4XHZ

Crystal Structure of Human Protocadherin-15 EC8-10

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0007156	biological_process	homophilic cell-cell adhesion
A	0016020	cellular_component	membrane
A	0098609	biological_process	cell-cell adhesion

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CA A 2001

Chain	Residue
A	ASN899
A	TYR901
A	ASP931
A	ASP933
A	ALA939
A	ASP989

---

site_id	AC2
Number of Residues	5
Details	binding site for residue CA A 2002

Chain	Residue
A	MET898
A	ASP900
A	GLU809
A	GLU862
A	ASP897

---

site_id	AC3
Number of Residues	5
Details	binding site for residue CA A 2003

Chain	Residue
A	GLU809
A	ASP860
A	GLU862
A	ASP900
A	HOH2168

---

site_id	AC4
Number of Residues	3
Details	binding site for residue CL A 2004

Chain	Residue
A	VAL946
A	VAL960
A	ARG970

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	106
Details	Domain: {"description":"Cadherin 8","evidences":[{"source":"PROSITE-ProRule","id":"PRU00043","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	108
Details	Domain: {"description":"Cadherin 9","evidences":[{"source":"PROSITE-ProRule","id":"PRU00043","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	107
Details	Domain: {"description":"Cadherin 10","evidences":[{"source":"PROSITE-ProRule","id":"PRU00043","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---