4XIC

ANTPHD WITH 15BP di-thioate modified DNA DUPLEX

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
A	0003677	molecular_function	DNA binding
A	0006355	biological_process	regulation of DNA-templated transcription
D	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
D	0003677	molecular_function	DNA binding
D	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue NI B 101

Chain	Residue
B	DG1
C	HOH202

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site_id	AC2
Number of Residues	2
Details	binding site for residue MPD C 101

Chain	Residue
A	TYR25
C	DC37

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site_id	AC3
Number of Residues	1
Details	binding site for residue MPD D 101

Chain	Residue
F	MPD101

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site_id	AC4
Number of Residues	2
Details	binding site for residue NI D 102

Chain	Residue
A	HIS21
D	HIS21

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site_id	AC5
Number of Residues	1
Details	binding site for residue NI E 101

Chain	Residue
E	DG1

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site_id	AC6
Number of Residues	2
Details	binding site for residue MPD F 101

Chain	Residue
F	DC37
D	MPD101

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site_id	AC7
Number of Residues	8
Details	binding site for Di-nucleotide DC E 6 and C2S E 7

Chain	Residue
D	TYR25
D	GLN50
D	ARG53
D	MET54
E	DG5
E	DA8
F	DG31
F	DG32

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site_id	AC8
Number of Residues	7
Details	binding site for Di-nucleotide C2S E 7 and DA E 8

Chain	Residue
D	MET54
E	DC6
E	DT9
F	DA29
F	DT30
F	DG31
F	DG32

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Functional Information from PROSITE/UniProt

site_id	PS00027
Number of Residues	24
Details	HOMEOBOX_1 'Homeobox' domain signature. IAhaLsLTerQIKIWFqNrrmkwK

Chain	Residue	Details
A	ILE34-LYS57

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	118
Details	DNA_BIND: Homeobox => ECO:0000255|PROSITE-ProRule:PRU00108

Chain	Residue	Details
A	ARG1-ASN60
D	ARG1-ASN60

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