id | AD4 |
Number of Residues | 14 |
Details | binding site for residue GTP A 1013 |
Chain | Residue |
A | HOH1324 |
A | HOH1352 |
A | GLN112 |
A | ASP131 |
A | ASP133 |
A | LYS177 |
A | THR179 |
A | CYS180 |
A | ARG182 |
A | ASP193 |
A | TYR197 |
A | SER259 |
A | MG1002 |
A | GTP1012 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | BINDING: BINDING => ECO:0000269|PubMed:25131990, ECO:0000269|PubMed:25201413, ECO:0000269|PubMed:25865248, ECO:0007744|PDB:4U03, ECO:0007744|PDB:4U0M, ECO:0007744|PDB:4XJ3, ECO:0007744|PDB:4XJ4, ECO:0007744|PDB:4XJ5 |
Chain | Residue | Details |
A | GLN112 | |
A | LYS287 | |
A | SER301 |
site_id | SWS_FT_FI2 |
Number of Residues | 3 |
Details | BINDING: BINDING => ECO:0000269|PubMed:25131990, ECO:0000269|PubMed:25201413, ECO:0000269|PubMed:25865248, ECO:0007744|PDB:4TXY, ECO:0007744|PDB:4TXZ, ECO:0007744|PDB:4TY0, ECO:0007744|PDB:4U03, ECO:0007744|PDB:4U0N, ECO:0007744|PDB:4XJ5 |
Chain | Residue | Details |
A | ASP131 | |
A | ASP133 | |
A | ASP193 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:25131990, ECO:0000269|PubMed:25201413, ECO:0007744|PDB:4U0M |
Chain | Residue | Details |
A | ARG182 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:25131990, ECO:0000269|PubMed:25201413, ECO:0007744|PDB:4U03, ECO:0007744|PDB:4XJ3, ECO:0007744|PDB:4XJ4, ECO:0007744|PDB:4XJ5 |
Chain | Residue | Details |
A | SER259 |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:25131990, ECO:0000269|PubMed:25201413, ECO:0000269|PubMed:25865248, ECO:0007744|PDB:4U03, ECO:0007744|PDB:4U0M, ECO:0007744|PDB:4XJ3, ECO:0007744|PDB:4XJ5 |
Chain | Residue | Details |
A | ASP348 |