Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4XHE

Crystal Structure of A-AChBP in complex with pinnatoxin A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
F	0004888	molecular_function	transmembrane signaling receptor activity
F	0005216	molecular_function	monoatomic ion channel activity
F	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
F	0006811	biological_process	monoatomic ion transport
F	0016020	cellular_component	membrane
F	0034220	biological_process	monoatomic ion transmembrane transport
G	0004888	molecular_function	transmembrane signaling receptor activity
G	0005216	molecular_function	monoatomic ion channel activity
G	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
G	0006811	biological_process	monoatomic ion transport
G	0016020	cellular_component	membrane
G	0034220	biological_process	monoatomic ion transmembrane transport
H	0004888	molecular_function	transmembrane signaling receptor activity
H	0005216	molecular_function	monoatomic ion channel activity
H	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
H	0006811	biological_process	monoatomic ion transport
H	0016020	cellular_component	membrane
H	0034220	biological_process	monoatomic ion transmembrane transport
I	0004888	molecular_function	transmembrane signaling receptor activity
I	0005216	molecular_function	monoatomic ion channel activity
I	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
I	0006811	biological_process	monoatomic ion transport
I	0016020	cellular_component	membrane
I	0034220	biological_process	monoatomic ion transmembrane transport
J	0004888	molecular_function	transmembrane signaling receptor activity
J	0005216	molecular_function	monoatomic ion channel activity
J	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
J	0006811	biological_process	monoatomic ion transport
J	0016020	cellular_component	membrane
J	0034220	biological_process	monoatomic ion transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue 40P A 301

Chain	Residue
A	TYR93
A	HOH502
A	HOH542
E	THR36
E	TYR55
E	ILE118
E	ASP164
E	SER167
E	HOH435
A	SER146
A	TRP147
A	VAL148
A	TYR188
A	TYR195
A	HOH477
A	HOH481
A	HOH482

site_id	AC2
Number of Residues	17
Details	binding site for residue 40P B 301

Chain	Residue
A	THR36
A	TYR55
A	ILE118
A	ASP164
A	SER167
A	HOH448
B	TYR93
B	SER146
B	TRP147
B	VAL148
B	TYR188
B	TYR195
B	HOH497
B	HOH519
B	HOH523
B	HOH554
B	HOH555

site_id	AC3
Number of Residues	6
Details	binding site for residue CA B 302

Chain	Residue
B	ASP-2
B	LYS-6
B	ASP-3
B	ASN70
B	HOH487
B	HOH517

site_id	AC4
Number of Residues	20
Details	binding site for residue 40P C 301

Chain	Residue
B	THR36
B	TYR55
B	ILE118
B	ASP164
B	SER167
C	TYR93
C	SER146
C	TRP147
C	VAL148
C	TYR188
C	TYR195
C	HOH425
C	HOH465
C	HOH466
C	HOH487
C	HOH494
C	HOH533
C	HOH537
C	HOH540
C	HOH566

site_id	AC5
Number of Residues	18
Details	binding site for residue 40P D 301

Chain	Residue
C	THR36
C	TYR55
C	ILE118
C	ASP164
C	SER167
C	HOH483
D	TYR93
D	SER146
D	TRP147
D	VAL148
D	TYR188
D	TYR195
D	HOH485
D	HOH500
D	HOH518
D	HOH529
D	HOH540
D	HOH575

site_id	AC6
Number of Residues	7
Details	binding site for residue CA D 302

Chain	Residue
D	SER166
D	HOH552
D	HOH553
D	HOH554
E	CL302
E	HOH448
E	HOH555

site_id	AC7
Number of Residues	17
Details	binding site for residue 40P E 301

Chain	Residue
E	HOH514
E	HOH517
E	HOH555
D	THR36
D	TYR55
D	ARG79
D	ILE118
D	ASP164
D	SER167
E	TYR93
E	SER146
E	TRP147
E	VAL148
E	CYS191
E	TYR195
E	HOH448
E	HOH479

site_id	AC8
Number of Residues	2
Details	binding site for residue CL E 302

Chain	Residue
D	CA302
E	HOH555

site_id	AC9
Number of Residues	15
Details	binding site for residue 40P F 301

Chain	Residue
F	TYR93
F	SER146
F	TRP147
F	VAL148
F	TYR188
F	TYR195
F	HOH446
F	HOH459
F	HOH465
F	HOH475
F	HOH540
F	HOH561
J	THR36
J	TYR55
J	SER167

site_id	AD1
Number of Residues	16
Details	binding site for residue 40P G 301

Chain	Residue
F	THR36
F	TYR55
F	SER167
G	TYR93
G	SER146
G	TRP147
G	VAL148
G	TYR188
G	TYR195
G	HOH433
G	HOH457
G	HOH461
G	HOH467
G	HOH487
G	HOH493
G	HOH526

site_id	AD2
Number of Residues	15
Details	binding site for residue 40P H 301

Chain	Residue
G	THR36
G	TYR55
G	ILE118
G	SER167
G	HOH449
H	TYR93
H	SER146
H	TRP147
H	VAL148
H	TYR188
H	TYR195
H	HOH485
H	HOH499
H	HOH533
H	HOH555

site_id	AD3
Number of Residues	17
Details	binding site for residue 40P I 301

Chain	Residue
H	THR36
H	TYR55
H	ILE118
H	ASP164
H	SER167
I	TYR93
I	SER146
I	TRP147
I	VAL148
I	TYR188
I	TYR195
I	HOH406
I	HOH463
I	HOH475
I	HOH492
I	HOH529
I	HOH561

site_id	AD4
Number of Residues	6
Details	binding site for residue CA I 302

Chain	Residue
I	SER166
I	HOH533
I	HOH543
J	CL302
J	HOH506
J	HOH514

site_id	AD5
Number of Residues	18
Details	binding site for residue 40P J 301

Chain	Residue
I	THR36
I	TYR55
I	ILE118
I	ASP164
I	SER167
J	TYR93
J	SER146
J	TRP147
J	VAL148
J	TYR188
J	GLU193
J	TYR195
J	HOH453
J	HOH471
J	HOH506
J	HOH539
J	HOH562
J	HOH570

site_id	AD6
Number of Residues	2
Details	binding site for residue CL J 302

Chain	Residue
I	CA302
J	HOH514

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)