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4XHD

STRUCTURE OF HUMAN PREGNANE X RECEPTOR LIGAND BINDING DOMAIN WITH COMPOUND-1

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues8
Detailsbinding site for residue GOL A 501
ChainResidue
ATHR161
AASP163
APHE166
ATYR249
AMET250
AGLY253
AARG287
AHOH664

site_idAC2
Number of Residues11
Detailsbinding site for residue 40U A 502
ChainResidue
AMET243
AGLN285
APHE288
ATRP299
ATYR306
AMET323
AHIS407
APHE420
AHOH624
AHOH656
AVAL211

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000269|PubMed:12578355, ECO:0007744|PDB:1M13
ChainResidueDetails
AASN224
ASER262
APRO384

227111

PDB entries from 2024-11-06

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